Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Gut microbiota-derived metabolites in the regulation of host immune responses and immune-related inflammatory diseases.

Literature DB >> 33707689

Gut microbiota-derived metabolites in the regulation of host immune responses and immune-related inflammatory diseases.

Abstract

The gut microbiota has a critical role in the maintenance of immune homeostasis. Alterations in the intestinal microbiota and gut microbiota-derived metabolites have been recognized in many immune-related inflammatory disorders. These metabolites can be produced by gut microbiota from dietary components or by the host and can be modified by gut bacteria or synthesized de novo by gut bacteria. Gut microbiota-derived metabolites influence a plethora of immune cell responses, including T cells, B cells, dendritic cells, and macrophages. Some of these metabolites are involved in the pathogenesis of immune-related inflammatory diseases, such as inflammatory bowel diseases, diabetes, rheumatoid arthritis, and systemic lupus erythematosus. Here, we review the role of microbiota-derived metabolites in regulating the functions of different immune cells and the pathogenesis of chronic immune-related inflammatory diseases.

Entities: Chemical

Keywords: B cells; T cells; autoimmune diseases; gut microbiota; metabolites

Mesh：

Year: 2021 PMID： 33707689 PMCID： PMC8115644 DOI： 10.1038/s41423-021-00661-4

Source DB: PubMed Journal: Cell Mol Immunol ISSN： 1672-7681 Impact factor: 11.530

197 in total

Review 1. The cross talk between microbiota and the immune system: metabolites take center stage.

Authors: Hagit Shapiro; Christoph A Thaiss; Maayan Levy; Eran Elinav
Journal: Curr Opin Immunol Date: 2014-07-26 Impact factor: 7.486

2. A metagenome-wide association study of gut microbiota in type 2 diabetes.

Authors: Junjie Qin; Yingrui Li; Zhiming Cai; Shenghui Li; Jianfeng Zhu; Fan Zhang; Suisha Liang; Wenwei Zhang; Yuanlin Guan; Dongqian Shen; Yangqing Peng; Dongya Zhang; Zhuye Jie; Wenxian Wu; Youwen Qin; Wenbin Xue; Junhua Li; Lingchuan Han; Donghui Lu; Peixian Wu; Yali Dai; Xiaojuan Sun; Zesong Li; Aifa Tang; Shilong Zhong; Xiaoping Li; Weineng Chen; Ran Xu; Mingbang Wang; Qiang Feng; Meihua Gong; Jing Yu; Yanyan Zhang; Ming Zhang; Torben Hansen; Gaston Sanchez; Jeroen Raes; Gwen Falony; Shujiro Okuda; Mathieu Almeida; Emmanuelle LeChatelier; Pierre Renault; Nicolas Pons; Jean-Michel Batto; Zhaoxi Zhang; Hua Chen; Ruifu Yang; Weimou Zheng; Songgang Li; Huanming Yang; Jian Wang; S Dusko Ehrlich; Rasmus Nielsen; Oluf Pedersen; Karsten Kristiansen; Jun Wang
Journal: Nature Date: 2012-09-26 Impact factor: 49.962

3. A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes.

Authors: Ben P Willing; Johan Dicksved; Jonas Halfvarson; Anders F Andersson; Marianna Lucio; Zongli Zheng; Gunnar Järnerot; Curt Tysk; Janet K Jansson; Lars Engstrand
Journal: Gastroenterology Date: 2010-10-08 Impact factor: 22.682

Review 4. Gut microbiota, metabolites and host immunity.

Authors: Michelle G Rooks; Wendy S Garrett
Journal: Nat Rev Immunol Date: 2016-05-27 Impact factor: 53.106

5. The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment.

Authors: Xuan Zhang; Dongya Zhang; Huijue Jia; Qiang Feng; Donghui Wang; Di Liang; Xiangni Wu; Junhua Li; Longqing Tang; Yin Li; Zhou Lan; Bing Chen; Yanli Li; Huanzi Zhong; Hailiang Xie; Zhuye Jie; Weineng Chen; Shanmei Tang; Xiaoqiang Xu; Xiaokai Wang; Xianghang Cai; Sheng Liu; Yan Xia; Jiyang Li; Xingye Qiao; Jumana Yousuf Al-Aama; Hua Chen; Li Wang; Qing-Jun Wu; Fengchun Zhang; Wenjie Zheng; Yongzhe Li; Mingrong Zhang; Guangwen Luo; Wenbin Xue; Liang Xiao; Jun Li; Wanting Chen; Xun Xu; Ye Yin; Huanming Yang; Jian Wang; Karsten Kristiansen; Liang Liu; Ting Li; Qingchun Huang; Yingrui Li; Jun Wang
Journal: Nat Med Date: 2015-07-27 Impact factor: 53.440

