Anao Zhang1, Kaipeng Wang2, Bradley Zebrack3, Chiu Yi Tan4, Emily Walling5, Rashmi Chugh6. 1. University of Michigan School of Social Work, United States. Electronic address: zhangan@umich.edu. 2. University of Denver Graduate School of Social Work, United States. 3. University of Michigan School of Social Work, United States. 4. University of Michigan Medical School Department of Psychiatry, United States. 5. University of Michigan Medical School Department of Pediatrics, United States. 6. University of Michigan Medical School Department of Internal Medicine, United States.
Abstract
BACKGROUND: Pediatric, adolescent, and young adult (PAYA) cancer survivors suffer from multiple domains of adverse psychosocial and behavioral outcomes during and after their cancer treatment. This study conducted a systematic review and metaanalysis of psychosocial, behavioral, and supportive interventions for PAYA cancer survivors. METHODS: We searched 11 electronic databases, 4 professional websites, and manual search of reference lists in existing reviews. We selected randomized controlled trials and controlled trials without randomization focusing on PAYA cancer survivors across six outcome domains. RESULTS: We included 61 studies (4,402 participants) published between 1987 and 2020. Overall risk of bias across studies was low. We identified an overall moderate and statistically significant treatment effect size for PAYA cancer survivors across six outcome domains. CONCLUSION: psychosocial, behavioral, and supportive interventions were overall effective for PAYA cancer survivors. However, interventions were not effective for certain outcome domains, and less effective among AYA versus pediatric cancer survivors.
BACKGROUND: Pediatric, adolescent, and young adult (PAYA) cancer survivors suffer from multiple domains of adverse psychosocial and behavioral outcomes during and after their cancer treatment. This study conducted a systematic review and metaanalysis of psychosocial, behavioral, and supportive interventions for PAYA cancer survivors. METHODS: We searched 11 electronic databases, 4 professional websites, and manual search of reference lists in existing reviews. We selected randomized controlled trials and controlled trials without randomization focusing on PAYA cancer survivors across six outcome domains. RESULTS: We included 61 studies (4,402 participants) published between 1987 and 2020. Overall risk of bias across studies was low. We identified an overall moderate and statistically significant treatment effect size for PAYA cancer survivors across six outcome domains. CONCLUSION: psychosocial, behavioral, and supportive interventions were overall effective for PAYA cancer survivors. However, interventions were not effective for certain outcome domains, and less effective among AYA versus pediatric cancer survivors.
Authors: Anao Zhang; Kaipeng Wang; Kate Blumenstein; Anna Brose; Chris Kemp; Dalton Meister; Phyllis Solomon Journal: Support Care Cancer Date: 2022-08-30 Impact factor: 3.359
Authors: Adrienne S Viola; Gary Kwok; Kristine Levonyan-Radloff; Sharon L Manne; Robert B Noll; Sean Phipps; Olle Jane Z Sahler; Katie A Devine Journal: Cancers (Basel) Date: 2022-06-25 Impact factor: 6.575
Authors: Anao Zhang; Aarti Kamat; Chiara Acquati; Michael Aratow; Johnny S Kim; Adam S DuVall; Emily Walling Journal: Cancers (Basel) Date: 2022-02-12 Impact factor: 6.639