Literature DB >> 33705168

Impact of treatment improvement on long-term anxiety: Results from CAMS and CAMELS.

Margaret E Crane1, Lesley A Norris1, Hannah E Frank1, Joshua Klugman2, Golda S Ginsburg3, Courtney Keeton4, Anne Marie Albano5, John Piacentini6, Tara S Peris3, Scott N Compton6, Dara Sakolsky3, Boris Birmaher3, Philip C Kendall1.   

Abstract

OBJECTIVE: This article examined associations between change in youth and family characteristics during youth anxiety treatment and long-term anxiety severity and overall functioning.
METHOD: Participants (N = 488; age 7-17 years; 45% male; 82% white) were randomized to 12 weeks of cognitive behavioral therapy (Coping Cat), medication (sertraline), their combination, or pill placebo in the Child/Adolescent Anxiety Multimodal Study (CAMS). A subset participated in the naturalistic follow-up Child/Adolescent Anxiety Multimodal Extended Long-term Study (CAMELS; n = 319; 3.70-11.83 years post-treatment). The current secondary analyses examined how change in anxiety severity (Child Global Impression-Severity), overall functioning (Children's Global Assessment Scale), caregiver psychopathology (Brief Symptom Inventory), caregiver strain (Family Burden Assessment Scale), and family dysfunction (Brief Family Assessment Measure) during CAMS was associated with anxiety severity and overall functioning years later (M = 7.72 years). CAMS procedures were registered on clinialtrials.gov.
RESULTS: Improvements in factors related to functioning (i.e., overall functioning, family dysfunction, caregiver strain) were associated with improvements in anxiety severity in CAMELS (|βys| ≥ .04, ps ≤ .04). Improvements in factors related to psychopathology (i.e., anxiety severity, caregiver psychopathology) were associated with improvements in overall functioning in CAMELS (|βys| ≥ .23, ps ≤ .04). It was changes in each of the variables examined (rather than baseline values) that predicted anxiety severity and overall functioning.
CONCLUSIONS: Both youth and family factors play a significant role in long-term treatment outcomes. Therapists would be wise to monitor how these factors change throughout treatment. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

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Year:  2021        PMID: 33705168      PMCID: PMC7959050          DOI: 10.1037/ccp0000523

Source DB:  PubMed          Journal:  J Consult Clin Psychol        ISSN: 0022-006X


  21 in total

1.  Anxiety and risk for substance dependence among late adolescents/young adults.

Authors:  Barbara Lopez; R Jay Turner; Lissette M Saavedra
Journal:  J Anxiety Disord       Date:  2005

2.  Familial predictors of treatment outcome in childhood anxiety disorders.

Authors:  A M Crawford; K Manassis
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2001-10       Impact factor: 8.829

3.  Childhood diagnoses and later risk for multiple suicide attempts.

Authors:  M David Rudd; Thomas E Joiner; Harold Rumzek
Journal:  Suicide Life Threat Behav       Date:  2004

4.  Evaluation of the clinical global impression scale among individuals with social anxiety disorder.

Authors:  T I Zaider; R G Heimberg; D M Fresco; F R Schneier; M R Liebowitz
Journal:  Psychol Med       Date:  2003-05       Impact factor: 7.723

5.  A children's global assessment scale (CGAS).

Authors:  D Shaffer; M S Gould; J Brasic; P Ambrosini; P Fisher; H Bird; S Aluwahlia
Journal:  Arch Gen Psychiatry       Date:  1983-11

6.  Child anxiety treatment: outcomes in adolescence and impact on substance use and depression at 7.4-year follow-up.

Authors:  Philip C Kendall; Scott Safford; Ellen Flannery-Schroeder; Alicia Webb
Journal:  J Consult Clin Psychol       Date:  2004-04

7.  Naturalistic follow-up of youths treated for pediatric anxiety disorders.

Authors:  Golda S Ginsburg; Emily M Becker; Courtney P Keeton; Dara Sakolsky; John Piacentini; Anne Marie Albano; Scott N Compton; Satish Iyengar; Kevin Sullivan; Nicole Caporino; Tara Peris; Boris Birmaher; Moira Rynn; John March; Philip C Kendall
Journal:  JAMA Psychiatry       Date:  2014-03       Impact factor: 21.596

8.  Parental psychopathology and treatment outcome for anxious youth: roles of family functioning and caregiver strain.

Authors:  Jessica L Schleider; Golda S Ginsburg; Courtney P Keeton; John R Weisz; Boris Birmaher; Phillip C Kendall; John Piacentini; Joel Sherrill; John T Walkup
Journal:  J Consult Clin Psychol       Date:  2014-09-15

9.  Results From the Child/Adolescent Anxiety Multimodal Extended Long-Term Study (CAMELS): Primary Anxiety Outcomes.

Authors:  Golda S Ginsburg; Emily M Becker-Haimes; Courtney Keeton; Philip C Kendall; Satish Iyengar; Dara Sakolsky; Anne Marie Albano; Tara Peris; Scott N Compton; John Piacentini
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2018-05-09       Impact factor: 8.829

10.  Child/Adolescent Anxiety Multimodal Study (CAMS): rationale, design, and methods.

Authors:  Scott N Compton; John T Walkup; Anne Marie Albano; John C Piacentini; Boris Birmaher; Joel T Sherrill; Golda S Ginsburg; Moira A Rynn; James T McCracken; Bruce D Waslick; Satish Iyengar; Phillip C Kendall; John S March
Journal:  Child Adolesc Psychiatry Ment Health       Date:  2010-01-05       Impact factor: 3.033

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