Literature DB >> 33673573

Targeted Physical Therapy Combined with Spasticity Management Changes Motor Development Trajectory for a 2-Year-Old with Cerebral Palsy.

Corri L Stuyvenberg1, Shaaron E Brown2, Ketaki Inamdar3, Megan Evans4, Lin-Ya Hsu5, Olivier Rolin6, Regina T Harbourne7, Sarah Westcott McCoy5, Michele A Lobo8, Natalie A Koziol9, Stacey C Dusing10.   

Abstract

Therapies for children with cerebral palsy (CP) often fail to address essential components of early rehabilitation: intensity, child initiation, and an embodied approach. Sitting Together And Reaching To Play (START-Play) addresses these issues while incorporating intensive family involvement to maximize therapeutic dosage. While START-Play was developed and tested on children aged 7-16 months with motor delays, the theoretical construct can be applied to intervention in children of broader ages and skills levels. This study quantifies the impact of a broader START-Play intervention combined with Botulinum toxin-A (BoNT-A) and phenol on the developmental trajectory of a 24 month-old child with bilateral spastic CP. In this AB +1 study, A consisted of multiple baseline assessments with the Gross Motor Function Measure-66 and the Assessment of Problem Solving in Play. The research participant demonstrated a stable baseline during A and changes in response to the combination of BoNT-A/phenol and 12 START-Play sessions during B, surpassing the minimal clinically important difference on the Gross Motor Function Measure-66. The follow-up data point (+1) was completed after a second round of BoNT-A/phenol injections. While the findings suggest the participant improved his gross motor skills with BoNT-A/phenol and START-Play, further research is needed to generalize these findings.

Entities:  

Keywords:  Botulinum toxin-A; cerebral palsy; early intervention; phenol; physical therapy

Year:  2021        PMID: 33673573      PMCID: PMC7997196          DOI: 10.3390/jpm11030163

Source DB:  PubMed          Journal:  J Pers Med        ISSN: 2075-4426


  48 in total

1.  Short-term effects of "botulinum toxin a" as treatment for children with cerebral palsy: kinematic and kinetic aspects at the ankle joint.

Authors:  M Galli; M Crivellini; G C Santambrogio; E Fazzi; F Motta
Journal:  Funct Neurol       Date:  2001 Oct-Dec

2.  Efficacy of Supporting Play Exploration and Early Development Intervention in the First Months of Life for Infants Born Very Preterm: 3-Arm Randomized Clinical Trial Protocol.

Authors:  Stacey C Dusing; Jennifer C Burnsed; Shaaron E Brown; Amy D Harper; Karen D Hendricks-Munoz; Richard D Stevenson; Leroy R Thacker; Rebecca M Molinini
Journal:  Phys Ther       Date:  2020-08-12

Review 3.  Effect of early intervention in infants at very high risk of cerebral palsy: a systematic review.

Authors:  Mijna Hadders-Algra; Anke G Boxum; Tjitske Hielkema; Elisa G Hamer
Journal:  Dev Med Child Neurol       Date:  2016-12-07       Impact factor: 5.449

4.  Botulinum toxin type A neuromuscular blockade in the treatment of lower extremity spasticity in cerebral palsy: a randomized, double-blind, placebo-controlled trial. BOTOX Study Group.

Authors:  L A Koman; J F Mooney; B P Smith; F Walker; J M Leon
Journal:  J Pediatr Orthop       Date:  2000 Jan-Feb       Impact factor: 2.324

5.  Management of spasticity in cerebral palsied children by peripheral nerve block with phenol.

Authors:  R Spira
Journal:  Dev Med Child Neurol       Date:  1971-04       Impact factor: 5.449

6.  Science does not speak for itself: translating child development research for the public and its policymakers.

Authors:  Jack P Shonkoff; Susan Nall Bales
Journal:  Child Dev       Date:  2011 Jan-Feb

7.  Sitting Together And Reaching To Play (START-Play): Protocol for a Multisite Randomized Controlled Efficacy Trial on Intervention for Infants With Neuromotor Disorders.

Authors:  Regina T Harbourne; Stacey C Dusing; Michele A Lobo; Sarah Westcott-McCoy; James Bovaird; Susan Sheridan; James C Galloway; Hui-Ju Chang; Lin-Ya Hsu; Natalie Koziol; Emily C Marcinowski; Iryna Babik
Journal:  Phys Ther       Date:  2018-06-01

8.  Development as a dynamic system.

Authors:  Linda B. Smith; Esther Thelen
Journal:  Trends Cogn Sci       Date:  2003-08       Impact factor: 20.229

9.  Measuring Early Problem-Solving in Young Children with Motor Delays: A Validation Study.

Authors:  Rebecca M Molinini; Natalie A Koziol; Tanya Tripathi; Regina T Harbourne; Sarah Westcott McCoy; Michele A Lobo; James Bovaird; Stacey C Dusing
Journal:  Phys Occup Ther Pediatr       Date:  2021-02-01       Impact factor: 2.360

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  1 in total

1.  The SIT-PT Trial Protocol: A Dose-Matched Randomized Clinical Trial Comparing 2 Physical Therapist Interventions for Infants and Toddlers With Cerebral Palsy.

Authors:  Stacey C Dusing; Regina T Harbourne; Lin-Ya Hsu; Natalie A Koziol; Kari Kretch; Barbara Sargent; Sandra Jensen-Willett; Sarah Westcott McCoy; Douglas L Vanderbilt
Journal:  Phys Ther       Date:  2022-07-04
  1 in total

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