Literature DB >> 33681841

Arthroscopic bursectomy less effective in the degenerative shoulder with chronic subacromial pain.

Hamez Gacaferi1,2, Arjen Kolk2, Cornelis P J Visser1.   

Abstract

BACKGROUND: Varying results after surgery in patients with subacromial pain syndrome (SAPS) have raised the question on whether there is a subgroup of patients that can benefit from surgery. Therefore, we aimed to identify preoperative and peroperative factors associated with a favorable patient-reported outcome after arthroscopic bursectomy in patients with SAPS.
METHODS: Patients with chronic SAPS who underwent arthroscopic bursectomy after failed conservative management were included (n = 94). Patients were evaluated at the baseline, and 2 weeks, 8 weeks, 6 months, and 1 year after surgery. The primary outcome was the Western Ontario Rotator Cuff index (WORC) score one year after surgery. The secondary outcome measure was a visual analog scale for pain. Mixed model analyses were used to identify prognostic factors.
RESULTS: The mean WORC (mean difference 39%, 95% confidence interval (CI) 32.8-45.3, P < .001) and visual analog scale pain scores (mean difference 41 mm points, 95% CI 3.37-4.88, P < .001) significantly improved one year after surgery. Nineteen patients (20%) developed a postoperative frozen shoulder. A longer duration of preoperative complaints and the peroperative identification of degenerative glenoid cartilage were associated with significantly worse WORC scores, with -0.086% per month (95% CI -0.156 to -0.016, P = .016) and -20% (95% CI -39.4 to -1.26, P = .037), respectively.
CONCLUSION: We identified demographic and clinical factors that predict the course after arthroscopic subacromial bursectomy. We found that arthroscopic bursectomy is less effective in patients with SAPS with a degenerative shoulder. This finding suggests that an improved treatment effect of arthroscopic subacromial bursectomy can be expected in patients with chronic SAPS if intra-articular pathologies such as glenohumeral osteoarthritis are sufficiently excluded.
© 2020 The Authors.

Entities:  

Keywords:  SAIS; SAPS; Shoulder; arthroscopy; rotator cuff; subacromial impingement syndrome; subacromial pain syndrome

Year:  2020        PMID: 33681841      PMCID: PMC7910744          DOI: 10.1016/j.jseint.2020.10.021

Source DB:  PubMed          Journal:  JSES Int        ISSN: 2666-6383


Shoulder pain is a global disease burden and it covers 10–18% of all visits at the general practitioner.,,, Most complaints are attributed to subacromial pain syndrome (SAPS), more commonly known as subacromial impingement syndrome, which affects patients between the ages of 30 and 60 years. A variety of entities, including bursitis, supraspinatus tendinopathy, partial tear of the rotator cuff (RC), biceps tendinitis, and degeneration of the acromioclavicular (AC) joint have all been described in literature as part of SAPS.,, Patients with SAPS encounter severe impairment on daily life activities, including work., Although most patients are treated with conservative strategies, some patients remain symptomatic and therefore receive surgical treatment (subacromial decompression surgery).,, At the beginning of this decade, there was an increase in arthroscopic subacromial decompression, making it one of the most frequently performed interventions in orthopedics., Yet, studies report inconsistent results with a substantial group of patients still experiencing pain or impaired shoulder function after surgery.,, Moreover, randomized studies failed to prove a clinically important difference favoring surgical bursectomy with or without subacromial decompression over conservative management with physiotherapy.,, Controversial results urged the orthopedic shoulder community to search for factors characterizing patients who are more likely to benefit from surgery.,, We therefore aimed to evaluate if there are factors that can predict the course after arthroscopic subacromial bursectomy in patients with SAPS. To answer this question, we conducted a prospective cohort study to identify preoperative and peroperative prognostic factors associated with a favorable patient-reported outcome in patients with SAPS after arthroscopic bursectomy. Peroperative factors can then possibly be identified preoperatively with other methods in future patients. Bursectomies (without acromioplasty) might be considered effective by those who support the idea of an intrinsic cause of SAPS, as it removes the inflamed bursa, while considering the changes of the acromion to be secondary., Second, resection of adhesions might improve subacromial motion and might provide a better clearance of subacromial tissues, with an increase in subacromial space., Because a number of patients develop a frozen shoulder after shoulder surgery (ranging from 5 to 34% in literature), our secondary aim was to identify predictive factors for the development of postoperative frozen shoulder.,,

