Economic impact of orthopaedic care for non-fatal gunshot wounds: analysis of a public health crisis.

BACKGROUND: The purpose of this study was to perform an epidemiological evaluation and an economic analysis of 90-day costs associated with non-fatal gunshot wounds (GSWs) to the extremities, spine and pelvis requiring orthopaedic care in the United States.
METHODS: A retrospective epidemiological review of the Medicare national patient record database was conducted from 2005 to 2014. Incidence, fracture location and costs associated where evaluated. Those patients identified through International Classification of Disease (ICD)-9 revision codes and Current Procedural Terminology (CPT) Codes who sustained a fracture secondary to a GSW. Any type of surgical intervention including incision and drainage, open reduction with internal fixation, closed reduction and percutaneous fixation, etc. were identified to analyze, and evaluate costs of care as seen by charges and reimbursements to the payer. The 90-day period after initial fracture care was queried.
RESULTS: A total of 9,765 patients required surgical orthopaedic care for GSWs. There was a total of 2,183 fractures due to GSW treated operatively in 2,201 patients. Of these, 22% were femur fractures, 18.3% were hand/wrist fractures and 16.7% were ankle/foot fractures. A majority of patients were male (83.3%) and under 65 years of age (56.3%). Total charges for GSW requiring orthopedic care were $513,334,743 during the 10-year study period. Total reimbursement for these patients were $124,723,068. Average charges per patient were highest for fracture management of the spine $431,021.33, followed by the pelvis $392,658.45 and later by tibia/fibula fractures $342,316.92.
CONCLUSIONS: The 90-day direct charges and reimbursements of orthopedic care for non-fatal GSWs are of significant amounts per patient. While the number of fatal GSWs has received much attention, non-fatal GSWs have a large economic and societal impact that warrants further research and consideration by the public and policy makers. 2021 Annals of Translational Medicine. All rights reserved.

Introduction

The United States (U.S.) has the highest number of firearm-related deaths among developed countries which has been deemed a public health crisis (1-4). In 2015, the number of firearm-related deaths including suicides (36,252) was similar to number of deaths from traffic accidents (36,161) (1). Based on data from a publicly accessible online resource that independently tracks gun violence related events in the US (3), the incidence of gun violence increased by 15% from 51,858 incidents in 2014 to 61,552 incidents in 2017 (3). Gun violence related deaths increased by 19% between 2014 and 2017 to a total of 15,586 deaths (3). The lifetime medical and work-loss costs of all homicides in the year 2013 were estimated by the Centers for Disease Control (CDC) at approximately 26 billion dollars (5). However, the number non-fatal gunshot wounds (GSW) increased by 26% to 31,181 injuries from 2014 to 2017 to approximately twice the number of gun violence deaths (3). While attention in the media is mostly paid to gun violence deaths, the high and increasing number of injuries from non-fatal GSWs and their societal and economic impact appear to be overlooked as a point of contention.

The treatment of GSWs is complex and often requires the inclusion of multiple medical and surgical subspecialties and major allocation of hospital resources. Specifically in orthopaedic surgery, non-fatal GSWs may require multiple procedures ranging from irrigation and debridement to operative fracture fixation or amputation due to associated major soft tissue injuries (6-8). Management for orthopedic related injuries secondary to gunshot wounds are dependent on the kinetic energy of penetrating bullet. Low velocity bullets (muzzle velocity <350 meters per second; i.e., most handguns) are usually treated with fracture/soft tissue stabilization and local wound care. Alternatively, high velocity bullets (muzzle velocity >600 meters per second; assault rifles) are treated with fracture/soft tissue stabilization and irrigation with debridement. Nonetheless, GSW confers complex cases that not only lead to greater healthcare resource utilization, but also to loss of work productivity, decline in quality of life and long-term disability (4,9-12). Despite the aforementioned, the economic impact of non-fatal GSWs has not been previously described. This is important as healthcare related costs have continued to increase despite active measures taken by legislators and policy makers.

