Literature DB >> 33679992

Situation of Rabies in Ethiopia: A Five-Year Retrospective Study of Human Rabies in Addis Ababa and the Surrounding Regions.

Mesfin Aklilu1, Wogayehu Tadele1, Amelework Alemu1, Sintayehu Abdela1, Garuma Getahun1, Alemnesh Hailemariam1, Yirgalem Tadesse1, Gutu Kitila1, Endalkachew Birhanu1, Ibsa Fli1, Abebe Getachew1, Yimer Mulugeta1.   

Abstract

OBJECTIVE: The study objective was to estimate the burden of human rabies in Ethiopia from 2015-2019. Study Design. A descriptive study design was applied to measure the size of the problem.
METHOD: Retrospective data were used from the Ethiopian Public Health Institute rabies case record book that was registered between 2015 to 2019. RESULT: Eighty-seven (87) cases of human rabies were diagnosed clinically in the Ethiopian Public Health Institute over the period of five years (2015-2019) with 100% case fatality. Of these, 83 (95.4%) cases were attributed to dog bites, whereas 1 (1.1%) to a cat and 3 (3.4%) to wild animals. The fatalities were from Oromia (n = 51 (58.6%), 13 (14.9%) were from Amhara, 15 (17.2%) were from Addis Ababa, and 8 (9.2%) from the Southern region. All referred cases had no record of immunization against rabies except eight. Ineffective postexposure treatment was the reason for 5 (5.7%) deaths. Out of 1,652 brain samples of different animals, mainly dogs, submitted for examination, 1,122 (68%) were found to be positive for rabies by the FAT. Dog bites were more common among males than females. The number of dog bite victims who had visited the EPHI counseling office and recommended to take postexposure prophylaxis against rabies both from Addis Ababa and the surrounding areas were 9,592 and 4,192, respectively. Out of these, 5,708 were males and 3,884 females for the capital Addis Ababa. Similarly, 2,439 males and 1,753 females account for areas surrounding Addis Ababa. Among those exposed from Addis Ababa, 1,079 (11.2%) were in the age group less than five, 1696 (17.7%) were in the age group 6-13, and 6,817 (71.1%) in the age group 14 and greater. Victims from outside of the capital Addis Ababa account for 644 (15.4%) for the age group less than 5 years, 964 (23%) for the age group 6-13 and, 2,584 (61.6%) for the age group 14 and greater.
CONCLUSION: Mechanisms must be sought to reduce the cost of PEP and means of obtaining funds so as to initiate timely treatment for rabies exposed individuals of low socioeconomic status. Besides prevention, strategies should focus on public education and strict dog population control.
Copyright © 2021 Mesfin Aklilu et al.

Entities:  

Year:  2021        PMID: 33679992      PMCID: PMC7910060          DOI: 10.1155/2021/6662073

Source DB:  PubMed          Journal:  J Trop Med        ISSN: 1687-9686


  10 in total

1.  Rabies deaths in Pakistan: results of ineffective post-exposure treatment.

Authors:  Shehzad Parviz; Rashid Chotani; Joseph McCormick; Sue Fisher-Hoch; Stephen Luby
Journal:  Int J Infect Dis       Date:  2004-11       Impact factor: 3.623

2.  Cost-effectiveness modelling studies of all preventive measures against rabies: A systematic review.

Authors:  Thunyarat Anothaisintawee; Anne Julienne Genuino; Montarat Thavorncharoensap; Sitaporn Youngkong; Waranya Rattanavipapong; Aronrag Meeyai; Usa Chaikledkaew
Journal:  Vaccine       Date:  2018-12-13       Impact factor: 3.641

Review 3.  Rabies molecular virology, diagnosis, prevention and treatment.

Authors:  Muhammad Zubair Yousaf; Muhammad Qasim; Sadia Zia; Muti ur Rehman Khan; Usman Ali Ashfaq; Sanaullah Khan
Journal:  Virol J       Date:  2012-02-21       Impact factor: 4.099

4.  Estimating the burden of rabies in Ethiopia by tracing dog bite victims.

Authors:  Tariku Jibat Beyene; Monique C M Mourits; Abraham Haile Kidane; Henk Hogeveen
Journal:  PLoS One       Date:  2018-02-21       Impact factor: 3.240

5.  Level and pattern of human rabies and dog bites in Techiman Municipality in the Middle Belt of Ghana: a six year retrospective records review.

Authors:  Damien Tioyire Punguyire; Anthony Osei-Tutu; Emmanuel Vikpenibe Aleser; Timothy Letsa
Journal:  Pan Afr Med J       Date:  2017-11-30

6.  Incidence of rabies in humans and domestic animals and people's awareness in North Gondar Zone, Ethiopia.

Authors:  Wudu Temesgen Jemberu; Wassie Molla; Gizat Almaw; Sefinew Alemu
Journal:  PLoS Negl Trop Dis       Date:  2013-05-09

7.  Rabies exposures, post-exposure prophylaxis and deaths in a region of endemic canine rabies.

Authors:  Katie Hampson; Andy Dobson; Magai Kaare; Jonathan Dushoff; Matthias Magoto; Emmanuel Sindoya; Sarah Cleaveland
Journal:  PLoS Negl Trop Dis       Date:  2008-11-25

Review 8.  Advances in rabies prophylaxis and treatment with emphasis on immunoresponse mechanisms.

Authors:  A El-Sayed
Journal:  Int J Vet Sci Med       Date:  2018-05-18

9.  The WHO position on rabies immunization - 2018 updates.

Authors:  Katherine L O'Brien; Terry Nolan
Journal:  Vaccine       Date:  2018-10-17       Impact factor: 3.641

10.  The need to improve access to rabies post-exposure vaccines: Lessons from Tanzania.

Authors:  Joel Changalucha; Rachel Steenson; Eleanor Grieve; Sarah Cleaveland; Tiziana Lembo; Kennedy Lushasi; Geofrey Mchau; Zacharia Mtema; Maganga Sambo; Alphoncina Nanai; Nicodem J Govella; Angel Dilip; Lwitiko Sikana; Francesco Ventura; Katie Hampson
Journal:  Vaccine       Date:  2018-10-08       Impact factor: 3.641

  10 in total
  1 in total

1.  Rabies prevention and control practices and associated factors among dog owners in Chiro, West Hararghe, Ethiopia.

Authors:  Mohammed Jemal Ahmed; Gebisa Dirirsa; Dechasa Adare Mengistu; Melake Demena; Abraham Geremew
Journal:  J Public Health Res       Date:  2022-10-13
  1 in total

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