Nuria Viudes-Sarrion1,2, Enrique Velasco2, Miguel Delicado-Miralles2, Carmen Lillo-Navarro3,4,5. 1. Área de Fisioterapia. Departamento de Patología y Cirugía, Universidad Miguel Hernández, 03550, San Juan de Alicante, Spain. 2. Instituto de Neurociencias de Alicante (CSIC-Universidad Miguel Hernández), San Juan de Alicante, Spain. 3. Área de Fisioterapia. Departamento de Patología y Cirugía, Universidad Miguel Hernández, 03550, San Juan de Alicante, Spain. mclillo@umh.es. 4. Instituto de Neurociencias de Alicante (CSIC-Universidad Miguel Hernández), San Juan de Alicante, Spain. mclillo@umh.es. 5. CEIT Fisioterapia. UMH, San Juan de Alicante, Spain. mclillo@umh.es.
Abstract
OBJECTIVE: To systematically review the literature on the use of the transcranial static magnetic stimulation (tSMS) technique in humans and animals, its effects on different areas of the central nervous system (CNS), its influence on neural excitability and on the subject's behavior, and its biological effects and future possibilities. All static magnetic field applications that can be considered to have a physiologically similar effect have been reviewed. METHODS: We searched studies using key terms in NCBI PubMed, Scopus, PEDro, SciELO, Cochrane, and links to publications (inception to September 2019). Three reviewers independently selected the studies, extracted data, and assessed the methodological quality of the studies using the recommendations described in the Cochrane Handbook for Systematic Reviews of Interventions, PRISMA guidelines. RESULTS: We analyzed 27 studies. The reviewed literature suggests that the use of these magnetic fields has an inhibitory effect on different areas of the CNS, such as motor, somatosensory, and visual cortex, cerebellum, and spinal cord. Regarding subject's behavior, the different effects of tSMS appear to be transient and dependent on the stimulated area, such as loss of visual discrimination or improvement of somatosensory perception. In addition, the technique has some therapeutic utility, specifically in pathologies with cortical hyperexcitability. CONCLUSIONS: These results suggest that tSMS may be a promising tool to modulate cerebral excitability in a safe and non-invasive way. Further investigations could give a better explanation of its precise mechanisms of action and applications.
OBJECTIVE: To systematically review the literature on the use of the transcranial static magnetic stimulation (tSMS) technique in humans and animals, its effects on different areas of the central nervous system (CNS), its influence on neural excitability and on the subject's behavior, and its biological effects and future possibilities. All static magnetic field applications that can be considered to have a physiologically similar effect have been reviewed. METHODS: We searched studies using key terms in NCBI PubMed, Scopus, PEDro, SciELO, Cochrane, and links to publications (inception to September 2019). Three reviewers independently selected the studies, extracted data, and assessed the methodological quality of the studies using the recommendations described in the Cochrane Handbook for Systematic Reviews of Interventions, PRISMA guidelines. RESULTS: We analyzed 27 studies. The reviewed literature suggests that the use of these magnetic fields has an inhibitory effect on different areas of the CNS, such as motor, somatosensory, and visual cortex, cerebellum, and spinal cord. Regarding subject's behavior, the different effects of tSMS appear to be transient and dependent on the stimulated area, such as loss of visual discrimination or improvement of somatosensory perception. In addition, the technique has some therapeutic utility, specifically in pathologies with cortical hyperexcitability. CONCLUSIONS: These results suggest that tSMS may be a promising tool to modulate cerebral excitability in a safe and non-invasive way. Further investigations could give a better explanation of its precise mechanisms of action and applications.
Entities:
Keywords:
Brain stimulation; Central nervous system; Magnetic field; Neurophysiology; Systematic review
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