The purpose of this study was to perform a descriptive epidemiological study of the direct economic burden of GSWs requiring orthopaedic care in the United States using the Medicare national database. National healthcare databases provide a unique platform and opportunity to further study and understand gun violence related events (13-15). In the era of decreased funding for gun violence research from the National Institutes of Health and limited resource allocation towards gun violence by the CDC (16), it is imperative that independent groups pursue research on this topic. While the emotional and societal impact of gun violence is undisputed, the economic costs of non-fatal GSWs remains underreported, but may have a significant influence on the current debate regarding gun violence and gun control. We present the following article in accordance with the MDAR reporting checklist (available at http://dx.doi.org/10.21037/atm-20-1064).

Methods

This study utilized a publically available database and as such did not require approval from IRB. The current study was conducted in accordance with the Declaration of Helsinki (as revised in 2013).

A retrospective epidemiological analysis of the Medicare national database was performed. The primary research question in place was: what are the recent trends in GSW related fractures to the extremities, pelvis and spine and what is their cost. The PearlDiver Server (Colorado Springs, CO) was used as a platform to access and analyze these patients. The dataset was comprised of the Medicare Standard Analytical Files (SAF) which allows for a comprehensive analysis of over 50 million lives based on records captured from January 2005 to December 2014. Patients can be tracked longitudinally and are identified through International Classification of Disease 9th revision codes (ICD) and Current Procedural Terminology (CPT) codes. Patients with an ICD-9 code of an injury related to a GSW resulting in surgical treatment were included in the study. Patients were stratified based on any orthopaedic procedures performed as described previously (17).

Anatomical regions of interest were separated into: humerus, radius/ulna, wrist/hand, femur, tibia/fibula, foot and ankle, spine and pelvis (17).

Statistical analysis

Demographic data was captured and analyzed based on annual incidences per 100,000 people, trends over time, length of stay and costs. Costs were depicted by charges and reimbursements related to the procedures performed on GSW patients. Both charges and reimbursements are included.

Descriptive statistics were reported as means and standard deviations (SD). Linear regressions were used to analyze trends over time (SPSS 20, IBM Corporation, Armonk, NY). A P value of 0.05 was set as the threshold for statistical significance.

Results

GSW-related fractures: incidence and demographics

This study identified 9,765 patients treated for GSWs in the Medicare database for a mean annual incidence of 3.88 (SD 3.2) per 100,000 patients without significant annual variation (P=0.923). There were a total of 2,183 fractures due to GSW treated operatively with an annual incidence of 1.825 per 100,000 patients (SD 0.779), without a significant annual variation (P=0.948).

The majority of patients sustaining GSWs were aged 64 and under (55.3%), and men overwhelmingly suffered from these injuries relative to their female counterparts (82.3 vs. 16.5%) ().

Table 1

Demographic information for patients who sustained GSW between 2005 and 2014

	Data (%)
Age distribution
Unknown	1.0
64 and under	55.3
65–69	15.4
70–74	11.7
75–79	8.0
80–84	5.3
85 and over	3.2
Gender distribution
Female	16.5
Male	82.3
Unknown	1.2

The annual incidence of GSW-related humerus, radius/ulna, wrist/hand, femur, tibia/fibula, ankle/foot, pelvis, and spine fractures saw a steady increase from 2005 to 2008 (). From 2008 to 2010, there was a considerable rise in the incidence of all fractures secondary to GSWs, which steadily decreased in all fracture types from 2011 through 2014. Throughout the study period, wrist and/or hand and ankle and/or foot fractures remained the predominant fracture types.

Table 2

Annual incidence of fractures due to GSW (incidence per 100,000)

Year	Humerus	Radius and/or Ulna	Wrist and/or Hand	Femur	Tibia and/or Fibula	Ankle and/or Foot	Pelvis	Spine
2005	0.153	0.173	0.382	0.276	0.228	0.536	0.086	0.295
2006	0.145	0.195	0.357	0.245	0.218	0.449	0.076	0.330
2007	0.195	0.210	0.512	0.283	0.214	0.459	0.065	0.401
2008	0.207	0.249	0.599	0.319	0.219	0.542	0.080	0.353
2009	0.322	0.515	1.140	0.674	0.531	1.074	0.267	0.737
2010	0.426	0.560	1.509	0.848	0.606	1.175	0.288	0.917
2011	0.196	0.260	0.561	0.358	0.297	0.561	0.109	0.444
2012	0.148	0.181	0.411	0.348	0.248	0.526	0.092	0.293
2013	0.150	0.157	0.378	0.308	0.201	0.473	0.088	0.315
2014	0.139	0.139	0.354	0.307	0.204	0.416	0.080	0.307

