Literature DB >> 33689074

Thermovaccination: Thermoheliox as an Immune Response Stimulant. Kinetics of Antibodies and C-Reactive Protein Synthesis in Coronaviral Infection.

S D Varfolomeev1,2, S V Zhuravel3, A A Panin4, L V Shogenova5, V I Bykov2, S B Tsybenova6, A M Ryabokon2, I I Utkina3, P V Gavrilov3, A G Chuchalin5.   

Abstract

The high efficiency of using thermoheliox (inhalation with a high-temperature mixture of helium and oxygen) in the treatment of patients affected by COVID-19 was shown. The dynamics of accumulation of IgG, IgM, and C-reactive protein (CRP) in patients with coronavirus infection in the "working" and control groups was studied experimentally. It was shown that thermoheliox intensifies the synthesis of IgG, IgM, and CRP antibodies, while eliminating the induction period on the kinetic curves of the synthesis of specific antibodies in the IgG form and transfers the synthesis of CRP to a fast phase. The results of experiments confirm the previously obtained data based on the analysis of the kinetic model of the development of coronaviral infection in the human body.

Entities:  

Keywords:  C-reactive protein; coronavirus; immunoglobulin G; immunoglobulin M; kinetic model; thermoheliox; thermovaccination

Year:  2021        PMID: 33689074     DOI: 10.1134/S1607672921010129

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN: 1607-6729            Impact factor:   0.788


  9 in total

1.  Antibody responses to SARS-CoV-2 in patients with COVID-19.

Authors:  Quan-Xin Long; Bai-Zhong Liu; Hai-Jun Deng; Gui-Cheng Wu; Kun Deng; Yao-Kai Chen; Pu Liao; Jing-Fu Qiu; Yong Lin; Xue-Fei Cai; De-Qiang Wang; Yuan Hu; Ji-Hua Ren; Ni Tang; Yin-Yin Xu; Li-Hua Yu; Zhan Mo; Fang Gong; Xiao-Li Zhang; Wen-Guang Tian; Li Hu; Xian-Xiang Zhang; Jiang-Lin Xiang; Hong-Xin Du; Hua-Wen Liu; Chun-Hui Lang; Xiao-He Luo; Shao-Bo Wu; Xiao-Ping Cui; Zheng Zhou; Man-Man Zhu; Jing Wang; Cheng-Jun Xue; Xiao-Feng Li; Li Wang; Zhi-Jie Li; Kun Wang; Chang-Chun Niu; Qing-Jun Yang; Xiao-Jun Tang; Yong Zhang; Xia-Mao Liu; Jin-Jing Li; De-Chun Zhang; Fan Zhang; Ping Liu; Jun Yuan; Qin Li; Jie-Li Hu; Juan Chen; Ai-Long Huang
Journal:  Nat Med       Date:  2020-04-29       Impact factor: 53.440

2.  The embryonic origin of endocrine cells of the gastrointestinal tract.

Authors:  A Andrew; B Kramer; B B Rawdon
Journal:  Gen Comp Endocrinol       Date:  1982-06       Impact factor: 2.822

Review 3.  Clinical Trials of Repurposed Antivirals for SARS-CoV-2.

Authors:  Miguel Angel Martinez
Journal:  Antimicrob Agents Chemother       Date:  2020-08-20       Impact factor: 5.191

Review 4.  The Role of Cytokines including Interleukin-6 in COVID-19 induced Pneumonia and Macrophage Activation Syndrome-Like Disease.

Authors:  Dennis McGonagle; Kassem Sharif; Anthony O'Regan; Charlie Bridgewood
Journal:  Autoimmun Rev       Date:  2020-04-03       Impact factor: 9.754

5.  Insights into the Use of C-Reactive Protein as a Diagnostic Index of Disease Severity in COVID-19 Infections.

Authors:  Lawrence A Potempa; Ibraheem M Rajab; Peter C Hart; Jose Bordon; Rafael Fernandez-Botran
Journal:  Am J Trop Med Hyg       Date:  2020-06-25       Impact factor: 2.345

6.  Chemical kinetics of the development of coronaviral infection in the human body: Critical conditions, toxicity mechanisms, "thermoheliox", and "thermovaccination".

Authors:  Sergey D Varfolomeev; Alexander A Panin; Valeriy I Bykov; Svetlana B Tsybenova; Alexander G Chuchalin
Journal:  Chem Biol Interact       Date:  2020-08-01       Impact factor: 5.192

  9 in total

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