Literature DB >> 33686020

β cell aging and age-related diabetes.

Min Zhu1, Xiaohong Liu1, Wen Liu1, Yanrong Lu1, Jingqiu Cheng1,2, Younan Chen1,2.   

Abstract

Type 2 diabetes is characterized by insulin resistance and loss of β cell mass and function. Aging is considered as a major risk factor for development of type 2 diabetes. However, the roles of pancreatic β cell senescence and systemic aging in the pathogenesis of type 2 diabetes in elderly people remain poorly understood. In this review, we aimed to discuss the current findings and viewpoints focusing on β cell aging and the development of type 2 diabetes.

Entities:  

Keywords:  age-related diabetes; aging; type 2 diabetes (T2D); β cell function; β cell senescence

Year:  2021        PMID： 33686020      PMCID： PMC7993693          DOI： 10.18632/aging.202593

Source DB:  PubMed          Journal:  Aging (Albany NY)        ISSN： 1945-4589            Impact factor:   5.682


  99 in total

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Authors:  Joan K Bardsley; Laura L Want
Journal:  Crit Care Nurs Q       Date:  2004 Apr-Jun

2.  The occurrence of islet amyloid polypeptide amyloidosis in Japanese subjects.

Authors:  Yu Su; Yohei Misumi; Mitsuharu Ueda; Makoto Shono; Masayoshi Tasaki; Jianying Guo; Hirofumi Jono; Konen Obayashi; Takafumi Senokuchi; Kazuya Yamagata; Yukio Ando
Journal:  Pancreas       Date:  2012-08       Impact factor: 3.327

Review 3.  Overview of the pancreas.

Authors:  Po Sing Leung
Journal:  Adv Exp Med Biol       Date:  2010       Impact factor: 2.622

Review 4.  The β-cell assassin: IAPP cytotoxicity.

Authors:  Daniel Raleigh; Xiaoxue Zhang; Benoît Hastoy; Anne Clark
Journal:  J Mol Endocrinol       Date:  2017-08-15       Impact factor: 5.098

5.  Prevalence and Ethnic Pattern of Diabetes and Prediabetes in China in 2013.

Authors:  Limin Wang; Pei Gao; Mei Zhang; Zhengjing Huang; Dudan Zhang; Qian Deng; Yichong Li; Zhenping Zhao; Xueying Qin; Danyao Jin; Maigeng Zhou; Xun Tang; Yonghua Hu; Linhong Wang
Journal:  JAMA       Date:  2017-06-27       Impact factor: 56.272

6.  Age-Dependent Decline in the Coordinated [Ca2+] and Insulin Secretory Dynamics in Human Pancreatic Islets.

Authors:  Matthew J Westacott; Nikki L Farnsworth; Joshua R St Clair; Greg Poffenberger; Audrey Heintz; Nurin W Ludin; Nathaniel J Hart; Alvin C Powers; Richard K P Benninger
Journal:  Diabetes       Date:  2017-06-06       Impact factor: 9.461

7.  Increased islet apoptosis in Pdx1+/- mice.

Authors:  James D Johnson; Noreen T Ahmed; Dan S Luciani; Zhiqiang Han; Hung Tran; Jun Fujita; Stanley Misler; Helena Edlund; Kenneth S Polonsky
Journal:  J Clin Invest       Date:  2003-04       Impact factor: 14.808

Review 8.  Cellular senescence in aging and age-related disease: from mechanisms to therapy.

Authors:  Bennett G Childs; Matej Durik; Darren J Baker; Jan M van Deursen
Journal:  Nat Med       Date:  2015-12       Impact factor: 53.440

9.  Impaired islet turnover in human donor pancreata with aging.

Authors:  Christina Reers; Saskia Erbel; Irene Esposito; Bruno Schmied; Markus W Büchler; Peter P Nawroth; Robert A Ritzel
Journal:  Eur J Endocrinol       Date:  2008-11-12       Impact factor: 6.664

10.  Mitochondrial reactive oxygen species are obligatory signals for glucose-induced insulin secretion.

Authors:  Corinne Leloup; Cécile Tourrel-Cuzin; Christophe Magnan; Melis Karaca; Julien Castel; Lionel Carneiro; Anne-Laure Colombani; Alain Ktorza; Louis Casteilla; Luc Pénicaud
Journal:  Diabetes       Date:  2008-12-10       Impact factor: 9.461
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  6 in total

1.  Altered Nutrient Uptake Causes Mitochondrial Dysfunction in Senescent CD8+ EMRA T Cells During Type 2 Diabetes.

Authors:  Lauren A Callender; Elizabeth C Carroll; Conor Garrod-Ketchley; Johannes Schroth; Jonas Bystrom; Victoria Berryman; Melanie Pattrick; Desiree Campbell-Richards; Gillian A Hood; Graham A Hitman; Sarah Finer; Sian M Henson
Journal:  Front Aging       Date:  2021-08-13

Review 2.  Application of Mediterranean Diet in Cardiovascular Diseases and Type 2 Diabetes Mellitus: Motivations and Challenges.

Authors:  Najwa Salim AlAufi; Yoke Mun Chan; Mostafa I Waly; Yit Siew Chin; Barakatun-Nisak Mohd Yusof; Norliza Ahmad
Journal:  Nutrients       Date:  2022-07-05       Impact factor: 6.706

Review 3.  Lipid Droplets' Role in the Regulation of β-Cell Function and β-Cell Demise in Type 2 Diabetes.

Authors:  Xin Tong; Siming Liu; Roland Stein; Yumi Imai
Journal:  Endocrinology       Date:  2022-03-01       Impact factor: 5.051

Review 4.  Utilization of Mind-Body Intervention for Integrative Health Care of COVID-19 Patients and Survivors.

Authors:  Hyun-Jeong Yang; Noriko Setou; Eugene Koh
Journal:  Int J Environ Res Public Health       Date:  2022-05-29       Impact factor: 4.614

5.  β-Cell function and body mass index are predictors of exercise response in elderly patients with prediabetes.

Authors:  Yali He; Yanhong Feng; Junli Shi; Hong Tang; Linhui Chen; Qingqing Lou
Journal:  J Diabetes Investig       Date:  2022-06-20       Impact factor: 3.681

6.  Effect of Glycated Hemoglobin (HbA1c) and Duration of Disease on Lung Functions in Type 2 Diabetic Patients.

Authors:  Hawra Bin Maan; Sultan Ayoub Meo; Fawziah Al Rouq; Imran Muhammad Umar Meo; Milagros E Gacuan; Joud Mohammed Alkhalifah
Journal:  Int J Environ Res Public Health       Date:  2021-06-29       Impact factor: 3.390
  6 in total

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