Materials and methods

Study design and participants

In this prospective cohort study, we recruited all patients with chronic SAPS who underwent an arthroscopic bursectomy at a secondary referral center (Alrijne Hospital, Leiderdorp) between May 2013 and February 2015. Patients were eligible for inclusion in case of chronic SAPS, which was defined as nontraumatic shoulder pain for at least 6 months, that was localized around the humeral head and the lateral upper arm, which increased during elevation of the arm. Physical examination revealed a positive sign for all of the following tests: Jobe test, Hawkins-Kennedy test and painful supraspinatus and infraspinatus resistance tests (without muscle weakness)., Furthermore, all patients had conservative therapies before they were eligible for surgery, that is, a positive reaction to at least one subacromial corticosteroid infiltration and multiple sessions of physiotherapy. Finally, conventional radiographs of the shoulder and ultrasounds were made to assess the RC and exclude other pathologies like radiographic glenohumeral osteoarthritis. An additional magnetic resonance imaging of the shoulder was made if the physical examination and ultrasound were inconclusive. All diagnoses were made by a senior orthopedic surgeon specialized in arthroscopic shoulder surgery (CV). As per literature, the SAPS entity includes patients with bursitis, supraspinatus tendinopathy, partial tear of the RC, biceps tendinitis, with or without degeneration of the AC joint., Patients with both SAPS symptoms and osteoarthritis of the AC joint were considered eligible and underwent an additional distal clavicle resection. Osteoarthritis of the AC joint was confirmed through a positive AC compression test, signs of osteoarthritis on conventional radiographs, and positive marcainization test. Exclusion criteria were a full-thickness RC tear (either on preoperative radiographic/ultrasound imaging or during surgery), preoperative restriction in passive shoulder motion (frozen shoulder), history of frozen shoulder at the affected side, glenohumeral osteoarthritis, concomitant tenodesis/tenotomy, labral deficits during surgery (such as SLAP/Bankart lesions), interfering complaints deriving from a degenerative cervical spine, and patients under the age of 30 years. The Medical Ethical Committee of the Leiden University Medical Centre approved the study protocol (protocol number P15.348). Written informed consent was obtained from all participants. A total of 111 patients with SAPS were screened to participate in this study. Subsequently, 16 patients were excluded before surgery for the following reasons: 7 patients had a full-thickness RC tear on preoperative radiologic/ultrasonic imaging, 3 had signs of cervical radiculopathy, and 6 patients had surgery cancelled for various reasons. During surgery a full-thickness RC tear was found in two patients, resulting in 93 participating subjects (Figure 1). One year after surgery, 20 patients were lost to follow-up, leaving 73 patients (78%) for analysis.
Figure 1

Flow diagram. n, number; RC, rotator cuff; MRI, magnetic resonance imaging; CVA, cerebrovascular accident.

Flow diagram. n, number; RC, rotator cuff; MRI, magnetic resonance imaging; CVA, cerebrovascular accident.