The tendency for surgical treatment of fractures sustained secondary to GSW demonstrated a similar trend (). From 2005 to 2008, all fracture types had an increasingly greater likelihood of being treated surgically, with a peak in 2009 and 2010, and a steady decline through 2014. Throughout this period, GSW-related wrist and/or hand, femur, and ankle and/or foot fractures were operated on in the highest rates.

Figure 1

Incidence of GSW fractures treated surgically, stratified by anatomical location (incidence per 100,000).

When the total number of GSW-related fractures were reported relative to the number of fractures treated surgically, femur fractures demonstrated the highest incidence of operative treatment (79.77%), followed by tibia and/or fibula fractures (60.99%) and humerus fractures (52.77%) (). Spine fractures secondary to GSWs were the least likely (34.81%) to be treated surgically.

Table 3

Incidence of fractures secondary to GSW, and the proportion of fractures treated surgically

Anatomical site	Number of GSW causing fractures	Number of fractures treated surgically	Proportion of fractures treated surgically
Humerus	322	168	52.17%
Radius and/or Ulna	401	198	49.38%
Wrist and/or Hand	1,099	399	36.31%
Femur	603	481	79.77%
Tibia and/or Fibula	464	283	60.99%
Ankle and/or Foot	922	364	39.48%
Pelvis	201	78	38.81%
Spine	609	212	34.81%

Economic burden of GSW-related fractures

Total charges for GSW requiring orthopedic care were $513,334,743 during the 10-year study period (). Total reimbursement for these patients was $124,723,068. Average charges per patient were highest for fracture management of the spine ($431,021.33), followed by the pelvis ($392,658.45) and later by tibia/fibula fractures ($342,316.92). Patients sustaining GSW-related pelvis fractures had the greatest average length of stay (6.3 days), while those recovering from wrist and/or hand (2.6 days) and radius and/or ulna fractures (3.2 days) required the shortest hospital stay.

Table 4

Average charges and reimbursements per patient, stratified per anatomic location

Anatomic Location	Number of fractures operated on	Average charge/patient	Average amount paid/patient	Average length of stay (days)
Humerus	168	$329,219.93	$71,214.98	3.691
Radius and/or Ulna	198	$288,831.14	$72,995.71	3.206
Wrist and/or Hand	399	$211,168.83	$54,256.97	2.558
Femur	481	$319,188.44	$73,031.06	4.219
Tibia and/or Fibula	283	$342,316.92	$78,972.17	4.354
Ankle and/or Foot	364	$277,332.56	$66,167.75	3.434
Pelvis	78	$392,658.45	$87,699.74	6.304
Spine	212	$431,021.33	$107,098.92	4.147

Discussion

The purpose of this study was to examine a national representative sample of patients undergoing orthopedic care for GSWs to illustrate the economic effects of these injuries in the US. The approximate healthcare cost for GSW fractures related injuries over the 10-year study period was approximately 0.5 billion dollars based on charges from direct care alone. Early research on gun violence in the 1980’s analyzed national trends in GSWs and the costs of daily hospitalization and emotional costs (18). The study concluded at the time that the economic loss of premature death due to firearms occurred at $4 billion dollars annually (18). A recent study from the CDC estimated the medical and work-loss costs of all homicides in the year 2013 at approximately 26 billion dollars (5) which is similar to the gross domestic product of El Salvador in 2017 (19). For comparison, a study evaluating surgical fixation of hip fracture with a Medicare database found that hemiarthroplasty 90-day claims payments occurred at a mean of $28,952 2014-adjusted dollars (20).

