| Literature DB >> 33692925 |
Ankit Rai1, Bhargav Gajula1, Navin Kumar1, Akanksha Malik2,3.
Abstract
Gastrointestinal (GI) tract perforation is a surgical emergency. The epidemiology and etiology of perforation vary considerably across geography. Lower GI tract perforations in the elderly predominate in the West compared to upper GI perforations in the younger population in the tropics. Fungi and viruses have been reported to cause GI perforations in immuno-compromised individuals but it is rare in immuno-competent individuals. We report a very rare case of gastric perforation secondary to fungal gastritis in an immuno-competent 35-year-old female who presented with features of peritonitis. At emergency laparotomy, gastric perforation was found which was repaired by the Cellan-Jones method. Perforation edge biopsy findings were consistent with fungal etiology. She responded well to Antifungal therapy. We conclude that fungal etiology can be considered in patients with gastric perforation without any history of peptic ulcer disease (PUD) or use of oral non-steroidal anti-inflammatory drugs.Entities:
Keywords: gastric pathology; gastric perforation by fungal colonization; invasive fungal infections; mucormycosis induced gastric perforation
Year: 2021 PMID: 33692925 PMCID: PMC7937405 DOI: 10.7759/cureus.13156
Source DB: PubMed Journal: Cureus ISSN: 2168-8184