INTRODUCTION: Venous thromboembolism (VTE) is a known complication after total knee arthroplasty (TKA) with well-established morbidity, mortality, and significant healthcare expenditure. However, no standard form of prophylaxis against VTE currently exists. METHODS: A retrospective review was performed identifying 12,866 TKA cases and post-operative VTE events using either 325 mg aspirin or 81 mg aspirin twice daily (BID). RESULTS: 133 VTE cases were diagnosed of the 9413 TKA on 325 mg aspirin BID compared to 8 VTE cases out of 3453 TKA on 81 mg aspirin BID (1.41% vs. 0.23%, p < 0.001). CONCLUSION: 81 mg aspirin BID significantly improved post-operative VTE rates over 325 mg aspirin BID.
INTRODUCTION: Venous thromboembolism (VTE) is a known complication after total knee arthroplasty (TKA) with well-established morbidity, mortality, and significant healthcare expenditure. However, no standard form of prophylaxis against VTE currently exists. METHODS: A retrospective review was performed identifying 12,866 TKA cases and post-operative VTE events using either 325 mg aspirin or 81 mg aspirin twice daily (BID). RESULTS: 133 VTE cases were diagnosed of the 9413 TKA on 325 mg aspirin BID compared to 8 VTE cases out of 3453 TKA on 81 mg aspirin BID (1.41% vs. 0.23%, p < 0.001). CONCLUSION: 81 mg aspirin BID significantly improved post-operative VTE rates over 325 mg aspirin BID.
Authors: Mhamad Faour; Nicolas S Piuzzi; David P Brigati; Alison K Klika; Michael A Mont; Wael K Barsoum; Carlos A Higuera Journal: J Arthroplasty Date: 2018-03-08 Impact factor: 4.757
Authors: Norman A Johanson; Paul F Lachiewicz; Jay R Lieberman; Paul A Lotke; Javad Parvizi; Vincent Pellegrini; Theodore A Stringer; Paul Tornetta; Robert H Haralson; William C Watters Journal: J Bone Joint Surg Am Date: 2009-07 Impact factor: 5.284
Authors: Javad Parvizi; Ronald Huang; Camilo Restrepo; Antonia F Chen; Matthew S Austin; William J Hozack; Jess H Lonner Journal: J Bone Joint Surg Am Date: 2017-01-18 Impact factor: 5.284
Authors: Khalid Odeh; James Doran; Stephen Yu; Nicholas Bolz; Joseph Bosco; Richard Iorio Journal: J Arthroplasty Date: 2016-03-16 Impact factor: 4.757