Literature DB >> 33677608

Effects of iron injection timing on suckling and subsequent nursery and growing-finishing performance and hematological criteria.

Hayden E Williams1, Brittany Carrender2, Cierra D Roubicek1, Ryan Maurer1, Joel M DeRouchey1, Jason C Woodworth1, Steve S Dritz3, Michael D Tokach1, Kyle F Coble2, Robert D Goodband1, Jordan T Gebhardt3.   

Abstract

Two experiments were conducted to evaluate the effects of Fe injection timing after birth on suckling and subsequent nursery and growing-finishing pig performance. The injectable Fe source used in both experiments was GleptoForte (Ceva Animal Health, LLC., Lenexa, KS). GleptoForte contains gleptoferron which is a Fe macromolecule complex. In Exp. 1, a total of 324 newborn pigs (DNA 241 × 600, initially 1.6 ± 0.04 kg body weight [BW]) within 27 litters were used. Two days after birth, all piglets were weighed, and six barrows and six gilts per litter were allotted to 1 of 6 treatments consisting of no Fe injection or 200 mg of injectable Fe provided in a single injection on d 2, 4, 6, 8, or 10 of age. Pigs were weaned (~21 d of age) and allotted to nursery pens with all pigs in each pen having received the same Fe treatment. In Exp. 2, a total of 1,892 newborn pigs (PIC 359 × C40; initially 1.5 ± 0.02 kg BW) within 172 litters were used. One day after birth, piglets were weighed, and 11 pigs within each litter were allotted to 1 of 6 treatments consisting of no Fe injection or 200 mg of injectable Fe provided on d 1, 3, 5, or 7 of age, or 200 mg on d 1 plus 200 mg on d 12 of age. Pigs were weaned (19 d of age) and placed in a commercial wean-to-finish facility in a total of 15 pens with equal representation of treatments in each pen. In both experiments, not providing an Fe injection after birth decreased (P < 0.05) preweaning average daily gain (ADG), weaning weight, and hemoglobin and hematocrit values compared with all other treatments. In Exp. 1, increasing the age that piglets received an Fe injection until 4 or 6 d after birth provided marginal evidence for an improvement (quadratic; P = 0.070) in preweaning ADG. For the nursery period, increasing the age that piglets received an Fe injection improved (quadratic; P = 0.013) d 80 BW, but there was no evidence of a difference (P > 0.10) in d 173 BW at the end of the grow-finish period. In Exp. 2, increasing the age that piglets received a 200 mg Fe injection showed no evidence of difference (P > 0.10) for subsequent nursery and growing-finishing ADG. In both experiments, hemoglobin and hematocrit values were decreased (linear; P < 0.05) at weaning with increasing age when pigs received an Fe injection. These experiments suggest that providing a 200 mg Fe injection within 7 d after farrowing is sufficient for optimizing preweaning and subsequent growth performance.
© The Author(s) 2021. Published by Oxford University Press on behalf of the American Society of Animal Science. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  Fe; gleptoferron; growth performance; timing

Mesh:

Substances:

Year:  2021        PMID: 33677608      PMCID: PMC8034417          DOI: 10.1093/jas/skab071

Source DB:  PubMed          Journal:  J Anim Sci        ISSN: 0021-8812            Impact factor:   3.159


  15 in total

1.  An evaluation of iron-dextran supplementation in piglets administered by injection on the first, third or fourth day after birth.

Authors:  A K Egeli; T Framstad
Journal:  Res Vet Sci       Date:  1999-06       Impact factor: 2.534

2.  Effects of increasing Fe dosage in newborn pigs on suckling and subsequent nursery performance and hematological and immunological criteria.

Authors:  Hayden E Williams; Joel M DeRouchey; Jason C Woodworth; Steven S Dritz; Michael D Tokach; Robert D Goodband; Andrew J Holtcamp; Eduarda M Bortoluzzi; Jordan T Gebhardt
Journal:  J Anim Sci       Date:  2020-08-01       Impact factor: 3.159

Review 3.  Chemistry and biology of eukaryotic iron metabolism.

Authors:  P Aisen; C Enns; M Wessling-Resnick
Journal:  Int J Biochem Cell Biol       Date:  2001-10       Impact factor: 5.085

Review 4.  Mechanisms of mammalian iron homeostasis.

Authors:  Kostas Pantopoulos; Suheel Kumar Porwal; Alan Tartakoff; L Devireddy
Journal:  Biochemistry       Date:  2012-07-09       Impact factor: 3.162

5.  Effect of vitamin E and selenium on iron utilization in neonatal pigs.

Authors:  G M Hill; J E Link; L Meyer; K L Fritsche
Journal:  J Anim Sci       Date:  1999-07       Impact factor: 3.159

Review 6.  Diagnosis and management of iron-deficiency anaemia.

Authors:  James D Cook
Journal:  Best Pract Res Clin Haematol       Date:  2005-06       Impact factor: 3.020

7.  Hematology and biochemistry reference intervals for Ontario commercial nursing pigs close to the time of weaning.

Authors:  Amanda M Perri; Terri L O'Sullivan; John C S Harding; R Darren Wood; Robert M Friendship
Journal:  Can Vet J       Date:  2017-04       Impact factor: 1.008

8.  Effects of iron supplementation on binding activity of iron regulatory proteins and the subsequent effect on growth performance and indices of hematological and mineral status of young pigs.

Authors:  M J Rincker; S L Clarke; R S Eisenstein; J E Link; G M Hill
Journal:  J Anim Sci       Date:  2005-09       Impact factor: 3.159

9.  Comparison of gleptoferron with iron dextran for anemia prevention in young pigs.

Authors:  D S Pollmann; J E Smith; J S Stevenson; D A Schoneweis; R H Hines
Journal:  J Anim Sci       Date:  1983-03       Impact factor: 3.159

10.  An update on modeling dose-response relationships: Accounting for correlated data structure and heterogeneous error variance in linear and nonlinear mixed models.

Authors:  M A D Gonçalves; N M Bello; S S Dritz; M D Tokach; J M DeRouchey; J C Woodworth; R D Goodband
Journal:  J Anim Sci       Date:  2016-05       Impact factor: 3.159

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.