Literature DB >> 3369481

Diaphragm insertion increases human vaginal oxygen tension.

G Wagner1, R J Levin, L Bohr.   

Abstract

The normal insertion of a contraceptive diaphragm into the vagina of five young women induced a dramatic increase in the vaginal oxygen tension (131 +/- 13 mm Hg, mean +/- SD, n = 5), which slowly fell at an initial rate of 0.9 +/- 0.2 mm Hg/min. Withdrawal of the diaphragm immediately restored vaginal oxygen tension to the normal hypoxic state (11 +/- 12 mm Hg). The change in gaseous equilibrium created by the trapped air of the diaphragm could have significant actions on the microbial activity and balance of the vagina.

Entities:  

Keywords:  Barrier Methods; Biology; Contraception; Contraceptive Methods; Cytologic Effects; Denmark; Developed Countries; Diseases; Europe; Examinations And Diagnoses; Family Planning; Genital Effects, Female; Genitalia; Genitalia, Female; Histochemical Effects; Infections; Insertion; Northern Europe; Physiology; Research Report; Scandinavia; Toxic Shock Syndrome; Treatment; Urogenital System; Vaginal Barrier Methods; Vaginal Diaphragm

Mesh:

Substances:

Year:  1988        PMID: 3369481     DOI: 10.1016/0002-9378(88)90214-1

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  6 in total

1.  Vaginal Staphylococcus aureus superantigen profile shift from 1980 and 1981 to 2003, 2004, and 2005.

Authors:  Patrick M Schlievert; Laura C Case; Kristi L Strandberg; Timothy J Tripp; Ying-Chi Lin; Marnie L Peterson
Journal:  J Clin Microbiol       Date:  2007-05-30       Impact factor: 5.948

2.  Cervicovaginal fluid and semen block the microbicidal activity of hydrogen peroxide produced by vaginal lactobacilli.

Authors:  Deirdre E O'Hanlon; Blair R Lanier; Thomas R Moench; Richard A Cone
Journal:  BMC Infect Dis       Date:  2010-05-19       Impact factor: 3.090

3.  Murine vaginal colonization model for investigating asymptomatic mucosal carriage of Streptococcus pyogenes.

Authors:  Michael E Watson; Hailyn V Nielsen; Scott J Hultgren; Michael G Caparon
Journal:  Infect Immun       Date:  2013-03-04       Impact factor: 3.441

4.  The implausible "in vivo" role of hydrogen peroxide as an antimicrobial factor produced by vaginal microbiota.

Authors:  Gilda Tachedjian; Deirdre E O'Hanlon; Jacques Ravel
Journal:  Microbiome       Date:  2018-02-06       Impact factor: 14.650

5.  Vaginal pH and microbicidal lactic acid when lactobacilli dominate the microbiota.

Authors:  Deirdre E O'Hanlon; Thomas R Moench; Richard A Cone
Journal:  PLoS One       Date:  2013-11-06       Impact factor: 3.240

6.  Vaginal pH measured in vivo: lactobacilli determine pH and lactic acid concentration.

Authors:  Deirdre Elizabeth O'Hanlon; Richard A Come; Thomas R Moench
Journal:  BMC Microbiol       Date:  2019-01-14       Impact factor: 3.605

  6 in total

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