The aim of this study is to report on the oral lesions detected in 123 patients diagnosed at the University Hospital of Bari from October 2020 to December 2020, focusing on the correlation of clinical and pathological features in order to purpose a new classification. METHODS: General and specialistic anamnesis were achieved and oral examination was performed. The following data were collected: age/gender, general symptoms and form of Covid-19, presence and features of taste disorders, day of appearance of the oral lesions, type and features of oral lesions and day of beginning of therapies. If ulcerative lesions did not heal, biopsy was performed. RESULTS: Many types of oral lesions were found and classified into four groups considering the timing of appearance and the start of the therapies. Early lesions in the initial stages of Covid-19 before the start of therapies was observed in 65.9% of the patients. In the histopathological analysis of four early lesions, thrombosis of small and middle size vessels was always noticed with necrosis of superficial tissues. CONCLUSION: The presence of oral lesions in early stages of Covid-19 could represent an initial sign of peripheral thrombosis, a warning sign of possible evolution to severe illness. This suggests that anticoagulant therapies should start as soon as possible.
The aim of this study is to report on the oral lesions detected in 123 patients diagnosed at the University Hospital of Bari from October 2020 to December 2020, focusing on the correlation of clinical and pathological features in order to purpose a new classification. METHODS: General and specialistic anamnesis were achieved and oral examination was performed. The following data were collected: age/gender, general symptoms and form of Covid-19, presence and features of taste disorders, day of appearance of the oral lesions, type and features of oral lesions and day of beginning of therapies. If ulcerative lesions did not heal, biopsy was performed. RESULTS: Many types of oral lesions were found and classified into four groups considering the timing of appearance and the start of the therapies. Early lesions in the initial stages of Covid-19 before the start of therapies was observed in 65.9% of the patients. In the histopathological analysis of four early lesions, thrombosis of small and middle size vessels was always noticed with necrosis of superficial tissues. CONCLUSION: The presence of oral lesions in early stages of Covid-19 could represent an initial sign of peripheral thrombosis, a warning sign of possible evolution to severe illness. This suggests that anticoagulant therapies should start as soon as possible.
Authors: Giulia Orilisi; Marco Mascitti; Lucrezia Togni; Riccardo Monterubbianesi; Vincenzo Tosco; Flavia Vitiello; Andrea Santarelli; Angelo Putignano; Giovanna Orsini Journal: Int J Environ Res Public Health Date: 2021-11-27 Impact factor: 3.390
Authors: Gabriela Schwab; Michelle Palmieri; Rodrigo M Zerbinati; Dmitry J S Sarmento; Thais Reis; Karem L Ortega; Italo T Kano; Rafael A V Caixeta; Bengt Hasséus; Dipak Sapkota; Roger Junges; Simone Giannecchini; André L F Costa; Sumatra M C P Jales; José A L Lindoso; Camila Barros Gallo; Paulo H Braz-Silva Journal: J Oral Microbiol Date: 2022-03-10 Impact factor: 5.474
Authors: Trishnika Chakraborty; Rizwana Fathima Jamal; Gopi Battineni; Kavalipurapu Venkata Teja; Carlos Miguel Marto; Gianrico Spagnuolo Journal: Int J Environ Res Public Health Date: 2021-05-12 Impact factor: 3.390
Authors: María Verónica Cuevas-Gonzalez; León Francisco Espinosa-Cristóbal; Alejandro Donohue-Cornejo; Karla Lizette Tovar-Carrillo; Rosa Alicia Saucedo-Acuña; Alma Graciela García-Calderón; Dalia Abril Guzmán-Gastelum; Juan Carlos Cuevas-Gonzalez Journal: Medicine (Baltimore) Date: 2021-12-23 Impact factor: 1.817