Literature DB >> 33684453

Prevalence and drug use correlates of extra-medical use of prescription medications for sleep among adults in the United States: Results of the 2015-2018 National Survey on Drug Use and Health.

Catalina Lopez-Quintero1, Trey Warren2, Alyssa Falise3, Vinita Sharma4, Cristina Bares5, Assaf Oshri6.   

Abstract

BACKGROUND: This paper examines the epidemiology of extra-medical use of prescription medications for sleep among a nationally representative sample of U.S. adults.
METHODS: We analyzed data from the 2015-2018 National Surveys on Drug Use and Health. The sample includes 3410 U.S. adults who reported extra-medical use of prescription medications for sleep. Multinomial logistic regression models identified correlates of type of drug used [i.e., sedatives and/or tranquilizers-only (ST-only), prescription pain relievers-only (PPR-only), or sedatives, tranquilizers, and prescription pain relievers (ST + PPR)], and logistic regression models identified correlates of reasons for extra-medical use (i.e., sleep-only vs. sleep and recreational).
RESULTS: About 60% (95%CI = 58.9, 63.5) of the sample reported extra-medical use of ST-only, followed by PPR-only (29.9%, 95%CI = 27.5, 32.5), and ST + PPR (8.9%, 95%CI = 7.7, 10.4). Recreational use was reported by 28.4% (95% CI = 26.5, 30.4) of the sample. The odds of extra-medical use of PPR-only (aRRR = 3.1, 95%CI = 2.1, 4.5) and ST + PPR (aRRR = 1.9, 95%CI = 1.2, 3.1) as opposed to ST-only, were greater among Non-Hispanic Blacks than Non-Hispanic Whites. Compared to non-alcohol users, those with a past-12 months diagnosis of alcohol use disorder were more likely to use ST + PPR rather than ST-only (aIRR = 2.0, 95%CI = 1.1, 3.7). Non-Hispanic Blacks (aOR = 0.6, 95%CI = 0.4, 08) and individuals living in rural areas (aOR = 0.5, 95%CI = 0.3, 09) were less likely to report extra-medical use of prescription medications for recreational reasons than Non-Hispanic Whites and those residing in large metropolitan areas, respectively.
CONCLUSIONS: Extra-medical use of PPR-only and ST + PPR as an aid to sleep, is prevalent among Non-Hispanic Blacks, young adults, and those residing in rural areas. Most individuals reported that extra-medical use of prescription medications was primarily motivated by sleep reasons, rather than by sleep and recreational reasons. Potential interventions include access to sleep treatments, education on the effectiveness and risk associated with extra-medical use and co-use of prescription medications for sleep, and research on sleep-related disparities.
Copyright © 2021 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Misuse; Opioids; Pain relievers; Sedatives; Sleep; Tranquilizers

Mesh:

Substances:

Year:  2021        PMID: 33684453      PMCID: PMC8409243          DOI: 10.1016/j.pbb.2021.173169

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN: 0091-3057            Impact factor:   3.533


  41 in total

1.  Prevalence and Correlates of Benzodiazepine Use, Misuse, and Use Disorders Among Adults in the United States.

Authors:  Carlos Blanco; Beth Han; Christopher M Jones; Kimberly Johnson; Wilson M Compton
Journal:  J Clin Psychiatry       Date:  2018-10-16       Impact factor: 4.384

2.  Weighing the balance: how analgesics used in chronic pain influence sleep?

Authors:  Miqdad H Bohra; Chhavi Kaushik; Daniel Temple; Sharon A Chung; Colin M Shapiro
Journal:  Br J Pain       Date:  2014-08

3.  Prescription tranquilizer/sedative misuse prevalence and correlates across age cohorts in the US.

Authors:  Ty S Schepis; Christian J Teter; Linda Simoni-Wastila; Sean Esteban McCabe
Journal:  Addict Behav       Date:  2018-06-12       Impact factor: 3.913

4.  The effect of inmate populations on estimates of DSM-IV alcohol and drug use disorders in the United States.

Authors:  Wilson M Compton; Deborah Dawson; Sarah Q Duffy; Bridget F Grant
Journal:  Am J Psychiatry       Date:  2010-04       Impact factor: 18.112

5.  The epidemiology of benzodiazepine misuse: A systematic review.

Authors:  Victoria R Votaw; Rachel Geyer; Maya M Rieselbach; R Kathryn McHugh
Journal:  Drug Alcohol Depend       Date:  2019-05-07       Impact factor: 4.492

6.  Shifting characteristics of nonmedical prescription tranquilizer users in the United States, 2005-2014.

Authors:  Joseph J Palamar; Benjamin H Han; Silvia S Martins
Journal:  Drug Alcohol Depend       Date:  2018-12-08       Impact factor: 4.492

7.  The association between insomnia and prescription opioid use: results from a community sample in Northeast Florida.

Authors:  Mirsada Serdarevic; Vicki Osborne; Catherine W Striley; Linda B Cottler
Journal:  Sleep Health       Date:  2017-08-10

8.  Sleep-disordered breathing associated with long-term opioid therapy.

Authors:  Robert J Farney; James M Walker; Tom V Cloward; Steven Rhondeau
Journal:  Chest       Date:  2003-02       Impact factor: 9.410

Review 9.  Polydrug abuse: a review of opioid and benzodiazepine combination use.

Authors:  Jermaine D Jones; Shanthi Mogali; Sandra D Comer
Journal:  Drug Alcohol Depend       Date:  2012-08-02       Impact factor: 4.492

10.  Purposeful selection of variables in logistic regression.

Authors:  Zoran Bursac; C Heath Gauss; David Keith Williams; David W Hosmer
Journal:  Source Code Biol Med       Date:  2008-12-16
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