| Literature DB >> 33709346 |
Saif Ali1, Sharon Jung1, Shuktika Nandkeolyar1, Liset Stoletniy1, Antoine Sakr1, Frederik H Verbrugge2,3, Anthony Hilliard1, Dmitry Abramov4.
Abstract
The inpatient treatment of acute heart failure (AHF) is aimed at achieving euvolemia, relieving symptoms, and reducing rehospitalization. Adequate treatment of AHF is rooted in understanding the pharmacokinetics and pharmacodynamics of select diuretic agents used to achieve decongestion. While loop diuretics remain the primary treatment of AHF, the dosing strategies of loop diuretics and the use of adjunct diuretic classes to augment clinical response can be complex. This review examines the latest strategies for diuretic management in patients with AHF, including dosing and monitoring strategies, interaction of diuretics with other medication classes, use adjunctive therapies, and assessing endpoints for diuretic. The goal of the review is to guide the reader through commonly encountered clinical scenarios and pitfalls in the diuretic management of patients with AHF.Entities:
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Year: 2021 PMID： 33709346 DOI： 10.1007/s40256-020-00463-5
Source DB: PubMed Journal: Am J Cardiovasc Drugs ISSN： 1175-3277 Impact factor: 3.571