Literature DB >> 33673847

Take home injectable opioids for opioid use disorder during and after the COVID-19 Pandemic is in urgent need: a case study.

Eugenia Oviedo-Joekes1,2, Scott MacDonald3, Charles Boissonneault4, Kelli Harper3.   

Abstract

BACKGROUND: In North America the opioid poisoning crisis currently faces the unprecedented challenges brought by the COVID-19 pandemic, further straining people and communities already facing structural and individual vulnerabilities. People with opioid use disorder (OUD) are facing unique challenges in response to COVID-19, such as not being able to adopt best practices (e.g., physical distancing) if they're financially insecure or living in shelters (or homeless). They also have other medical conditions that make them more likely to be immunocompromised and at risk of developing COVID-19. In response to the COVID-19 public health emergency, national and provincial regulatory bodies introduced guidance and exemptions to mitigate the spread of the virus. Among them, clinical guidance for prescribers were issued to allow take home opioid medications for opioid agonist treatment (OAT). Take Home for injectable opioid agonist treatment (iOAT) is only considered within a restrictive regulatory structure, specific to the pandemic. Nevertheless, this risk mitigation guidance allowed carries, mostly daily dispensed, to a population that would not have access to it prior to the pandemic. In this case it is presented and discussed that if a carry was possible during the pandemic, then the carry could continue post COVID-19 to address a gap in our approach to individualize care for people with OUD receiving iOAT. CASE
PRESENTATION: Here we present the first case of a patient in Canada with long-term OUD that received take home injectable diacetylmorphine to self-isolate in an approved site after being diagnosed with COVID-19 during a visit to the emergency room where he was diagnosed with cellulitis and admitted to receive antibiotics.
CONCLUSION: In the present case we demonstrated that it is feasible to provide iOAT outside the community clinic with no apparent negative consequences. Improving upon and making permanent these recently introduced risk mitigating guidance during COVID-19, have the potential not just to protect during the pandemic, but also to address long-overdue barriers to access evidence-based care in addiction treatment.

Entities:  

Keywords:  Diacetylmorphine; Direct observed treatment; Injectable opioid agonist treatment; Opioid use disorder; Patient centered care; Take home doses

Mesh:

Substances:

Year:  2021        PMID: 33673847      PMCID: PMC7935000          DOI: 10.1186/s13011-021-00358-x

Source DB:  PubMed          Journal:  Subst Abuse Treat Prev Policy        ISSN: 1747-597X


  21 in total

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Authors:  Marica Ferri; Marina Davoli; Carlo A Perucci
Journal:  Cochrane Database Syst Rev       Date:  2011-12-07

Review 2.  The Impact of Misuse and Diversion of Opioid Substitution Treatment Medicines: Evidence Review and Expert Consensus.

Authors:  Jens Reimer; Nat Wright; Lorenzo Somaini; Carlos Roncero; Icro Maremmani; Neil McKeganey; Richard Littlewood; Peter Krajci; Hannu Alho; Oscar D'Agnone
Journal:  Eur Addict Res       Date:  2015-10-02       Impact factor: 3.015

Review 3.  Addressing misuse and diversion of opioid substitution medication: guidance based on systematic evidence review and real-world experience.

Authors:  Nat Wright; Oscar D'Agnone; Peter Krajci; Richard Littlewood; Hannu Alho; Jens Reimer; Carlos Roncero; Lorenzo Somaini; Icro Maremmani
Journal:  J Public Health (Oxf)       Date:  2015-10-27       Impact factor: 2.341

4.  Expanding access to diacetylmorphine and hydromorphone for people who use opioids in Canada.

Authors:  Nazlee Maghsoudi; Jeanette Bowles; Dan Werb
Journal:  Can J Public Health       Date:  2020-03-27

5.  Increasing diversion of methadone in Vancouver, Canada, 2005-2015.

Authors:  Hudson Reddon; Joel Ho; Kora DeBeck; M-J Milloy; Yang Liu; Huiru Dong; Keith Ahamad; Evan Wood; Thomas Kerr; Kanna Hayashi
Journal:  J Subst Abuse Treat       Date:  2017-11-28

