| Literature DB >> 33673314 |
Dmitry Gribanyov1, Gleb Zhdanov2, Andrei Olenin2, Georgii Lisichkin2, Alexandra Gambaryan3, Vladimir Kukushkin1, Elena Zavyalova2.
Abstract
Development of sensitive techniques for rapid detection of viruses is on a high demand. Surface-enhanced Raman spectroscopy (SERS) is an appropriate tool for new techniques due to its high sensitivity. DNA aptamers are short structured oligonucleotides that can provide specificity for SERS biosensors. Existing SERS-based aptasensors for rapid virus detection had several disadvantages. Some of them lacked possibility of quantitative determination, while others had sophisticated and expensive implementation. In this paper, we provide a new approach that combines rapid specific detection and the possibility of quantitative determination of viruses using the example of influenza A virus.Entities:
Keywords: SERS; aptamer; aptasensor; influenza; nanoparticles; virus detection
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Year: 2021 PMID: 33673314 PMCID: PMC7918581 DOI: 10.3390/ijms22041842
Source DB: PubMed Journal: Int J Mol Sci ISSN: 1422-0067 Impact factor: 5.923