The incidence of GSW events to the extremities, pelvis and spine in this study (3.88 per 100,000 people) is slightly higher than the rate of deaths from drunk driving (3.77 per 100,000 people) based on available and representative data from the CDC (21). Furthermore, the number of gun violence related deaths reported in 2017 (15,586) (3) is similar to number of deaths attributed to esophageal cancer (15,690) (22) and the number of prescription opioid pain reliever associated deaths [excluding non-methadone synthetics (fentanyl)] in 2015 (approximately 17,000) (23). With the rising number of opioid pain medication related death in the US, an emergency declaration was issued by the President of the United States of America to delegate funding towards prevention, treatment and of opioid addiction and overdose as a public health emergency. Epidemiological studies have demonstrated that primary prevention is cost-effective and efficient for overall cost-savings, thus emphasizing the likely value that new strategies with greater preventive methods may provide (24,25). While the increase in gun violence related death has not increased as dramatically in recent years as opioid addiction and deaths from overdose, further funding and research into causes of gun related violence and possible preventive measures to decrease the incidence of GSW related injuries could have a similar impact as mandated seat belt use (26).

Orthopedic procedures most commonly included I&D, ORIF and closed reduction internal fixation (intramedullary nailing) of long bones and hand fractures. This is in-line with trauma guidelines and other articles, that favor initial I&D of fractures due to GSWs (16,27-29). Nwachukwu et al. evaluated the quality of cost utility analyses in orthopedic trauma and concluded that certain treatments such as total hip arthroplasty for femoral neck fractures, ORIF for distal radius fractures and scaphoid fractures and limb salvage for complex tibial fractures were cost-effective at delivering care (30). These findings highlight the value produced by prompt high-level care provided for these complex fractures, but also allows to depict why such high expenditure takes place that may be a contributing factor to the high percentage of Gross Domestic Product (GDP) spent on healthcare in the U.S. Of note, spine fractures were the ones found to have higher costs in this cohort, even with non-operative management. This is not surprising as these patients usually require intensive care unit monitoring, multiple imaging modalities, a great deal of acute rehabilitation and multispecialty consultation (31,32). Our results reveal a significant economic impact of non-fatal GSW for on orthopedic care providers. As such we suggest physician led efforts aimed at legislative policy change to minimize the incidence of non-fatal GSW. Guns shot wounds from high velocity firearms (>600 meters second) confer higher morbidity and mortality rates. Accordingly, physician led policy should maybe be directed to limiting access to military grade weapons and assault rifles. Furthermore, orthopedists and hospital institutions should invest time and effort in educating their care region on the importance of gun safety. Finally, more efforts are necessary to establish physician-legislature coalitions in order to provide legislation with the most up-to-date information.

The findings of this study need to be interpreted in light several limitations. This was a retrospective analysis of a national database that required accurate coding by the health providers to decrease selection bias. Therefore, the findings of this study may underestimate the true incidence and true costs of non-fatal GSW treatment including orthopaedic surgical care. Patients were only included in this study if they had a 90-day follow-up in the national database, which were then labeled as non-fatal GSWs. This may have led to the inclusion of patients that succumbed to their injuries after the 90-day follow-up period. Based on the methodology of the study, fracture type, comminution, neurovascular involvement and/or other concomitant injuries were unable to be assessed in detail. Nonetheless, the usefulness of this methodology allows for estimation of costs with validates measurements. Charges and reimbursements associated with GSW care in the U.S where found to correlate with the 3:1 ratio of charges to reimbursements as has been done in the past (17). This demonstrates the predictability of these costs and how future projections may allow for proper budget estimation and resource allocation, if no policy changes take place that could transcend on the incidence of GSW events. No adjustments were made for inflation or regional differences as all these factors would affect equally patients nationally. Costs of lost productive time, rehabilitation and follow-up care were not included due to the study design, likely leading to a gross underestimation of the true costs of non-fatal GSWs. Quality of life adjusted years and/or cost-effectiveness evaluations were not performed.

Conclusions

Despite the limitations of this national healthcare database driven study, there appears to be a significant economic burden of non-fatal GSW to the healthcare system that may have been underestimated and underreported.

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