Literature DB >> 33670124

Use of Phil Embolic Agent for Bleeding in Non-Neurological Interventions.

Pierleone Lucatelli1, Mario Corona1, Leonardo Teodoli1, Piergiorgio Nardis1, Alessandro Cannavale1, Bianca Rocco1, Claudio Trobiani1, Stefano Cipollari1, Simone Zilahi de Gyurgyokai1, Mario Bezzi1, Carlo Catalano1.   

Abstract

OBJECTIVE: To evaluate the safety and efficacy of the Phil liquid embolic agent in non-neurological embolization procedures. M&M: Thirty-five patients with a mean age of 62.5 years underwent percutaneous embolization using Phil for the treatment of visceral arterial bleedings in 20/35 patients (including three gluteal, one bladder, two superior mesenteric, three epigastric, one deep femoral, five internal iliac, four intercostal, and one lingual arteries), splanchnic pseudoaneurysms in 11/35 patients (including three hepatic, five splenic, and three renal arteries), pancreatic bleeding metastasis in 1/35 patient, and gastric bleeding varices in 3/35 patients. Phil is composed of a non-adhesive copolymer dissolved in DMSO (Anhydrous Dimethyl Sulfoxide) with different viscosity. Procedures were performed slowly under continuous fluoroscopic guidance to avoid embolization of non-target vessels.
RESULTS: Clinical success was obtained with a single intervention in 34 cases (97.15%), while a repeated procedure was required in one case (2.85%). No technical complications nor non-target embolization occurred. A case of post-embolic syndrome was noted (2.85%) in one patient. DMSO administration-related pain was successfully controlled by medical therapy.
CONCLUSION: Phil can be considered a safe and effective embolic agent for the treatment of non-neurologic bleeding.

Entities:  

Keywords:  bleeding; liquid embolic agent; non-neurologic intervention; transcatheter embolization

Year:  2021        PMID: 33670124     DOI: 10.3390/jcm10040701

Source DB:  PubMed          Journal:  J Clin Med        ISSN: 2077-0383            Impact factor:   4.241


  1 in total

1.  Editorial of Special Issue "Embolization Techniques: State of the Art and Future Perspectives".

Authors:  Massimo Venturini; Filippo Piacentino; Andrea Coppola; Federico Fontana
Journal:  J Clin Med       Date:  2022-08-30       Impact factor: 4.964

  1 in total

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