Literature DB >> 33682441

The Indiana O'Brien Center for Advanced Renal Microscopic Analysis.

Kenneth W Dunn1, Bruce A Molitoris1, Pierre C Dagher1.   

Abstract

The Indiana O'Brien Center for Advanced Microscopic Analysis is a National Institutes of Health (NIH) P30-funded research center dedicated to the development and dissemination of advanced methods of optical microscopy to support renal researchers throughout the world. The Indiana O'Brien Center was founded in 2002 as an NIH P-50 project with the original goal of helping researchers realize the potential of intravital multiphoton microscopy as a tool for understanding renal physiology and pathophysiology. The center has since expanded into the development and implementation of large-scale, high-content tissue cytometry. The advanced imaging capabilities of the center are made available to renal researchers worldwide via collaborations and a unique fellowship program. Center outreach is accomplished through an enrichment core that oversees a seminar series, an informational website, and a biennial workshop featuring hands-on training from members of the Indiana O'Brien Center and imaging experts from around the world.

Entities:  

Keywords:  O'Brien Center; fluorescence microscopy; intravital microscopy; kidney

Mesh:

Year:  2021        PMID: 33682441      PMCID: PMC8174807          DOI: 10.1152/ajprenal.00007.2021

Source DB:  PubMed          Journal:  Am J Physiol Renal Physiol        ISSN: 1522-1466


  78 in total

1.  Voxx: a PC-based, near real-time volume rendering system for biological microscopy.

Authors:  Jeffrey L Clendenon; Carrie L Phillips; Ruben M Sandoval; Shiaofen Fang; Kenneth W Dunn
Journal:  Am J Physiol Cell Physiol       Date:  2002-01       Impact factor: 4.249

Review 2.  Intravital imaging of the kidney using multiparameter multiphoton microscopy.

Authors:  Kenneth W Dunn; Ruben M Sandoval; Bruce A Molitoris
Journal:  Nephron Exp Nephrol       Date:  2003

3.  Intravital imaging of the kidney in a rat model of salt-sensitive hypertension.

Authors:  Bradley T Endres; Ruben M Sandoval; George J Rhodes; Silvia B Campos-Bilderback; Malgorzata M Kamocka; Christopher McDermott-Roe; Alexander Staruschenko; Bruce A Molitoris; Aron M Geurts; Oleg Palygin
Journal:  Am J Physiol Renal Physiol       Date:  2017-04-12

Review 4.  Procedures and applications of long-term intravital microscopy.

Authors:  Chloé Prunier; Na Chen; Laila Ritsma; Nienke Vrisekoop
Journal:  Methods       Date:  2017-06-30       Impact factor: 3.608

5.  A novel method to determine specificity and sensitivity of the TUNEL reaction in the quantitation of apoptosis.

Authors:  K J Kelly; Ruben M Sandoval; Kenneth W Dunn; Bruce A Molitoris; Pierre C Dagher
Journal:  Am J Physiol Cell Physiol       Date:  2002-12-21       Impact factor: 4.249

6.  Impaired tubular uptake explains albuminuria in early diabetic nephropathy.

Authors:  Leileata M Russo; Ruben M Sandoval; Silvia B Campos; Bruce A Molitoris; Wayne D Comper; Dennis Brown
Journal:  J Am Soc Nephrol       Date:  2008-12-31       Impact factor: 10.121

7.  Renal cysts of inv/inv mice resemble early infantile nephronophthisis.

Authors:  Carrie L Phillips; Karen J Miller; Adele J Filson; Jens Nürnberger; Jeffrey L Clendenon; Gregory W Cook; Kenneth W Dunn; Paul A Overbeek; Vincent H Gattone; Robert L Bacallao
Journal:  J Am Soc Nephrol       Date:  2004-07       Impact factor: 10.121

8.  A Precision Medicine Approach Uncovers a Unique Signature of Neutrophils in Patients With Brushite Kidney Stones.

Authors:  Mohammad Shahidul Makki; Seth Winfree; James E Lingeman; Frank A Witzmann; Elaine M Worcester; Amy E Krambeck; Fredric L Coe; Andrew P Evan; Sharon Bledsoe; Kristin J Bergsland; Suraj Khochare; Daria Barwinska; James C Williams; Tarek M El-Achkar
Journal:  Kidney Int Rep       Date:  2020-02-20

9.  A computational model of liver tissue damage and repair.

Authors:  Priyom Adhyapok; Xiao Fu; James P Sluka; Sherry G Clendenon; Victoria D Sluka; Zemin Wang; Kenneth Dunn; James E Klaunig; James A Glazier
Journal:  PLoS One       Date:  2020-12-21       Impact factor: 3.240

10.  Multiplex immunohistochemistry accurately defines the immune context of metastatic melanoma.

Authors:  H Halse; A J Colebatch; P Petrone; M A Henderson; J K Mills; H Snow; J A Westwood; S Sandhu; J M Raleigh; A Behren; J Cebon; P K Darcy; M H Kershaw; G A McArthur; D E Gyorki; P J Neeson
Journal:  Sci Rep       Date:  2018-07-24       Impact factor: 4.379

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  5 in total

Review 1.  The Michigan O'Brien Kidney Research Center: transforming translational kidney research through systems biology.

Authors:  Markus Bitzer; Wenjun Ju; Lalita Subramanian; Jonathan P Troost; Joseph Tychewicz; Becky Steck; Roger C Wiggins; Debbie S Gipson; Crystal A Gadegbeku; Frank C Brosius; Matthias Kretzler; Subramaniam Pennathur
Journal:  Am J Physiol Renal Physiol       Date:  2022-08-04

Review 2.  Tissue Cytometry With Machine Learning in Kidney: From Small Specimens to Big Data.

Authors:  Tarek M El-Achkar; Seth Winfree; Niloy Talukder; Daria Barwinska; Michael J Ferkowicz; Mohammad Al Hasan
Journal:  Front Physiol       Date:  2022-03-04       Impact factor: 4.755

Review 3.  Digital Image Analysis Tools Developed by the Indiana O'Brien Center.

Authors:  Kenneth W Dunn
Journal:  Front Physiol       Date:  2021-12-16       Impact factor: 4.566

Review 4.  Intravital Multiphoton Microscopy as a Tool for Studying Renal Physiology, Pathophysiology and Therapeutics.

Authors:  Bruce A Molitoris; Ruben M Sandoval; Mark C Wagner
Journal:  Front Physiol       Date:  2022-03-24       Impact factor: 4.755

Review 5.  Albumin uptake and processing by the proximal tubule: physiological, pathological, and therapeutic implications.

Authors:  Bruce A Molitoris; Ruben M Sandoval; Shiv Pratap S Yadav; Mark C Wagner
Journal:  Physiol Rev       Date:  2022-04-04       Impact factor: 46.500

  5 in total

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