Literature DB >> 3366645

An improved procedure for background correction in autoradiography.

H Korr1, H Schmidt.   

Abstract

In the event of weak autoradiographic labelling, the proportion of truly labelled cells or structures can be calculated from the frequency distributions of grains per area or cell structure for i = 0, 1,..., n grains using the results obtained for an experimental group after the application of a radioactively labelled substance and those obtained for a control group without radioactivity. The principle of this computer-aided method is also applicable when the grain counts are related to varying areas in histological sections.

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Substances：

Year:  1988        PMID： 3366645     DOI： 10.1007/bf00570302

Source DB:  PubMed          Journal:  Histochemistry        ISSN： 0301-5564


  10 in total

1.  GRAIN COUNT CORRECTIONS IN AUTORADIOGRAPHY--II.

Authors:  J STILLSTROEM
Journal:  Int J Appl Radiat Isot       Date:  1965-06

2.  Grain count corrections in autoradiography.

Authors:  J STILLSTROM
Journal:  Int J Appl Radiat Isot       Date:  1963-03

3.  Localization of cholinergic muscarinic receptors in rat brain by light microscopic radioautography.

Authors:  M Kuhar; H I Yamamura
Journal:  Brain Res       Date:  1976-07-09       Impact factor: 3.252

4.  Investigation of glial cells in semithin sections. I. Identification of glial cells in the brain of young rats.

Authors:  E A Ling; J A Paterson; A Privat; S Mori; C P Leblond
Journal:  J Comp Neurol       Date:  1973-05-01       Impact factor: 3.215

5.  Perfusion-fixation, colchicine and mitotic activity in the adult rat brain.

Authors:  J B Cavanagh; P D Lewis
Journal:  J Anat       Date:  1969-03       Impact factor: 2.610

6.  Computer subtraction of background in autoradiography with tritiated thymidine.

Authors:  M Benassi; R Paoluzi; F Bresciani
Journal:  Cell Tissue Kinet       Date:  1973-01

7.  The statistical analysis of autoradiographs. I. Grain count distributions over uniformly labelled sources.

Authors:  J M England; A W Rogers
Journal:  J Microsc       Date:  1970       Impact factor: 1.758

8.  Correction of autoradiographic grain count in respect to precisely calculated background.

Authors:  W Sawicki; O Blaton; J Rowiński
Journal:  Histochemie       Date:  1971

9.  Science and art in preparing tissues embedded in plastic for light microscopy, with special reference to glycol methacrylate, glass knives and simple stains.

Authors:  H S Bennett; A D Wyrick; S W Lee; J H McNeil
Journal:  Stain Technol       Date:  1976-03

10.  The identification of labelled structures on autoradiographs.

Authors:  J M England; A W Rogers; R G Miller
Journal:  Nature       Date:  1973-04-27       Impact factor: 49.962
  10 in total
  2 in total

Review 1.  Accumulation of nuclear DNA damage or neuron loss: molecular basis for a new approach to understanding selective neuronal vulnerability in neurodegenerative diseases.

Authors:  Ivona Brasnjevic; Patrick R Hof; Harry W M Steinbusch; Christoph Schmitz
Journal:  DNA Repair (Amst)       Date:  2008-05-23

2.  X-ray dose-effect relationship on unscheduled DNA synthesis and spontaneous unscheduled DNA synthesis in mouse brain cells studied in vivo.

Authors:  H Korr; K Koeser; S Oldenkott; H Schmidt; B Schultze
Journal:  Radiat Environ Biophys       Date:  1989       Impact factor: 1.925
  2 in total

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