6. Fecal microbiota in early rheumatoid arthritis.

Authors: Jussi Vaahtovuo; Eveliina Munukka; Mika Korkeamäki; Reijo Luukkainen; Paavo Toivanen
Journal: J Rheumatol Date: 2008-06-01 Impact factor: 4.666

7. Gut Microbiota in Human Systemic Lupus Erythematosus and a Mouse Model of Lupus.

Authors: Xin M Luo; Michael R Edwards; Qinghui Mu; Yang Yu; Miranda D Vieson; Christopher M Reilly; S Ansar Ahmed; Adegbenga A Bankole
Journal: Appl Environ Microbiol Date: 2018-01-31 Impact factor: 4.792

8. Intestinal dysbiosis associated with systemic lupus erythematosus.

Authors: Arancha Hevia; Christian Milani; Patricia López; Adriana Cuervo; Silvia Arboleya; Sabrina Duranti; Francesca Turroni; Sonia González; Ana Suárez; Miguel Gueimonde; Marco Ventura; Borja Sánchez; Abelardo Margolles
Journal: MBio Date: 2014-09-30 Impact factor: 7.867

9. Dynamics of the human gut microbiome in inflammatory bowel disease.

Authors: Jonas Halfvarson; Colin J Brislawn; Regina Lamendella; Yoshiki Vázquez-Baeza; William A Walters; Lisa M Bramer; Mauro D'Amato; Ferdinando Bonfiglio; Daniel McDonald; Antonio Gonzalez; Erin E McClure; Mitchell F Dunklebarger; Rob Knight; Janet K Jansson
Journal: Nat Microbiol Date: 2017-02-13 Impact factor: 17.745

10. Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis.

Authors: Jose U Scher; Andrew Sczesnak; Randy S Longman; Nicola Segata; Carles Ubeda; Craig Bielski; Tim Rostron; Vincenzo Cerundolo; Eric G Pamer; Steven B Abramson; Curtis Huttenhower; Dan R Littman
Journal: Elife Date: 2013-11-05 Impact factor: 8.140

25 in total

1. Integrin αEβ7⁺ T cells direct intestinal stem cell fate decisions via adhesion signaling.

Authors: Shiyang Chen; Yajuan Zheng; Xiaojuan Ran; Hui Du; Hua Feng; Lei Yang; Yating Wen; Changdong Lin; Shihui Wang; Mengwen Huang; Zhanjun Yan; Dianqing Wu; Hongyan Wang; Gaoxiang Ge; An Zeng; Yi Arial Zeng; Jianfeng Chen
Journal: Cell Res Date: 2021-09-13 Impact factor: 25.617

Review 10. Bacillus subtilis-Based Probiotic Improves Skeletal Health and Immunity in Broiler Chickens Exposed to Heat Stress.

Authors: Sha Jiang; Fei-Fei Yan; Jia-Ying Hu; Ahmed Mohammed; Heng-Wei Cheng
Journal: Animals (Basel) Date: 2021-05-21 Impact factor: 2.752

Gut microbiota-derived metabolites in the regulation of host immune responses and immune-related inflammatory diseases.

Review 1. The cross talk between microbiota and the immune system: metabolites take center stage.

2. A metagenome-wide association study of gut microbiota in type 2 diabetes.

3. A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes.

Review 4. Gut microbiota, metabolites and host immunity.

5. The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment.

6. Fecal microbiota in early rheumatoid arthritis.

7. Gut Microbiota in Human Systemic Lupus Erythematosus and a Mouse Model of Lupus.

8. Intestinal dysbiosis associated with systemic lupus erythematosus.

9. Dynamics of the human gut microbiome in inflammatory bowel disease.

10. Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis.

1. Integrin αEβ7⁺ T cells direct intestinal stem cell fate decisions via adhesion signaling.

Review 2. Long-distance relationships - regulation of systemic host defense against infections by the gut microbiota.

3. A balanced gut microbiota is essential to maintain health in captive sika deer.

Review 4. Food for thought - ILC metabolism in the context of helminth infections.

5. Comparison of Intestinal Microbes in Noninfectious Anterior Scleritis Patients With and Without Rheumatoid Arthritis.

6. Indole-3-Propionic Acid as a Potential Therapeutic Agent for Sepsis-Induced Gut Microbiota Disturbance.

Review 7. Metabolomics: The Key to Unraveling the Role of the Microbiome in Visceral Pain Neurotransmission.

Review 8. Microbial Metabolites in Multiple Sclerosis: Implications for Pathogenesis and Treatment.

Review 9. The influence of microbiota-derived metabolites on viral infections.

Review 10. Bacillus subtilis-Based Probiotic Improves Skeletal Health and Immunity in Broiler Chickens Exposed to Heat Stress.