Literature DB >> 33714655

Adverse events following immunization: Findings from 2017/2018 measles vaccination campaign, Nigeria AEFI reporting in 2017/2018 measles vaccination campaign.

Ene Gbenewei1, Terna Nomhwange2, Lydia Taiwo3, Isiaka Ayodeji4, Kabir Yusuf1, Anne E Jean Baptiste4, Peter Nsubuga5, Fiona Braka4, Joseph Oteri1, Faisal Shuaib1.   

Abstract

INTRODUCTION: An Adverse event following immunization (AEFI) is an untoward medical occurrence following immunization and which may not have a necessary causal relationship with the usage of a vaccine. The World Health Organization categories AEFI into two; serious and non-serious. An AEFI is considered serious if it is life-threatening, requires inpatient hospitalization or results in death. The measles vaccine is safe and effective however because it is a live-attenuated injectable vaccine it is more prone to AEFI as compared to non-injectable vaccines when given in large numbers over a short period as is the nature of measles mass vaccination campaigns (MVC). This article describes Nigeria's experience on AEFI reporting during the 2017/2018 Measles vaccination campaign (MVC).
METHODS: We reviewed various materials which included the Open Data Kit (ODK) which is an open source smartphone-based data collecting tool, operations room reports, measles campaign tally sheets, AEFI line listing forms, the post measles campaign coverage survey report and the report of the AEFI national expert committee review of the 2017/2018 Nigeria measles MVC.
RESULTS: A total of 6,214 suspected cases of AEFI were line listed from all 36 states and the Federal Capital Territory(FCT) during the 2017/2018 MVC with Fever(38%) and pain at injection site the (30%)most common reports. Overall, 99.7% AEFIs were reported to be non-serious AEFIs, with almost all cases resolved fully with no long-term sequalae.. The national incidence of suspected AEFI per 100,000 population was 16.3 with subnational incidence highest in Kebbi state (101.3/100,000) and lowest in Bayelsa state (0.8/100,000).
CONCLUSION: Adequate AEFI reporting, Investigation and management remains important in managing the risk of a disruption of mass campaigns. The deployment of supervisors during campaign may play an important role in improving the identification and reporting of suspected AEFI. Further inquiries about AEFIs during the post campaign coverage evaluation also played a role in improving AEFI reporting and documentation. The real-time, on the spot, follow up by the national operations team helped with decision making and intervention including AEFI investigations and assessments.
Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  AEFI (Adverse Event following Immunization); Measles; Nigeria; Supplemental immunization activities

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Year:  2021        PMID: 33714655     DOI: 10.1016/j.vaccine.2021.02.067

Source DB:  PubMed          Journal:  Vaccine        ISSN: 0264-410X            Impact factor:   3.641


  1 in total

1.  Understanding and experience of adverse event following immunization (AEFI) and its consequences among healthcare providers in Kebbi State, Nigeria: a qualitative study.

Authors:  Ashiru Mohammed Mustapha; Shafiu Muhammad Dansanda; Kehinde Kazeem Kanmodi; Hafsat Abubakar; Semeeh Akinwale Omoleke; Biniam Getachew; Abubakar Isyaku; Abdulrasheed Bello Aliyu; Zahraddeen Ibrahim Lawal; Haruna Abdullahi Kangiwa
Journal:  BMC Health Serv Res       Date:  2022-06-03       Impact factor: 2.908

  1 in total

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