Toshiaki Goda1, Naoki Oyama2, Takanori Iwamoto2, Hiroki Takai3, Shunji Matsubara3, Masaaki Uno3, Yoshiki Yagita2. 1. Department of Stroke Medicine, Kawasaki Medical School, Matsushima, Kurashiki, Okayama, 577701-0192, Japan. to4aki.5da.takaraduka@gmail.com. 2. Department of Stroke Medicine, Kawasaki Medical School, Matsushima, Kurashiki, Okayama, 577701-0192, Japan. 3. Department of Neurosurgery, Kawasaki Medical School, Okayama, Japan.
Abstract
BACKGROUND: Isolated basilar artery dissection (IBAD) is a rare but important cause of ischemic stroke. Anti-thrombotic therapy is often used to treat IBAD-related ischemic stroke, but selected cases might need more aggressive treatment. There is no previous report of emergent stenting for IBAD-related ischemic stroke after intravenous thrombolysis. CASE PRESENTATION: A 53-year-old Japanese woman was admitted to our hospital with disturbance of consciousness, right hemiplegia, severe dysarthria, and total gaze paralysis. Brain magnetic resonance imaging revealed no ischemic lesion, but magnetic resonance angiography showed stenosis in the basilar artery. After initiation of intravenous thrombolysis, her neurological symptoms dramatically improved. Five hours later, however, her symptoms deteriorated again. Cerebral angiography showed IBAD. Emergent stenting was successfully performed. At 90 days after stroke onset, she had no significant disability, with a modified Rankin scale score of 1. CONCLUSIONS: Emergent stenting can be an effective treatment for patients with IBAD-related ischemic stroke who are resistant to IV-rtPA.
BACKGROUND: Isolated basilar artery dissection (IBAD) is a rare but important cause of ischemic stroke. Anti-thrombotic therapy is often used to treat IBAD-related ischemic stroke, but selected cases might need more aggressive treatment. There is no previous report of emergent stenting for IBAD-related ischemic stroke after intravenous thrombolysis. CASE PRESENTATION: A 53-year-old Japanese woman was admitted to our hospital with disturbance of consciousness, right hemiplegia, severe dysarthria, and total gaze paralysis. Brain magnetic resonance imaging revealed no ischemic lesion, but magnetic resonance angiography showed stenosis in the basilar artery. After initiation of intravenous thrombolysis, her neurological symptoms dramatically improved. Five hours later, however, her symptoms deteriorated again. Cerebral angiography showed IBAD. Emergent stenting was successfully performed. At 90 days after stroke onset, she had no significant disability, with a modified Rankin scale score of 1. CONCLUSIONS: Emergent stenting can be an effective treatment for patients with IBAD-related ischemic stroke who are resistant to IV-rtPA.
Authors: M Ruecker; M Furtner; M Knoflach; P Werner; T Gotwald; A Chemelli; A Zangerle; B Prantl; B Matosević; C Schmidauer; E Schmutzhard; J Willeit; S Kiechl Journal: Cerebrovasc Dis Date: 2010-07-24 Impact factor: 2.762
Authors: B M Kim; S H Suh; S I Park; Y S Shin; E C Chung; M H Lee; E J Kim; J S Koh; H-S Kang; H G Roh; Y S Won; P-W Chung; Y-B Kim; B C Suh Journal: AJNR Am J Neuroradiol Date: 2008-08-07 Impact factor: 3.825