Literature DB >> 3367819

Resolution of neurotoxicity with anticholinesterase therapy in death-adder envenomation.

B Currie1, M Fitzmaurice, J Oakley.   

Abstract

A case of the reversal of death-adder (Acanthophis antarcticus) neurotoxicity by treatment with neostigmine methylsulphate in a Papua New Guinean villager is described. While antivenom remains the mainstay in the treatment of snake-bite envenomation, the possible role of anticholinesterase therapy for death-adder bites in Papua New Guinea is discussed. In addition, some problems with first-aid management are outlined.

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Year:  1988        PMID： 3367819     DOI： 10.5694/j.1326-5377.1988.tb99464.x

Source DB:  PubMed          Journal:  Med J Aust        ISSN： 0025-729X            Impact factor:   7.738


  6 in total

Review 1.  Snake bite in South Asia: a review.

Authors:  Emilie Alirol; Sanjib Kumar Sharma; Himmatrao Saluba Bawaskar; Ulrich Kuch; François Chappuis
Journal:  PLoS Negl Trop Dis       Date:  2010-01-26

2.  Death adder envenoming causes neurotoxicity not reversed by antivenom--Australian Snakebite Project (ASP-16).

Authors:  Christopher I Johnston; Margaret A O'Leary; Simon G A Brown; Bart J Currie; Lambros Halkidis; Richard Whitaker; Benjamin Close; Geoffrey K Isbister
Journal:  PLoS Negl Trop Dis       Date:  2012-09-27

3.  Reversal of experimental paralysis in a human by intranasal neostigmine aerosol suggests a novel approach to the early treatment of neurotoxic envenomation.

Authors:  Matthew R Lewin; Philip Bickler; Tom Heier; John Feiner; Lance Montauk; Brett Mensh
Journal:  Clin Case Rep       Date:  2013-07-24

Review 4.  Developing Small Molecule Therapeutics for the Initial and Adjunctive Treatment of Snakebite.

Authors:  Tommaso C Bulfone; Stephen P Samuel; Philip E Bickler; Matthew R Lewin
Journal:  J Trop Med       Date:  2018-07-30

Review 5.  Neurotoxicity in snakebite--the limits of our knowledge.

Authors:  Udaya K Ranawaka; David G Lalloo; H Janaka de Silva
Journal:  PLoS Negl Trop Dis       Date:  2013-10-10

6.  Varespladib (LY315920) Appears to Be a Potent, Broad-Spectrum, Inhibitor of Snake Venom Phospholipase A2 and a Possible Pre-Referral Treatment for Envenomation.

Authors:  Matthew Lewin; Stephen Samuel; Janie Merkel; Philip Bickler
Journal:  Toxins (Basel)       Date:  2016-08-25       Impact factor: 4.546
  6 in total

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