Literature DB >> 33675655

Emergence of a Severe Acute Respiratory Syndrome Coronavirus 2 virus variant with novel genomic architecture in Hong Kong.

Herman Tse1, David Christopher Lung1,2, Sally Cheuk-Ying Wong1, Ka-Fai Ip1, Tak-Chiu Wu3, Kelvin Kai-Wang To4,5, Kin-Hang Kok4,5, Kwok-Yung Yuen4,5, Garnet Kwan-Yue Choi1.   

Abstract

Throughout the COVID-19 pandemic, divergent SARS-CoV-2 lineages have emerged continuously, mostly through the genomic accumulation of substitutions. We report the discovery of a SARS-CoV-2 variant with a novel genomic architecture characterized by absent ORF7a, ORF7b and ORF8, and a C-terminally modified ORF6 product resulting from partial 5'-UTR duplication and transposition.
© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  COVID-19; SARS-CoV-2; genomic rearrangement; whole-genome sequencing

Year:  2021        PMID： 33675655      PMCID： PMC7989571          DOI： 10.1093/cid/ciab198

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  5 in total

1.  The surveillance of spike protein for patients with COVID-19 detected in Hong Kong in 2020.

Authors:  Gannon C K Mak; Angela W L Lau; Andy M Y Chan; Edman T K Lam; Rickjason C W Chan; Dominic N C Tsang
Journal:  J Med Virol       Date:  2021-05-24       Impact factor: 20.693

Review 2.  SARS-CoV-2 Portrayed against HIV: Contrary Viral Strategies in Similar Disguise.

Authors:  Ralf Duerr; Keaton M Crosse; Ana M Valero-Jimenez; Meike Dittmann
Journal:  Microorganisms       Date:  2021-06-27

3.  High attack rate in a Tong Lau house outbreak of COVID-19 with subdivided units in Hong Kong.

Authors:  Qun Wang; David Christopher Lung; Pak-To Chan; Wei Jia; Chung-Hin Dung; Te Miao; Jianxiang Huang; Wenzhao Chen; Zixuan Wang; Kai-Ming Leung; Pengcheng Xu; Zhang Lin; Daniel Wong; Herman Tse; Sally Cheuk Ying Wong; Garnet Kwan-Yue Choi; Kelvin Kai-Wang To; Vincent Chi-Chung Cheng; Kwok-Yung Yuen; Yuguo Li
Journal:  Interface Focus       Date:  2022-02-11       Impact factor: 3.906

4.  Consecutive deletions in a unique Uruguayan SARS-CoV-2 lineage evidence the genetic variability potential of accessory genes.

Authors:  Yanina Panzera; Lucía Calleros; Natalia Goñi; Ana Marandino; Claudia Techera; Sofía Grecco; Natalia Ramos; Sandra Frabasile; Gonzalo Tomás; Emma Condon; María Noel Cortinas; Viviana Ramas; Leticia Coppola; Cecilia Sorhouet; Cristina Mogdasy; Héctor Chiparelli; Juan Arbiza; Adriana Delfraro; Ruben Pérez
Journal:  PLoS One       Date:  2022-02-17       Impact factor: 3.240

5.  An issue of concern: unique truncated ORF8 protein variants of SARS-CoV-2.

Authors:  Sk Sarif Hassan; Vaishnavi Kodakandla; Elrashdy M Redwan; Kenneth Lundstrom; Pabitra Pal Choudhury; Tarek Mohamed Abd El-Aziz; Kazuo Takayama; Ramesh Kandimalla; Amos Lal; Ángel Serrano-Aroca; Gajendra Kumar Azad; Alaa A A Aljabali; Giorgio Palù; Gaurav Chauhan; Parise Adadi; Murtaza Tambuwala; Adam M Brufsky; Wagner Baetas-da-Cruz; Debmalya Barh; Vasco Azevedo; Nikolas G Bazan; Bruno Silva Andrade; Raner José Santana Silva; Vladimir N Uversky
Journal:  PeerJ       Date:  2022-03-21       Impact factor: 2.984
  5 in total

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