Literature DB >> 33706758

Guided growth in the correction of knee deformity in patients with congenital insensitivity to pain.

Soroush Baghdadi1, Sadegh Saberi1, Taghi Baghdadi2.   

Abstract

BACKGROUND: Orthopedic manifestations of congenital insensitivity to pain (CIP) can be devastating if left untreated. Knee deformities are common in patients with CIP and might lead to joint destruction and loss of walking ability. The purpose of the present study was to report the results and complications of guided growth procedures around the knee in patients with CIP.
METHODS: In a retrospective review, all patients with CIP who underwent guided growth procedures around the knee from 2009 to 2017 at a tertiary referral hospital were evaluated. Patients with secondary insensitivity to pain (e.g., syringomyelia), as well as patients with incomplete records, were excluded. Demographic data, clinical findings, correction rate, and complications were recorded.
RESULTS: Ten knees in six patients fulfilled the inclusion criteria. The median age was 10 (range, 5-12), with a mean follow-up of 31 months (range, 16-56). Distal femoral tension-band hemiepiphysiodesis was the most common procedure, followed by proximal tibial hemiepiphysiodesis. The mean correction rate was 0.28°/month for femoral deformity. Staples were removed prematurely in one patient due to extrusion. No cases of infection or skin dehiscence were observed. None of the patients needed a reconstructive knee procedure during the study period.
CONCLUSIONS: The findings of this study suggest that guided growth procedures might have a role in the correction of knee deformities in patients with CIP. However, the correction rate is lower than that of typically developing children, patients should be closely followed to prevent complications, and stringent patient selection criteria should be followed to ensure success.

Entities:  

Keywords:  Congenital insensitivity to pain; Genu valgum; Guided growth; Hemiepiphysiodesis; Hereditary sensory and motor neuropathy; Knee deformity

Year:  2021        PMID: 33706758      PMCID: PMC7948364          DOI: 10.1186/s13018-021-02304-w

Source DB:  PubMed          Journal:  J Orthop Surg Res        ISSN: 1749-799X            Impact factor:   2.359


  26 in total

Review 1.  Congenital insensitivity to pain: an update.

Authors:  Elna M Nagasako; Anne Louise Oaklander; Robert H Dworkin
Journal:  Pain       Date:  2003-02       Impact factor: 6.961

Review 2.  Mechanisms of disease in hereditary sensory and autonomic neuropathies.

Authors:  Annelies Rotthier; Jonathan Baets; Vincent Timmerman; Katrien Janssens
Journal:  Nat Rev Neurol       Date:  2012-01-24       Impact factor: 42.937

3.  The Ever-elusive Concept of Clinical Judgment.

Authors:  Soroush Baghdadi; Seyyed Mohammad Javad Mortazavi; Taghi Baghdadi
Journal:  J Pediatr Orthop       Date:  2021-01       Impact factor: 2.324

4.  Twenty-one Years with Congenital Insensitivity to Pain: A Case Report.

Authors:  Dnyanesh G Lad; V M Khaleel
Journal:  JBJS Case Connect       Date:  2012 Oct-Dec

5.  Norrbottnian congenital insensitivity to pain.

Authors:  Jan K Minde
Journal:  Acta Orthop Suppl       Date:  2006-04

6.  Middle to long-term results of distal femoral tension band hemiepiphysiodesis in the treatment of idiopathic genu valgum.

Authors:  Soroush Baghdadi; S M Javad Mortazavi; Kamel Dastoureh; Alireza Moharrami; Taghi Baghdadi
Journal:  J Pediatr Orthop B       Date:  2021-01       Impact factor: 1.041

Review 7.  Congenital insensitivity to pain with anhidrosis (hereditary sensory and autonomic neuropathy type IV)

Authors:  S Rosemberg; S K Marie; S Kliemann
Journal:  Pediatr Neurol       Date:  1994-07       Impact factor: 3.372

8.  Clinical, pathological and genetic characterization of hereditary sensory and autonomic neuropathy type 1 (HSAN I).

Authors:  Henry Houlden; Rosalind King; Julian Blake; Mike Groves; Seth Love; Cathy Woodward; Simon Hammans; James Nicoll; Graham Lennox; Dominic G O'Donovan; Carolyn Gabriel; P K Thomas; Mary M Reilly
Journal:  Brain       Date:  2005-12-19       Impact factor: 13.501

9.  Natural history and biomarkers in hereditary sensory neuropathy type 1.

Authors:  Vera Fridman; Anne Louise Oaklander; William S David; Elise A Johnson; Jessica Pan; Peter Novak; Robert H Brown; Florian S Eichler
Journal:  Muscle Nerve       Date:  2015-02-11       Impact factor: 3.217

10.  The Orthopedic Manifestations of Congenital Insensitivity to Pain: A Population-based Study.

Authors:  Maximillian Mifsud; Michelle Spiteri; Karl Camilleri; Matthew Bonello; Thomas Azzopardi; Massimo Abela
Journal:  Indian J Orthop       Date:  2019 Sep-Oct       Impact factor: 1.251

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