Literature DB >> 33679604

Healthy Gut, Healthy Bones: Targeting the Gut Microbiome to Promote Bone Health.

Olivia D Cooney1,2, Prabhakar R Nagareddy3, Andrew J Murphy1,2,4, Man K S Lee1,2,4.   

Abstract

Over the past decade, the use of probiotics to modify the gut microbiome has become a public spotlight in reducing the severity of a number of chronic diseases such as autoimmune disease, diabetes, cancer and cardiovascular disease. Recently, the gut microbiome has been shown to play an important role in regulating bone mass. Therefore, targeting the gut microbiome may be a potential alternative avenue for those with osteopenia or osteoporosis. In this mini-review, we take the opportunity to delve into how the different components of the gut work together and how the gut-related diseases impact on bone health.
Copyright © 2021 Cooney, Nagareddy, Murphy and Lee.

Entities:  

Keywords:  Th17 & Tregs cells; bone; gut; microbiome; short chain fatty acid

Mesh:

Year:  2021        PMID: 33679604      PMCID: PMC7933548          DOI: 10.3389/fendo.2020.620466

Source DB:  PubMed          Journal:  Front Endocrinol (Lausanne)        ISSN: 1664-2392            Impact factor:   5.555


  64 in total

1.  Lactobacillus acidophilus alleviates type 2 diabetes by regulating hepatic glucose, lipid metabolism and gut microbiota in mice.

Authors:  Fenfen Yan; Na Li; Jialu Shi; Huizhen Li; Yingxue Yue; Wenshu Jiao; Nana Wang; Yue Song; Guicheng Huo; Bailiang Li
Journal:  Food Funct       Date:  2019-08-28       Impact factor: 5.396

2.  Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors.

Authors:  T Kikuchi; T Matsuguchi; N Tsuboi; A Mitani; S Tanaka; M Matsuoka; G Yamamoto; T Hishikawa; T Noguchi; Y Yoshikai
Journal:  J Immunol       Date:  2001-03-01       Impact factor: 5.422

3.  CpG oligodeoxynucleotides modulate the osteoclastogenic activity of osteoblasts via Toll-like receptor 9.

Authors:  Wei Zou; Alla Amcheslavsky; Zvi Bar-Shavit
Journal:  J Biol Chem       Date:  2003-02-28       Impact factor: 5.157

4.  Lactobacillus plantarum ZDY04 exhibits a strain-specific property of lowering TMAO via the modulation of gut microbiota in mice.

Authors:  Liang Qiu; Xueying Tao; Hua Xiong; Jun Yu; Hua Wei
Journal:  Food Funct       Date:  2018-08-15       Impact factor: 5.396

5.  Antibiotics in early life alter the murine colonic microbiome and adiposity.

Authors:  Ilseung Cho; Shingo Yamanishi; Laura Cox; Barbara A Methé; Jiri Zavadil; Kelvin Li; Zhan Gao; Douglas Mahana; Kartik Raju; Isabel Teitler; Huilin Li; Alexander V Alekseyenko; Martin J Blaser
Journal:  Nature       Date:  2012-08-30       Impact factor: 49.962

6.  Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction.

Authors:  Kojiro Sato; Ayako Suematsu; Kazuo Okamoto; Akira Yamaguchi; Yasuyuki Morishita; Yuho Kadono; Sakae Tanaka; Tatsuhiko Kodama; Shizuo Akira; Yoichiro Iwakura; Daniel J Cua; Hiroshi Takayanagi
Journal:  J Exp Med       Date:  2006-11-06       Impact factor: 14.307

7.  PTH induces bone loss via microbial-dependent expansion of intestinal TNF+ T cells and Th17 cells.

Authors:  Mingcan Yu; Abdul Malik Tyagi; Jau-Yi Li; Jonathan Adams; Timothy L Denning; M Neale Weitzmann; Rheinallt M Jones; Roberto Pacifici
Journal:  Nat Commun       Date:  2020-01-24       Impact factor: 14.919

Review 8.  Biology of Bone Tissue: Structure, Function, and Factors That Influence Bone Cells.

Authors:  Rinaldo Florencio-Silva; Gisela Rodrigues da Silva Sasso; Estela Sasso-Cerri; Manuel Jesus Simões; Paulo Sérgio Cerri
Journal:  Biomed Res Int       Date:  2015-07-13       Impact factor: 3.411

9.  Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR-S6K pathway.

