Literature DB >> 33704728

Detection of Melanoma Cells in Lymphatic Drainage (LD) After Lymph Nodes Dissection Via Nested RT-PCR Analysis of Molecular Melanocytic Markers.

Aleksandra Gos1, Piotr Rutkowski2, Janusz A Siedlecki1.   

Abstract

We present the assay based on multimarker analysis of mRNA transcripts associated with melanocytic cells detected in lymphatic fluid collected after lymph node dissection. Positive results of reverse transcriptase polymerase chain reaction (RT-PCR) test have a strong relationship with melanoma recurrence and disease-specific survival time in stage III melanoma.

Entities:  

Keywords:  Lymph node metastases; Lymphatic drainage; Melanoma; RT-PCR

Mesh：

Substances：

Year:  2021        PMID： 33704728     DOI： 10.1007/978-1-0716-1205-7_27

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  4 in total

1.  A meta-analysis of reverse transcriptase-polymerase chain reaction for tyrosinase mRNA as a marker for circulating tumor cells in cutaneous melanoma.

Authors:  H Tsao; U Nadiminti; A J Sober; M Bigby
Journal:  Arch Dermatol       Date:  2001-03

2.  Multimarker reverse transcriptase-polymerase chain reaction assay in lymphatic drainage and sentinel node tumor burden.

Authors:  Piotr Rutkowski; Zbigniew I Nowecki; Alexander C J van Akkooi; Jadwiga Kulik; Michej Wanda; Janusz A Siedlecki; Alexander M M Eggermont; Wlodzimierz Ruka
Journal:  Ann Surg Oncol       Date:  2010-07-07       Impact factor: 5.344

3.  Molecular staging by multimarker reverse transcriptase-polymerase chain reaction assay of lymphatic drainage and blood from melanoma patients after lymph node dissection.

Authors:  Piotr Rutkowski; Zbigniew I Nowecki; Jadwiga Kulik; Wlodzimierz Ruka; Janusz A Siedlecki
Journal:  Melanoma Res       Date:  2008-08       Impact factor: 3.599

4.  Molecular and biochemical testing in stage III melanoma: multimarker reverse transcriptase-polymerase chain reaction assay of lymph fluid after lymph node dissection and preoperative serum lactate dehydrogenase level.

Authors:  Z I Nowecki; P Rutkowski; J Kulik; J A Siedlecki; W Ruka
Journal:  Br J Dermatol       Date:  2008-07-04       Impact factor: 9.302
  4 in total

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