Intervention

All patients underwent surgery under general anesthesia. Patients were positioned in the lateral decubitus position with their arm in traction. Two portals were created in the shoulder. First, a dorsal portal was created to inspect the glenohumeral joint. A lateral portal was created lateral to the front edge of the acromion. In case of AC pathology, an additional anterior portal was made below and in line with the AC joint. Bursectomy was performed through the lateral portal with a radiofrequency ablator (VAPR®, DePuy Synthes). Fibrotic and thickened soft tissue attached to the undersurface of the acromion was removed routinely. In case of osteoarthritis of the AC joint, a distal clavicle resection was done with a bur (Linvatec). Finally, the wounds were closed with wound closure strips and skin glue. In addition, 20 mL of levobupivacaine 0,5% was injected in the bursal space. The senior orthopedic surgeon specialized in arthroscopic shoulder surgery (CV) performed all of the surgical interventions. All patients underwent subacromial bursectomy for signs of SAPS: subacromial inflammation (n = 88) with or without bursal RC lesions (n = 44). Concomitant findings were osteoarthritis of the AC joint (n = 53), a hooked acromion (n = 15) and biceps tendinopathy (n = 7) for which a distal clavicle resection, subacromial decompression or biceps tenotomy were performed. Postoperatively patients were discharged from the hospital with a rehabilitation sling for two weeks and were allowed to use their arm for activities of daily living. Furthermore, patients were allowed to start with physiotherapy after the outpatient check-up 2 weeks after surgery. Physiotherapy started with performing gently guided active exercises to prevent stiffness due to inactivity. On the other hand, patients were advised to minimize exercises to avoid pain because pain can lead to immobility and stiffness, which in turn might evoke capsulitis (postoperative frozen shoulder). After 6 weeks, physiotherapy was targeted at shoulder proprioception and shoulder muscle strength to improve shoulder movements.

Evaluation of potential prognostic factors

Preoperative demographic determinants at the baseline were age (years), duration of preoperative complaints (months), sex (male/female), history of trauma (yes/no), involved side (left/right), hand dominance (left/right), involved in sports (yes/no), workers compensation (yes/no), diabetes mellitus (yes/no), hypothyroidism (yes/no), cardiovascular disease (yes/no), Dupuytren’s contracture (yes/no), and the American Society of Anesthesiologists (ASA) score (ASA 1, 2, or 3).,,,,, Furthermore, anteroposterior oblique internal rotation view (Grashey view) and outlet view radiographs of the shoulder joint were evaluated. The radiographic assessment consisted of measuring the acromion-humerus distance, the radius of the humeral head, the glenoid length, the acromial slope angle and the critical shoulder angle (CSA),,,,, (Appendix 1). Baseline characteristics can be found in Table I.
Table I

Baseline characteristics

Baseline characteristicsn = 93
Age, mean (SD), y55 (9.5)
Duration preoperative complaints, median (range), m23 (6-480)
Sex (female), n (%)58 (62)
Result of traumatic event, n (%)18 (19)
Right side involved, n (%)53 (57)
Right hand dominance, n (%)64 (69)
Active in sports, n (%)47 (51)
Workers compensation, n (%)12 (13)
Comorbidity:
 Diabetes mellitus, n (%)10 (11)
 Hypothyroidism, n (%)5 (5.4)
 Cardiovascular disease, n (%)13 (14)
 Dupuytren’s contracture, n (%)7 (7.5)
 ASA score:
 1, n (%)62 (67)
 2, n (%)25 (27)
 3, n (%)6 (6.5)
Radiology characteristics
Acromion-humerus distance, mean (SD), cm11 (1.6)
Radius humerus head, mean (SD), cm26 (2.9)
Glenoid length, superior to inferior, mean (SD), cm39 (4.0)
Critical Shoulder Angle, mean (SD), degrees33 (4.4)
Acromial slope angle, mean (SD), degrees154 (10)

n, number; SD, standard deviation; y, years; m, months; ASA, American Society of Anesthesiologists classification.

Baseline characteristics n, number; SD, standard deviation; y, years; m, months; ASA, American Society of Anesthesiologists classification. Finally, we prospectively scored the following findings during the operation (Table II): degenerative glenoid (≥ Outerbridge grade II chondropathy; yes/no), degenerative humeral head cartilage (≥ Outerbridge grade II chondropathy; yes/no), labral lesion (yes/no), articular RC lesion (yes/no), inflammation in the axillary fold (yes/no), subacromial bursitis (normal/inflammatory/adhesive), thickness of the coracoacromial ligament ( yes/no; meaning thicker than the thickness of the radiofrequency ablator (>5 mm), acromial osteophytes (yes/no), osteoarthritis of the AC joint (yes/no), biceps tendinopathy (yes/no), and bursal RC lesion (yes/no), respectively.,,,,
Table II