Authors:  J Park; M Kim; S G Kang; A H Jannasch; B Cooper; J Patterson; C H Kim
Journal:  Mucosal Immunol       Date:  2014-06-11       Impact factor: 7.313

10.  Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis.

Authors:  Narges Tajik; Michael Frech; Oscar Schulz; Fabian Schälter; Sébastien Lucas; Vugar Azizov; Kerstin Dürholz; Franziska Steffen; Yasunori Omata; Andreas Rings; Marko Bertog; Aroldo Rizzo; Aida Iljazovic; Marijana Basic; Arnd Kleyer; Stephan Culemann; Gerhard Krönke; Yubin Luo; Klaus Überla; Udo S Gaipl; Benjamin Frey; Till Strowig; Kerstin Sarter; Stephan C Bischoff; Stefan Wirtz; Juan D Cañete; Francesco Ciccia; Georg Schett; Mario M Zaiss
Journal:  Nat Commun       Date:  2020-04-24       Impact factor: 14.919

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  9 in total

Review 1.  New Advances in Improving Bone Health Based on Specific Gut Microbiota.

Authors:  Qihui Yan; Liping Cai; Weiying Guo
Journal:  Front Cell Infect Microbiol       Date:  2022-07-04       Impact factor: 6.073

2.  Probiotics Enhance Bone Growth and Rescue BMP Inhibition: New Transgenic Zebrafish Lines to Study Bone Health.

Authors:  Jerry Maria Sojan; Ratish Raman; Marc Muller; Oliana Carnevali; Jörg Renn
Journal:  Int J Mol Sci       Date:  2022-04-26       Impact factor: 6.208

Review 3.  Understanding the Complexities and Changes of the Astronaut Microbiome for Successful Long-Duration Space Missions.

Authors:  Donatella Tesei; Anna Jewczynko; Anne M Lynch; Camilla Urbaniak
Journal:  Life (Basel)       Date:  2022-03-28

4.  Maternal Gut Microbiome Decelerates Fetal Endochondral Bone Formation by Inducing Inflammatory Reaction.

Authors:  Yoko Uchida-Fukuhara; Takako Hattori; Shanqi Fu; Sei Kondo; Miho Kuwahara; Daiki Fukuhara; Md Monirul Islam; Kota Kataoka; Daisuke Ekuni; Satoshi Kubota; Manabu Morita; Mika Iikegame; Hirohiko Okamura
Journal:  Microorganisms       Date:  2022-05-10

5.  Regulation of Inflammatory Response by Transmembrane Adaptor Protein LST1.

Authors:  Matej Fabisik; Jolana Tureckova; Nataliia Pavliuchenko; Jarmila Kralova; Jana Balounova; Kristina Vicikova; Tereza Skopcova; Frantisek Spoutil; Jana Pokorna; Pavla Angelisova; Bernard Malissen; Jan Prochazka; Radislav Sedlacek; Tomas Brdicka
Journal:  Front Immunol       Date:  2021-04-27       Impact factor: 7.561

Review 6.  The gut microbiota can be a potential regulator and treatment target of bone metastasis.

Authors:  Kelly F Contino; Hariom Yadav; Yusuke Shiozawa
Journal:  Biochem Pharmacol       Date:  2022-01-15       Impact factor: 5.858

7.  Gut Microbiome Signature Are Correlated With Bone Mineral Density Alterations in the Chinese Elders.

Authors:  Yangyang Wang; Xiaoguang Gao; Jing Lv; Yuhong Zeng; Qingmei Li; Liping Wang; Yuanyuan Zhang; Wenjie Gao; Jihan Wang
Journal:  Front Cell Infect Microbiol       Date:  2022-03-31       Impact factor: 5.293

8.  Effect of Administration of Azithromycin and/or Probiotic Bacteria on Bones of Estrogen-Deficient Rats.

Authors:  Urszula Cegieła; Piotr Londzin; Aleksandra Janas; Maria Pytlik; Joanna Folwarczna
Journal:  Pharmaceuticals (Basel)       Date:  2022-07-24

Review 9.  A patient with Turner syndrome received the percutaneous vertebroplasty seven times: a case report and literature review.

Authors:  Longyu Li; Yifang Shi; Nan Zhao; Zhengpei Liu; Zhe Zhao; Zongmian Song; Sailei Zheng; Miaoheng Yan; Zikuan Leng; Songfeng Chen; Guowei Shang; Hongwei Kou; Hongjian Liu
Journal:  Eur J Med Res       Date:  2021-12-07       Impact factor: 2.175

  9 in total

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