BACKGROUND: Hashimoto's thyroiditis can be present with a localized palpable nodule though presentation as a hyperfunction "nodule" is extremely rare. The first case of Hashimoto's thyroiditis and hot nodule was reported in 1971 by Warner. CASE PRESENTATION: We reported a 26-year-old hypothyroid woman in Hashimoto's thyroiditis background with a hyperactive thyroid nodule in both 99mTc and I131scintigraphy. The nodule disappeared after eight months of sufficient thyroid hormone replacement therapy. CONCLUSION: Toxic adenoma in hypothyroid patients can be resolved after levothyroxine (L-T4) replacement therapy.
BACKGROUND: Hashimoto's thyroiditis can be present with a localized palpable nodule though presentation as a hyperfunction "nodule" is extremely rare. The first case of Hashimoto's thyroiditis and hot nodule was reported in 1971 by Warner. CASE PRESENTATION: We reported a 26-year-old hypothyroid woman in Hashimoto's thyroiditis background with a hyperactive thyroid nodule in both 99mTc and I131scintigraphy. The nodule disappeared after eight months of sufficient thyroid hormone replacement therapy. CONCLUSION: Toxic adenoma in hypothyroid patients can be resolved after levothyroxine (L-T4) replacement therapy.
Authors: F Bogazzi; L Bartalena; S Brogioni; A Burelli; L Manetti; M L Tanda; M Gasperi; E Martino Journal: Eur J Endocrinol Date: 1999-05 Impact factor: 6.664