6.  Safety profile of injectable hydromorphone and diacetylmorphine for long-term severe opioid use disorder.

Authors:  Eugenia Oviedo-Joekes; Suzanne Brissette; Scott MacDonald; Daphne Guh; Kirsten Marchand; Salima Jutha; Scott Harrison; Amin Janmohamed; Derek Z Zhang; Aslam H Anis; Michael Krausz; David C Marsh; Martin T Schechter
Journal:  Drug Alcohol Depend       Date:  2017-05-10       Impact factor: 4.492

Review 7.  From morphine clinics to buprenorphine: regulating opioid agonist treatment of addiction in the United States.

Authors:  Jerome H Jaffe; Charles O'Keeffe
Journal:  Drug Alcohol Depend       Date:  2003-05-21       Impact factor: 4.492

8.  Correlates of Patient-Centered Care Practices at U.S. Substance Use Disorder Clinics.

Authors:  Sunggeun Ethan Park; Colleen M Grogan; Jennifer E Mosley; Keith Humphreys; Harold A Pollack; Peter D Friedmann
Journal:  Psychiatr Serv       Date:  2019-09-10       Impact factor: 3.084

9.  Hydromorphone Compared With Diacetylmorphine for Long-term Opioid Dependence: A Randomized Clinical Trial.

Authors:  Eugenia Oviedo-Joekes; Daphne Guh; Suzanne Brissette; Kirsten Marchand; Scott MacDonald; Kurt Lock; Scott Harrison; Amin Janmohamed; Aslam H Anis; Michael Krausz; David C Marsh; Martin T Schechter
Journal:  JAMA Psychiatry       Date:  2016-05-01       Impact factor: 21.596

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  6 in total

1.  Nasal administration of diacetylmorphine improved the adherence in a patient receiving heroin-assisted treatment.

Authors:  Maximilian Meyer; Jean N Westenberg; Johannes Strasser; Kenneth M Dürsteler; Undine E Lang; Michael Krausz; Marc Vogel
Journal:  Harm Reduct J       Date:  2022-06-07

Review 2.  Strategies Adopted by Addiction Facilities during the Coronavirus Pandemic to Support Treatment for Individuals in Recovery or Struggling with a Substance Use Disorder: A Scoping Review.

Authors:  Divane de Vargas; Caroline Figueira Pereira; Rosa Jacinto Volpato; Ana Vitória Corrêa Lima; Rogério da Silva Ferreira; Sheila Ramos de Oliveira; Thiago Faustino Aguilar
Journal:  Int J Environ Res Public Health       Date:  2021-11-18       Impact factor: 4.614

3.  Experiences with take-home dosing in heroin-assisted treatment in Switzerland during the COVID-19 pandemic-Is an update of legal restrictions warranted?

Authors:  Maximilian Meyer; Johannes Strasser; Patrick Köck; Marc Walter; Marc Vogel; Kenneth M Dürsteler
Journal:  Int J Drug Policy       Date:  2021-11-26

4.  Case report: acute care management of severe opioid withdrawal with IV fentanyl.

Authors:  Pouya Azar; Jean N Westenberg; Martha J Ignaszewski; James S H Wong; George Isac; Nickie Mathew; R Michael Krausz
Journal:  Addict Sci Clin Pract       Date:  2022-04-05

5.  Treatment retention in opioid agonist therapy: comparison of methadone versus buprenorphine/naloxone by analysis of daily-witnessed dispensed medication in a Canadian Province.

Authors:  Joseph Sadek; Joseph Saunders
Journal:  BMC Psychiatry       Date:  2022-07-30       Impact factor: 4.144

6.  Moving towards a continuum of safer supply options for people who use drugs: A qualitative study exploring national perspectives on safer supply among professional stakeholders in Canada.

Authors:  Annie Foreman-Mackey; Bernie Pauly; Andrew Ivsins; Karen Urbanoski; Manal Mansoor; Geoff Bardwell
Journal:  Subst Abuse Treat Prev Policy       Date:  2022-10-08
  6 in total

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