Peroperative characteristics

Peroperative characteristicsn = 93
Degenerative glenoid cartilage, n (%)14 (15)
Degenerative humeral head cartilage, n (%)9 (9.7)
Labral lesion, n (%)2 (2.2)
Articular RC lesion, n (%)3 (3.2)
Inflamed axillary fold, n (%)27 (29)
Subacromial bursa:
 Normal bursa, n (%)5 (5.4)
 Inflammatory bursitis, n (%)25 (27)
 Adhesive bursitis, n (%)63 (68)
Thick CA ligament (>5 mm under acromion), n (%)24 (26)
Osteophytes acromion, n (%)11 (12)
Osteoarthritis of the AC joint, n (%)53 (57)
Biceps tendinopathy, n (%)7 (7.5)
Bursal RC lesion, n (%)44 (47)

n, number; RC, rotator cuff; CA, coracoacromial; mm, millimetre; AC, acromioclavicular.

Chondropathy ≥ grade 2.

Peroperative characteristics n, number; RC, rotator cuff; CA, coracoacromial; mm, millimetre; AC, acromioclavicular. Chondropathy ≥ grade 2.

Outcome measures

Patients were evaluated at the baseline and at standardized follow-up visits at 2 weeks, 8 weeks, and 6 months. One year after surgery, questionnaires were sent via regular mail, with an additional reminder via post, including a phone call, if the participants did not respond after 3 months. The primary outcome was the Western Ontario Rotator Cuff index (WORC) score and it was obtained at the baseline and during the standardized follow-up visits at 8 weeks, 6 months, and one year after surgery. Secondary outcomes were the visual analog scale (VAS) for pain (0 to 100 mm, 100 m indicated severe pain), which was obtained at the baseline and after one year. In addition, the development of a postoperative frozen shoulder was recorded at the standardized follow-up visits at 8 weeks and 6 months. A postoperative frozen shoulder was defined as described by Koorevaar et al (2017): an initially successful postoperative rehabilitation process after shoulder surgery is followed by worsening of (night) pain at the deltoid insertion with a painful restriction of active and passive movement, limited to <100° elevation, <30° external rotation and internal rotation limited to L5 or less. Finally, additional questions about patient satisfaction and rehabilitation (including number of physiotherapy visits) were evaluated after one year (Appendix 2).

Statistical analysis

Parametric continuous data were expressed as means and 95% confidence intervals (CIs) and nonparametric data were expressed as median and interquartile range. Categorical data were expressed as numbers and percentages. A paired Student t-test was used to compare the preoperative and one-year postoperative WORC and VAS scores. A linear mixed model analysis was used to determine prognostic factors for the change in WORC score. To model the within patient variance, a random intercept in combination with a heterogenous first-order autoregressive (ARH1) covariance structure was chosen. The dependent variable was the WORC score measured at the baseline, 8 weeks, 6 months, and 1 year. Follow-up time (baseline, 8 weeks, 6 months, and 1 year) was included as the repeated factor. The demographic, radiographic, and peroperative factors were modeled as fixed effects. Linear regression analysis was used to identify prognostic factors influencing pain experienced at 1 year after surgery, with the VAS score as the dependent factor. Finally, a logistic regression analysis was performed to study the factors that may predict the occurrence of a frozen shoulder. For each of the analyses, independent factors in univariable analysis with a correlation of P < .15 qualified for multivariable analysis (WORC), multiple linear regression (VAS), and multiple logistic regression models (frozen shoulder). A two-sided P value of <.05 was considered to be statistically significant. Statistical analyses were performed using IBM SPSS statistics (version 25.0, IBM Inc., Armonk, NY, USA).

