Literature DB >> 3366655

Autoradiographic studies on glucose utilization in individual zones of the rat thymus.

J B Warchol1, C Pilgrim, W J Ginda, R Brelińska.   

Abstract

Wistar rats were injected intraperitoneally with 2-(14C)deoxyglucose and their thymuses were processed for thaw-mount autoradiography after 5, 10 or 35 min. Highest levels of radioactivity were demonstrated in the thymic medulla (5-fold higher than in the cortex). Scanning of autoradiograms for regional differences in grain densities indicated particularly intense glucose utilization in the cortico-medullary zone. Differences in glucose utilization between individual thymic zones seem to reflect differences in cellular composition, i.e., ratio of stroma cells to thymocytes.

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Year:  1988        PMID： 3366655     DOI： 10.1007/bf00570326

Source DB:  PubMed          Journal:  Histochemistry        ISSN： 0301-5564


  9 in total

1.  Altered protein hypothesis of mammalian ageing processed-I. Thermal stability of glucose-6-phosphate dehydrogenase in C57BL/6J mouse tissue.

Authors:  J H Wulf; R G Cutler
Journal:  Exp Gerontol       Date:  1975-04       Impact factor: 4.032

2.  The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat.

Authors:  L Sokoloff; M Reivich; C Kennedy; M H Des Rosiers; C S Patlak; K D Pettigrew; O Sakurada; M Shinohara
Journal:  J Neurochem       Date:  1977-05       Impact factor: 5.372

3.  Ultrastructure of the rat thymus. A transmission, scanning electron microscope, and morphometric study.

Authors:  W S Hwang; T Y Ho; S C Luk; G T Simon
Journal:  Lab Invest       Date:  1974-11       Impact factor: 5.662

4.  Leukocyte energy metabolism. 3. Anaerobic and aerobic ATP production and related enzymes.

Authors:  M Jemelin; J Frei
Journal:  Enzymol Biol Clin (Basel)       Date:  1970

5.  Distribution of different cell types within the rat thymus in the neonatal period of life.

Authors:  R Brelińska; E Kaczmarek; J B Warchoł; J Jaroszewski
Journal:  Cell Tissue Res       Date:  1985       Impact factor: 5.249

6.  Identification of early stages of T lymphocyte development in the thymus cortex and medulla.

Authors:  R Scollay; K Shortman
Journal:  J Immunol       Date:  1985-06       Impact factor: 5.422

7.  Improving the resolution of the 2-deoxy-D-glucose method.

Authors:  C Pilgrim; H J Wagner
Journal:  J Histochem Cytochem       Date:  1981-01       Impact factor: 2.479

8.  Evidence for a blood-thymus barrier using electron-opaque tracers.

Authors:  E Raviola; M J Karnovsky
Journal:  J Exp Med       Date:  1972-09-01       Impact factor: 14.307

9.  Thymic hormone-containing cells. Characterization and localization of serum thymic factor in young mouse thymus studied by monoclonal antibodies.

Authors:  W Savino; M Dardenne; M Papiernik; J F Bach
Journal:  J Exp Med       Date:  1982-08-01       Impact factor: 14.307
  9 in total
  1 in total

1.  Thymic nurse cells: division of thymocytes within complexes.

Authors:  R Brelińska
Journal:  Cell Tissue Res       Date:  1989-12       Impact factor: 5.249
  1 in total

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