Literature DB >> 33685562

Implementation of EMR-based standardized antibiotic desensitization protocols and its impact on providers.

Aarti Pandya1, Eric R Gregory2, Sheeba Cherian3, Sonya Parashar3, Selina Gierer3.   

Abstract

Background: As desensitization protocols become more readily available and published, more institutions are implementing them and searching for ways to streamline the process. There have been no published studies to date on the effect that electronic medical record systems (EMR) have on the safety and efficiency of β-lactam antibiotic desensitization. Objective: The purpose of this study was to evaluate the changes in workflow, efficiency, and medical errors after implementation of β-lactam antibiotic desensitization.
Methods: A collaborative effort between the Allergy/Immunology Division and the Pharmacy Department led to the creation and implementation of antibiotic desensitization order sets. Pre- and postimplementation of β-lactam antibiotic surveys were sent to pharmacists and allergy/immunology fellows and attendings at a single-center tertiary care center.
Results: There were only 26 valid respondents (12.3%) to both the pre- and postimplementation surveys. The percentage of respondents who thought that the time needed to prepare desensitization materials was < 4 hours increased from 23% to 77% (p < 0.001). The percentage of respondents who thought that the time needed to input electronic desensitization orders was < 1 hour increased from 19% to 54% (p = 0.002). The percentage of respondents who identified zero errors increased from 42% to 92% (p = 0.001). The perception of the overall desensitization process efficiency significantly increased (p < 0.001).
Conclusion: Creation of standardized electronic β-lactam antibiotic desensitization order sets significantly decreased the time taken to order and prepare materials and increased overall efficiency.

Entities:  

Year:  2021        PMID: 33685562      PMCID: PMC8133017          DOI: 10.2500/aap.2021.42.200115

Source DB:  PubMed          Journal:  Allergy Asthma Proc        ISSN: 1088-5412            Impact factor:   2.587


  19 in total

1.  Drug allergy: an updated practice parameter.

Authors: 
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2.  Successful desensitization in penicillin sensitivity.

Authors:  S M PECK; S SIEGAL; R BERGAMINI
Journal:  J Am Med Assoc       Date:  1947-08-30

3.  The use of standardized drug desensitization protocols at a pediatric institution.

Authors:  Malika Gupta; Jamie M Gomes; Jamie Irizarry; Sigrid Payne DaVeiga
Journal:  J Allergy Clin Immunol Pract       Date:  2016-12-27

4.  Evaluation of Pharmacy-Developed Antibiotic Desensitization Protocols.

Authors:  Xian Jie Cindy Chen; Karen Fong; Diana Altshuler; Yanina Dubrovskaya; Eddie Louie; Nancy Amoroso; Ronald Goldenberg; John Papadopoulos
Journal:  Ann Pharmacother       Date:  2018-09-20       Impact factor: 3.154

Review 5.  Diagnoses and Management of Drug Hypersensitivity and Anaphylaxis in Cancer and Chronic Inflammatory Diseases: Reactions to Taxanes and Monoclonal Antibodies.

Authors:  Rafael Bonamichi-Santos; Mariana Castells
Journal:  Clin Rev Allergy Immunol       Date:  2018-06       Impact factor: 8.667

Review 6.  Drug allergy.

Authors:  Paul A Greenberger
Journal:  Allergy Asthma Proc       Date:  2019-11-01       Impact factor: 2.587

Review 7.  Penicillin Allergy.

Authors:  Mariana Castells; David A Khan; Elizabeth J Phillips
Journal:  N Engl J Med       Date:  2019-12-12       Impact factor: 91.245

Review 8.  Desensitization in delayed drug hypersensitivity reactions -- an EAACI position paper of the Drug Allergy Interest Group.

Authors:  K Scherer; K Brockow; W Aberer; J H C Gooi; P Demoly; A Romano; B Schnyder; P Whitaker; J S R Cernadas; A J Bircher
Journal:  Allergy       Date:  2013-06-07       Impact factor: 13.146

Review 9.  Desensitization for drug allergy.

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Journal:  Curr Opin Allergy Clin Immunol       Date:  2006-12

Review 10.  Drug Hypersensitivity and Desensitizations: Mechanisms and New Approaches.

Authors:  Leticia de Las Vecillas Sánchez; Leila A Alenazy; Marlene Garcia-Neuer; Mariana C Castells
Journal:  Int J Mol Sci       Date:  2017-06-20       Impact factor: 5.923

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  2 in total

1.  Hereditary angioedema again revisited.

Authors:  Joseph A Bellanti; Russell A Settipane
Journal:  Allergy Asthma Proc       Date:  2021-03-01       Impact factor: 2.587

Review 2.  The Use of Electronic Health Records to Study Drug-Induced Hypersensitivity Reactions from 2000 to 2021: A Systematic Review.

Authors:  Fatima Bassir; Sheril Varghese; Liqin Wang; Yen Po Chin; Li Zhou
Journal:  Immunol Allergy Clin North Am       Date:  2022-03-31       Impact factor: 3.152

  2 in total

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