Results

Demographics

The mean age of the included group was 55 years (SD 9.5) and most (n = 58, 62%) of included patients were women (Table I). The median duration of preoperative complaints was 23 months (range 6–480). One year after surgery, the mean WORC significantly improved from 40% at the baseline to 79% (mean difference 39%, 95% CI 32.8–45.3, P < .001) (Figure 2). The mean VAS score significantly improved from 58 mm at the baseline to 17 mm (mean difference 41 mm points, 95% CI 3.37–4.88, P < .001) at 1-year follow-up. Finally, 19 patients (20%) developed a postoperative frozen shoulder within one year after arthroscopic bursectomy.
Figure 2

WORC score after arthroscopic bursectomy. Error bars: 95% confidence interval. WORC, Western Ontario Rotator Cuff index.

WORC score after arthroscopic bursectomy. Error bars: 95% confidence interval. WORC, Western Ontario Rotator Cuff index. The vast majority of patients (80%) were happy with the surgery, and knowing the postoperative results 86% would choose surgery again (Appendix 3). Approximately 57% started working within 10 weeks after surgery. Most patients received between 20 and 30 physiotherapy treatments. Finally, 5 months after surgery 85% of the patients quit physiotherapy.

WORC score

The following factors qualified for our multivariable linear mixed model analysis: duration of preoperative complaints, radius of the humeral head, glenoid length, (female) sex, diabetes mellitus, and workers compensation (Appendix 4). Mixed model analysis showed that having workers compensation was predictive for a worse baseline WORC score (Table III). A longer duration of preoperative complaints and the peroperative identification of degenerative glenoid cartilage had a negative impact on the improvement of the WORC score, with −0.086% per month (95% CI −0.156 to −0.016, P = .016) and −20% (95% CI −39.4 to −1.26, P = .037), respectively.
Table III

Mixed model analysis WORC

Mixed models analysis WORC
FactorsEstimate95% CI
P value
Lower boundUpper bound
Baseline
 Age, y−0.12−0.6700.424.656
 Duration of symptoms, m−0.030−0.07860.0194.232
 Radius humerus head, cm0.71−2.323.75.641
 Glenoid length, cm0.18−1.631.98.846
 Sex (female)−0.53−19.017.9.954
 Workers compensation−12−25.41.90.0900
 Diabetes mellitus5.8−9.0920.7.439
 Biceps pathology9.9−7.8627.6.270
 Degenerative glenoid cartilage3.1−11.417.6.670
Follow-up
 Age, y−0.0024−0.7570.752.995
 Duration of symptoms, m−0.086−0.156−0.0164.0160
 Radius humerus head, cm1.2−3.155.46.596
 Glenoid length, cm−0.11−2.772.56.938
 Sex (female)15−11.140.4.263
 Workers compensation−5.1−24.414.3.606
 Diabetes mellitus−7.4−27.812.9.470
 Biceps pathology−20−43.74.13.104
 Degenerative glenoid cartilage−20−39.4−1.26.0370

CI, confidence interval; y, years; m, months; cm, centimetre; WORC, Western Ontario Rotator Cuff index.

Bold values indicate P < .05.

Mixed model analysis: follow-up time (baseline, 8 weeks, 6 months, and 1 year), age, duration of preoperative complaints, radius humeral head, glenoid length, sex, workers compensation, diabetes mellitus, biceps tendinopathy, age × follow-up time, duration of preoperative complaints × follow-up time, radius humeral head × follow-up time, glenoid length × follow-up time, sex × follow-up time, workers compensation × follow-up time, diabetes mellitus x follow-up time, and biceps tendinopathy x follow-up time were investigated as fixed effects.

Mixed model analysis WORC CI, confidence interval; y, years; m, months; cm, centimetre; WORC, Western Ontario Rotator Cuff index. Bold values indicate P < .05. Mixed model analysis: follow-up time (baseline, 8 weeks, 6 months, and 1 year), age, duration of preoperative complaints, radius humeral head, glenoid length, sex, workers compensation, diabetes mellitus, biceps tendinopathy, age × follow-up time, duration of preoperative complaints × follow-up time, radius humeral head × follow-up time, glenoid length × follow-up time, sex × follow-up time, workers compensation × follow-up time, diabetes mellitus x follow-up time, and biceps tendinopathy x follow-up time were investigated as fixed effects.

