Literature DB >> 3368532

Exposure to light in healthy elderly subjects and Alzheimer's patients.

S S Campbell1, D F Kripke, J C Gillin, J C Hrubovcak.   

Abstract

Exposure to light was recorded from 10 healthy elderly adults and 13 age-matched subjects with senile dementia of the Alzheimer's type (SDAT). Data were recorded in the home, for an average of 5 days, while subjects continued their normal daily activities. Subjects were exposed to remarkably small intervals of illumination exceeding 2000 lux. Subjects with SDAT were exposed to bright light significantly less than healthy controls (0.5 vs. 1.0 hr). Whether or not they had SDAT, males were exposed to illumination exceeding 2000 lux significantly more than were females. Healthy elderly received about two-thirds the duration of bright light received by healthy younger subjects. These findings suggest an association between decreased exposure to bright light and the declines in sleep quality which typically accompany normal and pathological aging.

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Year:  1988        PMID: 3368532     DOI: 10.1016/0031-9384(88)90289-2

Source DB:  PubMed          Journal:  Physiol Behav        ISSN: 0031-9384


  45 in total

1.  Light exposure patterns in healthy older and young adults.

Authors:  Karine Scheuermaier; Alison M Laffan; Jeanne F Duffy
Journal:  J Biol Rhythms       Date:  2010-04       Impact factor: 3.182

2.  Responsiveness of the aging circadian clock to light.

Authors:  S Benloucif; K Green; M L'Hermite-Balériaux; S Weintraub; L F Wolfe; P C Zee
Journal:  Neurobiol Aging       Date:  2005-11-23       Impact factor: 4.673

3.  Decreased sensitivity to phase-delaying effects of moderate intensity light in older subjects.

Authors:  Jeanne F Duffy; Jamie M Zeitzer; Charles A Czeisler
Journal:  Neurobiol Aging       Date:  2006-04-18       Impact factor: 4.673

4.  Sleep and Its Disorders in Seniors.

Authors:  Carl J Stepnowsky; Sonia Ancoli-Israel
Journal:  Sleep Med Clin       Date:  2008

5.  Phase-shifting response to light in older adults.

Authors:  Seong Jae Kim; Susan Benloucif; Kathryn Jean Reid; Sandra Weintraub; Nancy Kennedy; Lisa F Wolfe; Phyllis C Zee
Journal:  J Physiol       Date:  2013-10-21       Impact factor: 5.182

6.  The effects of evening light exposure on the sleep of elderly women expressing sleep complaints.

Authors:  K M Cooke; M A Kreydatus; A Atherton; E B Thoman
Journal:  J Behav Med       Date:  1998-02

Review 7.  Light, sleep and circadian rhythms in older adults with Alzheimer's disease and related dementias.

Authors:  Mariana G Figueiro
Journal:  Neurodegener Dis Manag       Date:  2017-05-23

Review 8.  Use of sleep-promoting medications in nursing home residents : risks versus benefits.

Authors:  David K Conn; Robert Madan
Journal:  Drugs Aging       Date:  2006       Impact factor: 3.923

Review 9.  Light therapy and Alzheimer's disease and related dementia: past, present, and future.

Authors:  Nicholas Hanford; Mariana Figueiro
Journal:  J Alzheimers Dis       Date:  2013       Impact factor: 4.472

Review 10.  Sleep disturbances in patients with Alzheimer's disease: epidemiology, pathophysiology and treatment.

Authors:  M V Vitiello; S Borson
Journal:  CNS Drugs       Date:  2001       Impact factor: 5.749

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