Literature DB >> 33711361

Mesenchymal stem cells: Biological characteristics and application in disease therapy.

Songyue Lou1, Yongtao Duan2, Huizong Nie3, Xujie Cui4, Jialing Du5, Yongfang Yao6.   

Abstract

Mesenchymal stem cells (MSCs) are multipotent stem cells. In addition to the capacity for self-renewal and multipotential differentiation, MSCs also have the following characteristics. MSCs can exert immunomodulatory functions through interaction with innate or adaptive immune cells, MSCs with poor immunogenicity can be used for allogeneic transplantation, and MSCs can "home" to inflammation and tumour sites. Based on these biological properties, MSCs demonstrate broad clinical application prospects in the treatment of tissue injury, autoimmune diseases, transplantation, cancer and other inflammation-related diseases. In this review we describe the biological characteristics of MSCs and discuss the research advances of MSCs in regenerative medicine, immunomodulation, oncology, and COVID-19, to fully understand the range of diseases in which MSC therapy may be beneficial.
Copyright © 2021 Elsevier B.V. and Société Française de Biochimie et Biologie Moléculaire (SFBBM). All rights reserved.

Entities:  

Keywords:  Homing; Immunomodulation; Mesenchymal stem cells; Regenerative medicine; Tumor

Mesh：

Year:  2021        PMID： 33711361     DOI： 10.1016/j.biochi.2021.03.003

Source DB:  PubMed          Journal:  Biochimie        ISSN： 0300-9084            Impact factor:   4.079


  10 in total

Review 1.  Administration of mesenchymal stem cells in diabetic kidney disease: mechanisms, signaling pathways, and preclinical evidence.

Authors:  Yuexin Zhu; Manyu Luo; Xue Bai; Yan Lou; Ping Nie; Shan Jiang; Jicui Li; Bing Li; Ping Luo
Journal:  Mol Cell Biochem       Date:  2022-04-25       Impact factor: 3.396

2.  Dyslipidemia induced by lipid diet in late gestation donor impact on growth kinetics and in vitro potential differentiation of umbilical cord Wharton's Jelly mesenchymal stem cells in goats.

Authors:  Alessandra Façanha Bezerra; Juliana Paula Martins Alves; César Carneiro Linhares Fernandes; Camila Muniz Cavalcanti; Maria Raquel Lopes Silva; Alfredo José Herrera Conde; Gildas Mbemya Tetaping; Anna Clara Accioly Ferreira; Luciana Magalhães Melo; Ana Paula Ribeiro Rodrigues; Davide Rondina
Journal:  Vet Res Commun       Date:  2022-09-20       Impact factor: 2.816

3.  The Role of Hypoxia in Improving the Therapeutic Potential of Mesenchymal Stromal Cells. A Comparative Study From Healthy Lung and Congenital Pulmonary Airway Malformations in Infants.

Authors:  Serena Silvestro; Francesca Diomede; Luigi Chiricosta; Valeria Domenica Zingale; Guya Diletta Marconi; Jacopo Pizzicannella; Andrea Valeri; Maria Antonietta Avanzini; Valeria Calcaterra; Gloria Pelizzo; Emanuela Mazzon
Journal:  Front Bioeng Biotechnol       Date:  2022-06-14

Review 4.  The Dual Role of Mesenchymal Stromal Cells and Their Extracellular Vesicles in Carcinogenesis.

Authors:  Zarema Gilazieva; Aleksei Ponomarev; Albert Rizvanov; Valeriya Solovyeva
Journal:  Biology (Basel)       Date:  2022-05-25

5.  The influence of association between aging and reduced protein intake on some immunomodulatory aspects of bone marrow mesenchymal stem cells: an experimental study.

Authors:  Renaira Oliveira da Silva; Araceli Aparecida Hastreiter; Gabriela Kodja Vivian; Carolina Carvalho Dias; Andressa Cristina Antunes Santos; Edson Naoto Makiyama; Primavera Borelli; Ricardo Ambrósio Fock
Journal:  Eur J Nutr       Date:  2022-05-05       Impact factor: 4.865

Review 6.  Advances in the application of low-intensity pulsed ultrasound to mesenchymal stem cells.

Authors:  Peng Xia; Yi Shi; Xiaoju Wang; Xueping Li
Journal:  Stem Cell Res Ther       Date:  2022-05-26       Impact factor: 8.079

7.  Competitive Hybridization of a Microarray Identifies CMKLR1 as an Up-Regulated Gene in Human Bone Marrow-Derived Mesenchymal Stem Cells Compared to Human Embryonic Fibroblasts.

Authors:  Hee-Yeon Cho; Sooho Lee; Ji-Hong Park; Yoon Hae Kwak; HaeYong Kweon; Dongchul Kang
Journal:  Curr Issues Mol Biol       Date:  2022-03-28       Impact factor: 2.976

Review 8.  Regulation of the mesenchymal stem cell fate by interleukin-17: Implications in osteogenic differentiation.

Authors:  Jelena Krstić; Slavko Mojsilović; Sonja S Mojsilović; Juan F Santibanez
Journal:  World J Stem Cells       Date:  2021-11-26       Impact factor: 5.326

9.  Stem Cells from Human Exfoliated Deciduous Teeth Attenuate Atopic Dermatitis Symptoms in Mice through Modulating Immune Balance and Skin Barrier Function.

Authors:  Hao Xiong; Jin Yang; Tao Liu; Guangren Liu; Yongzhi Han; Xiuqin Dong
Journal:  Mediators Inflamm       Date:  2022-07-21       Impact factor: 4.529

10.  Clinical applications of mesenchymal stromal cell-based therapies for pulmonary diseases: An Update and Concise Review.

Authors:  Xiaobo Chen; Feng Wang; Zhiwei Huang; Yan Wu; Jie Geng; Yuliang Wang
Journal:  Int J Med Sci       Date:  2021-06-01       Impact factor: 3.738
  10 in total

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