Pain (VAS)

Duration of preoperative complaints, involved side, hand dominance, degenerative glenoid cartilage, degenerative humeral head cartilage, and labral lesion qualified for our multivariable linear regression analysis (Appendix 5). A longer duration of preoperative complaints was an independent predictor for an unfavorable course of pain, indicated by 1 mm (95% CI 0.005 to 0.018, P = .001) higher VAS for pain per month of complaints (Table IV).
Table IV

Multiple linear regression analysis VAS

FactorsMean95% CI
P value
Lower boundUpper bound
Constant−2.0−5.181.13.203
Duration of preoperative complaints0.0120.005000.0180.001
Involved side (left)0.64−0.7051.99.341
Hand dominance (left)0.91−0.7302.54.270
Degenerative glenoid cartilage−1.1−3.701.59.426
Degenerative humeral cartilage−2.0−4.940.849.161
Labral lesion−0.70−3.962.55.666

CI, confidence interval; VAS, visual analog scale.

Bold values indicate P < .05.

Multiple linear regression analysis VAS CI, confidence interval; VAS, visual analog scale. Bold values indicate P < .05.

Frozen shoulder

Sex, workers compensation, and CSA met our predefined criteria in the univariable logistic regression (Appendix 6). Multiple logistic regression analysis showed that a greater CSA had lower odds for the development of a postoperative frozen shoulder, with an odds ratio of 0.86 (95% CI 0.743 to 0.993, P = .04) (Table V). On the other hand, having workers compensation was an independent risk factor for the development of a postoperative frozen shoulder with an odds ratio of 4.4 (95% CI 1.07 to 18.0, P = .04).
Table V

Multiple logistic regression analysis: predictors for frozen shoulder

FactorsOR95% CI for OR
P value
Lower boundUpper bound
Sex (female)2.50.7169.04.149
Critical shoulder angle0.860.7430.993.0400
Workers compensation4.41.0718.0.0400
Constant67--.103

OR, odds ratio; CI, confidence interval.

Bold values indicate P < .05.

Multiple logistic regression analysis: predictors for frozen shoulder OR, odds ratio; CI, confidence interval. Bold values indicate P < .05.

