Literature DB >> 3366692

Chemical modification of steffimycin B.

P F Wiley1, D W Elrod, D E Harper.   

Abstract

Fifteen 3-substituted analogues of steffimycin B (1) have been synthesized and their activity against P388 murine leukemia has been determined. Three of these were substantially more active than the parent compound.

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Year:  1988        PMID： 3366692     DOI： 10.7164/antibiotics.41.343

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  1 in total

1.  Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.

Authors:  Sonia Gullón; Carlos Olano; Mohamed S Abdelfattah; Alfredo F Braña; Jürgen Rohr; Carmen Méndez; José A Salas
Journal:  Appl Environ Microbiol       Date:  2006-06       Impact factor: 4.792
  1 in total

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