| Literature DB >> 33673595 |
Mei-Ling Li1, Shin-Ru Shih2,3,4,5, Blanton S Tolbert6, Gary Brewer1.
Abstract
Enterovirus A71 (EV-A71) is a major causative agent of hand, foot, and mouth disease (HFMD) and herpangina. Moreover, EV-A71 infection can lead to neurological complications and death. Vaccination is the most efficient way to control virus infection. There are currently three inactivated, whole EV-A71 vaccines licensed by the China NMPA (National Medical Products Administration). Several other types of vaccines, such as virus-like particles and recombinant VP1 (capsid protein), are also under development. In this review, we discuss recent advances in the development of EV-A71 vaccines.Entities:
Keywords: Enterovirus A71; Sinovac; foot and mouth disease (HFMD); hand; vaccine
Year: 2021 PMID: 33673595 PMCID: PMC7997495 DOI: 10.3390/vaccines9030199
Source DB: PubMed Journal: Vaccines (Basel) ISSN: 2076-393X