Discussion

We conducted a prospective cohort study to identify preoperative and peroperative prognostic factors associated with favorable patient-reported outcomes after arthroscopic bursectomy in patients with chronic SAPS. One year after surgery, the mean WORC and VAS for pain scores improved significantly. About 19 patients (20%) developed a postoperative frozen shoulder. A longer duration of preoperative complaints and the peroperative identification of degenerative glenoid cartilage resulted in significantly worse results. A longer duration of preoperative complaints was also an independent predictor for an unfavorable course of pain. Finally, we found that a greater CSA was associated with lower odds for the development of a postoperative frozen shoulder, whereas having workers compensation was an independent risk factor. In line with literature, we found that longer duration of preoperative complaints was associated with an unfavorable course of SAPS after surgical bursectomy.,,, Interestingly, the peroperative identification of glenoid degeneration was also identified as a negative predictor for patient-reported outcomes after arthroscopic subacromial bursectomy. These results indicate that arthroscopic bursectomy on the nondegenerative shoulder joint results in better patient-reported outcomes compared with the degenerative shoulder. Our findings are in line with literature on knee arthroscopy, which shows unfavorable results for arthroscopy in degenerative knees with a degenerative meniscus tear. This led to an adjustment of the guidelines, advising against arthroscopic meniscectomy for degenerative meniscus tears. Recent literature on SAPS also showed no beneficial effect of bursectomy or arthroscopic decompression over (placebo) arthroscopy only, leading to guidelines advocating conservative treatment for SAPS.,,, Although shoulder function and pain improved in most of our patients following this procedure, and there was a high satisfaction rate (80%), we acknowledge that this still might be due to a surgical placebo effect as shown by randomized studies.,, Rather than continuing arthroscopy in all patients, we have to identify and select the correct patient that benefits from surgery. Like in knee arthroscopy, our results indicate that arthroscopic subacromial bursectomy provides better outcomes in shoulders without degeneration. A logical explanation would be that the patients suspected to suffer from subacromial pain, are in fact having complaints due to glenohumeral chondropathy. Nineteen patients (20%) developed a postoperative frozen shoulder in this study which is in line with numbers in literature (5%–32%).,,, Our prospective design and strict diagnostic criteria contributed to a close observation of shoulder motion, and thus a more precise estimation of the prevalence of postoperative frozen shoulders, making information bias less likely. Remarkably, most frozen shoulders developed 6 weeks after surgery with initially a good start. We argue whether this might be due to (over)use in combination with the regenerating subacromial bursa after surgery. Furthermore, our findings suggested that workers compensation might be predictive for developing a postoperative frozen shoulder. In most upper extremity surgery (and orthopedic surgery in general), patients receiving workers compensation have worse prognosis after surgery than patients without workers compensation., The exact reason for this effect is unknown, but it has been argued that these worse results may be due to psychological effects caused by injustice and victimisation. We did find that a greater CSA on the preoperative shoulder radiograph was a protective factor for the development of a postoperative frozen shoulder. Although the CSA has been associated with several shoulder pathologies, it has not been associated with frozen shoulder., Factors such as hypothyroidism and diabetes mellitus have been associated with both idiopathic as well as postoperative frozen shoulders.,, We did not find an association between a postoperative frozen shoulder and these previous identified risk factors for a frozen shoulder. This could be due to a low prevalence of these risk factors in our study leading to an underpowered analysis to detect an effect. Our findings should urge surgeons to reconsider arthroscopic bursectomy in SAPS patients with intra-articular pathology (such as degenerative joint cartilage). Given that the intra-articular pathology was identified during surgery, rather than during preoperative assessment or imaging, it might be worthwhile to assess the degree of degeneration before surgery with different methods (such as magnetic resonance imaging scan). Although conservative treatment should be pursued in most patients with SAPS, it could be considered in patients who were unsuccessfully treated with conservative options. New prognostic studies may further help identify subgroups within this SAPS group that will benefit from arthroscopic bursectomy after failed conservative management. Future research should include bigger cohorts for the investigated prognostic factors to avoid underpowered studies. Once identified, these subgroups could then be investigated in randomized placebo-controlled surgical trials (such as the CSAW and FIMPACT studies) to address the effectiveness of surgical procedures in these specific subgroups., This study has several limitations. First, inherent to all cohort studies, we are only able to adjust for known associations and thus leaving room for confounding. We therefore tried to include various potential prognostic factors which have been previously described in literature to minimize confounding. Second, the loss of follow-up might have contributed to attrition bias. Despite our efforts, our loss to follow-up is substantial (22%). However, our follow-up rate is considered acceptable (78%), and for this reason, we believe that the loss of follow-up has not severely altered our conclusions. Furthermore, besides arthroscopic bursectomy, some patients received additional surgical procedures, clouding associations between arthroscopic bursectomy and patient-reported outcome. Finally, the number of patients with hypothyroidism, Dupuytren’s contracture, and cardiovascular disease was low, resulting in a limited power.

Conclusion

This study identified both demographic and clinical factors that predict the course after arthroscopic subacromial bursectomy. After failed conservative treatment, most patients had an improvement in WORC and VAS pain scores after arthroscopic bursectomy. A greater CSA was associated with lower odds for the development of a postoperative frozen shoulder, whereas having workers compensation was an independent risk factor. We found that arthroscopic bursectomy is less effective in patients with SAPS with a degenerative shoulder. This finding suggests that an improved treatment effect of arthroscopic subacromial bursectomy can be expected in patients with chronic SAPS if intra-articular pathologies such as glenohumeral osteoarthritis are sufficiently excluded.

Disclaimer

The authors, their immediate families, and any research foundations with which they are affiliated have not received any financial payments or other benefits from any commercial entity related to the subject of this article. No funding was disclosed by the author(s).
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