Xiaohua Wang1, Qingsong Lai2, Baoqing Zheng1, Li Ye1, Si Wen1, Yunling Yan1, Bin Yang1, Mao-Qiang Man1. 1. Dermatology Hospital, Southern Medical University, Guangdong, 510091, People's Republic of China. 2. Center for Chronic Disease Prevention and Control of Puning City, Puning, Guangdong, 515300, People's Republic of China.
Abstract
BACKGROUND: Although the characteristics of pruritus in some skin diseases are documented, characteristics of pruritus related to gender-, age-, and skin disorder have not yet been well defined. OBJECTIVE: To characterize dermatosis-associated pruritus in Chinese patients. METHODS: A cross-sectional study was carried out in a single center. The intensity of pruritus was evaluated using a 0-10 visual analog scale (VAS). Skin disorders were diagnosed by dermatologists. The prevalence and intensity of pruritus were compared among skin disorders, and between males and females. RESULTS: Valid questionnaires were obtained from 1,246 female and 864 male patients. Patients with acne, eczematous dermatitis, and urticaria accounted for 18%, 17%, and 14%, respectively. Both the prevalence and severity of pruritus varied greatly with skin disorders (p<0.0001). Patients with either urticaria or eczematous dermatitis displayed a higher prevalence of pruritus (92% and 82%, respectively), while subjects with urticaria exhibited the highest VAS in comparison to those with other skin disorders (p<0.05 to p<0.001 vs the others). Moreover, both the prevalence and severity of pruritus were positively associated with age in both males and females (p<0.0001). Furthermore, 60 out of 77 patients (78%) with topical glucocorticoid-induced dermatitis experienced pruritus, with a VAS of 2.03±0.21. Finally, a lower VAS was found in subjects with oily skin than those with either dry or normal skin. CONCLUSION: The prevalence and severity of pruritus vary with skin disorders, skin type, age, and gender in Chinese patients.
BACKGROUND: Although the characteristics of pruritus in some skin diseases are documented, characteristics of pruritus related to gender-, age-, and skin disorder have not yet been well defined. OBJECTIVE: To characterize dermatosis-associated pruritus in Chinese patients. METHODS: A cross-sectional study was carried out in a single center. The intensity of pruritus was evaluated using a 0-10 visual analog scale (VAS). Skin disorders were diagnosed by dermatologists. The prevalence and intensity of pruritus were compared among skin disorders, and between males and females. RESULTS: Valid questionnaires were obtained from 1,246 female and 864 male patients. Patients with acne, eczematous dermatitis, and urticaria accounted for 18%, 17%, and 14%, respectively. Both the prevalence and severity of pruritus varied greatly with skin disorders (p<0.0001). Patients with either urticaria or eczematous dermatitis displayed a higher prevalence of pruritus (92% and 82%, respectively), while subjects with urticaria exhibited the highest VAS in comparison to those with other skin disorders (p<0.05 to p<0.001 vs the others). Moreover, both the prevalence and severity of pruritus were positively associated with age in both males and females (p<0.0001). Furthermore, 60 out of 77 patients (78%) with topical glucocorticoid-induced dermatitis experienced pruritus, with a VAS of 2.03±0.21. Finally, a lower VAS was found in subjects with oily skin than those with either dry or normal skin. CONCLUSION: The prevalence and severity of pruritus vary with skin disorders, skin type, age, and gender in Chinese patients.
Authors: Christina Schut; Florence J Dalgard; Jon Anders Halvorsen; Uwe Gieler; Lars Lien; Lucía Tomas Aragones; Françoise Poot; Gregor B E Jemec; Laurent Misery; Lajos Kemény; Francesca Sampogna; Henriët van Middendorp; Flora Balieva; Dennis Linder; Jacek C Szepietowski; Andrey Lvov; Servando E Marron; Ilknur K Altunay; Andrew Y Finlay; Sam Salek; Jörg Kupfer Journal: Acta Derm Venereol Date: 2019-02-01 Impact factor: 4.437
Authors: Mao-Qiang Man; Tzu-Kai Lin; Juan L Santiago; Anna Celli; Lily Zhong; Zhi-Ming Huang; Truus Roelandt; Melanie Hupe; John P Sundberg; Kathleen A Silva; Debra Crumrine; Gemma Martin-Ezquerra; Carles Trullas; Richard Sun; Joan S Wakefield; Maria L Wei; Kenneth R Feingold; Theodora M Mauro; Peter M Elias Journal: J Invest Dermatol Date: 2014-04-14 Impact factor: 8.551