Literature DB >> 33704737

Immunotyping and Quantification of Melanoma Tumor-Infiltrating Lymphocytes.

Max O Meneveau1, Zeyad T Sahli1, Kevin T Lynch1, Ileana S Mauldin1, Craig L Slingluff2.   

Abstract

The density of tumour-infiltrating lymphocytes (TILs) in melanoma is correlated with improved clinical prognosis; however, standardized TIL immunotyping and quantification protocols are lacking. Herein, we provide a review of the technologies being utilized for the immunotyping and quantification of melanoma TILs.

Entities:  

Keywords:  Immunofluorescence histology; Immunotyping; Melanoma; Quantification; Time of flight mass cytometry; Tumor-infiltrating lymphocyte

Mesh:

Year:  2021        PMID: 33704737     DOI: 10.1007/978-1-0716-1205-7_36

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  58 in total

1.  A high number of tumor-infiltrating lymphocytes are associated with a small tumor size, low tumor stage, and a favorable prognosis in operated small cell lung carcinoma.

Authors:  A K Eerola; Y Soini; P Pääkkö
Journal:  Clin Cancer Res       Date:  2000-05       Impact factor: 12.531

2.  Nivolumab in previously untreated melanoma without BRAF mutation.

Authors:  Caroline Robert; Georgina V Long; Benjamin Brady; Caroline Dutriaux; Michele Maio; Laurent Mortier; Jessica C Hassel; Piotr Rutkowski; Catriona McNeil; Ewa Kalinka-Warzocha; Kerry J Savage; Micaela M Hernberg; Celeste Lebbé; Julie Charles; Catalin Mihalcioiu; Vanna Chiarion-Sileni; Cornelia Mauch; Francesco Cognetti; Ana Arance; Henrik Schmidt; Dirk Schadendorf; Helen Gogas; Lotta Lundgren-Eriksson; Christine Horak; Brian Sharkey; Ian M Waxman; Victoria Atkinson; Paolo A Ascierto
Journal:  N Engl J Med       Date:  2014-11-16       Impact factor: 91.245

3.  Multiplex Quantitative Analysis of Tumor-Infiltrating Lymphocytes and Immunotherapy Outcome in Metastatic Melanoma.

Authors:  Pok Fai Wong; Wei Wei; James W Smithy; Balazs Acs; Maria I Toki; Kim R M Blenman; Daniel Zelterman; Harriet M Kluger; David L Rimm
Journal:  Clin Cancer Res       Date:  2019-01-07       Impact factor: 12.531

4.  Tumor-infiltrating lymphocyte grade is an independent predictor of sentinel lymph node status and survival in patients with cutaneous melanoma.

Authors:  Farhad Azimi; Richard A Scolyer; Pavlina Rumcheva; Marc Moncrieff; Rajmohan Murali; Stanley W McCarthy; Robyn P Saw; John F Thompson
Journal:  J Clin Oncol       Date:  2012-06-18       Impact factor: 44.544

5.  Type, density, and location of immune cells within human colorectal tumors predict clinical outcome.

Authors:  Jérôme Galon; Anne Costes; Fatima Sanchez-Cabo; Amos Kirilovsky; Bernhard Mlecnik; Christine Lagorce-Pagès; Marie Tosolini; Matthieu Camus; Anne Berger; Philippe Wind; Franck Zinzindohoué; Patrick Bruneval; Paul-Henri Cugnenc; Zlatko Trajanoski; Wolf-Herman Fridman; Franck Pagès
Journal:  Science       Date:  2006-09-29       Impact factor: 47.728

6.  Tumor microenvironment of metastasis in human breast carcinoma: a potential prognostic marker linked to hematogenous dissemination.

Authors:  Brian D Robinson; Gabriel L Sica; Yi-Fang Liu; Thomas E Rohan; Frank B Gertler; John S Condeelis; Joan G Jones
Journal:  Clin Cancer Res       Date:  2009-03-24       Impact factor: 12.531

7.  Tumor infiltrating lymphocytes in lymph node melanoma metastases: a histopathologic prognostic indicator and an expression of local immune response.

Authors:  M C Mihm; C G Clemente; N Cascinelli
Journal:  Lab Invest       Date:  1996-01       Impact factor: 5.662

8.  Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma.

Authors:  Omid Hamid; Caroline Robert; Adil Daud; F Stephen Hodi; Wen-Jen Hwu; Richard Kefford; Jedd D Wolchok; Peter Hersey; Richard W Joseph; Jeffrey S Weber; Roxana Dronca; Tara C Gangadhar; Amita Patnaik; Hassane Zarour; Anthony M Joshua; Kevin Gergich; Jeroen Elassaiss-Schaap; Alain Algazi; Christine Mateus; Peter Boasberg; Paul C Tumeh; Bartosz Chmielowski; Scot W Ebbinghaus; Xiaoyun Nicole Li; S Peter Kang; Antoni Ribas
Journal:  N Engl J Med       Date:  2013-06-02       Impact factor: 91.245

9.  Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer.

Authors:  Lin Zhang; Jose R Conejo-Garcia; Dionyssios Katsaros; Phyllis A Gimotty; Marco Massobrio; Giorgia Regnani; Antonis Makrigiannakis; Heidi Gray; Katia Schlienger; Michael N Liebman; Stephen C Rubin; George Coukos
Journal:  N Engl J Med       Date:  2003-01-16       Impact factor: 91.245

10.  Efficacy of novel immunotherapy regimens in patients with metastatic melanoma with germline CDKN2A mutations.

Authors:  Hildur Helgadottir; Paola Ghiorzo; Remco van Doorn; Susana Puig; Max Levin; Richard Kefford; Martin Lauss; Paola Queirolo; Lorenza Pastorino; Ellen Kapiteijn; Miriam Potrony; Cristina Carrera; Håkan Olsson; Veronica Höiom; Göran Jönsson
Journal:  J Med Genet       Date:  2018-10-05       Impact factor: 6.318

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