Literature DB >> 33663498

Excess mortality for care home residents during the first 23 weeks of the COVID-19 pandemic in England: a national cohort study.

Marcello Morciano1,2, Jonathan Stokes3,4, Evangelos Kontopantelis4,5, Ian Hall5,6, Alex J Turner3,4.   

Abstract

BACKGROUND: To estimate excess mortality for care home residents during the COVID-19 pandemic in England, exploring associations with care home characteristics.
METHODS: Daily number of deaths in all residential and nursing homes in England notified to the Care Quality Commission (CQC) from 1 January 2017 to 7 August 2020. Care home-level data linked with CQC care home register to identify home characteristics: client type (over 65s/children and adults), ownership status (for-profit/not-for-profit; branded/independent) and size (small/medium/large). Excess deaths computed as the difference between observed and predicted deaths using local authority fixed-effect Poisson regressions on pre-pandemic data. Fixed-effect logistic regressions were used to model odds of experiencing COVID-19 suspected/confirmed deaths.
RESULTS: Up to 7 August 2020, there were 29,542 (95% CI 25,176 to 33,908) excess deaths in all care homes. Excess deaths represented 6.5% (95% CI 5.5 to 7.4%) of all care home beds, higher in nursing (8.4%) than residential (4.6%) homes. 64.7% (95% CI 56.4 to 76.0%) of the excess deaths were confirmed/suspected COVID-19. Almost all excess deaths were recorded in the quarter (27.4%) of homes with any COVID-19 fatalities. The odds of experiencing COVID-19 attributable deaths were higher in homes providing nursing services (OR 1.8, 95% CI 1.6 to 2.0), to older people and/or with dementia (OR 5.5, 95% CI 4.4 to 6.8), amongst larger (vs. small) homes (OR 13.3, 95% CI 11.5 to 15.4) and belonging to a large provider/brand (OR 1.2, 95% CI 1.1 to 1.3). There was no significant association with for-profit status of providers.
CONCLUSIONS: To limit excess mortality, policy should be targeted at care homes to minimise the risk of ingress of disease and limit subsequent transmission. Our findings provide specific characteristic targets for further research on mechanisms and policy priority.

Entities:  

Keywords:  COVID-19; Care homes; England; Excess deaths

Mesh:

Year:  2021        PMID: 33663498      PMCID: PMC7932761          DOI: 10.1186/s12916-021-01945-2

Source DB:  PubMed          Journal:  BMC Med        ISSN: 1741-7015            Impact factor:   8.775


  13 in total

1.  David Oliver: Preventing more deaths in care homes in a second pandemic surge.

Authors:  David Oliver
Journal:  BMJ       Date:  2020-06-23

2.  Association of Nursing Home Ratings on Health Inspections, Quality of Care, and Nurse Staffing With COVID-19 Cases.

Authors:  Jose F Figueroa; Rishi K Wadhera; Irene Papanicolas; Kristen Riley; Jie Zheng; E John Orav; Ashish K Jha
Journal:  JAMA       Date:  2020-09-15       Impact factor: 56.272

3.  Covid-19: Lack of capacity led to halting of community testing in March, admits deputy chief medical officer.

Authors:  Gareth Iacobucci
Journal:  BMJ       Date:  2020-05-06

4.  COVID-19 in Nursing Homes: Calming the Perfect Storm.

Authors:  Joseph G Ouslander; David C Grabowski
Journal:  J Am Geriatr Soc       Date:  2020-09-02       Impact factor: 5.562

5.  Excess Deaths From COVID-19 and Other Causes, March-April 2020.

Authors:  Steven H Woolf; Derek A Chapman; Roy T Sabo; Daniel M Weinberger; Latoya Hill
Journal:  JAMA       Date:  2020-08-04       Impact factor: 157.335

6.  The Impact of COVID-19 Measures on Well-Being of Older Long-Term Care Facility Residents in the Netherlands.

Authors:  Henriëtte G Van der Roest; Marleen Prins; Claudia van der Velden; Stephanie Steinmetz; Elske Stolte; Theo G van Tilburg; Danny H de Vries
Journal:  J Am Med Dir Assoc       Date:  2020-09-10       Impact factor: 4.669

7.  Risk factors for outbreaks of COVID-19 in care homes following hospital discharge: A national cohort analysis.

Authors:  Chris Emmerson; James P Adamson; Drew Turner; Mike B Gravenor; Jane Salmon; Simon Cottrell; Victoria Middleton; Buffy Thomas; Brendan W Mason; Chris J Williams
Journal:  Influenza Other Respir Viruses       Date:  2021-02-06       Impact factor: 5.606

8.  Excess mortality in England and Wales during the first wave of the COVID-19 pandemic.

Authors:  Evangelos Kontopantelis; Mamas A Mamas; John Deanfield; Miqdad Asaria; Tim Doran
Journal:  J Epidemiol Community Health       Date:  2020-10-15       Impact factor: 3.710

9.  For-profit long-term care homes and the risk of COVID-19 outbreaks and resident deaths.

Authors:  Nathan M Stall; Aaron Jones; Kevin A Brown; Paula A Rochon; Andrew P Costa
Journal:  CMAJ       Date:  2020-07-22       Impact factor: 8.262

10.  High prevalence of SARS-CoV-2 antibodies in care homes affected by COVID-19: Prospective cohort study, England.

Authors:  Shamez N Ladhani; Anna Jeffery-Smith; Monika Patel; Roshni Janarthanan; Jonathan Fok; Emma Crawley-Boevey; Amoolya Vusirikala; Elena Fernandez Ruiz De Olano; Marina Sanchez Perez; Suzanne Tang; Kate Dun-Campbell; Edward Wynne- Evans; Anita Bell; Bharat Patel; Zahin Amin-Chowdhury; Felicity Aiano; Karthik Paranthaman; Thomas Ma; Maria Saavedra-Campos; Joanna Ellis; Meera Chand; Kevin Brown; Mary E Ramsay; Susan Hopkins; Nandini Shetty; J Yimmy Chow; Robin Gopal; Maria Zambon
Journal:  EClinicalMedicine       Date:  2020-11-06
View more
  29 in total

1.  What does a pandemic proof health system look like?

Authors:  Janet Michel; Thomas C Sauter; Marcel Tanner
Journal:  Glob Health Action       Date:  2021-01-01       Impact factor: 2.640

2.  Duration of vaccine effectiveness against SARS-CoV-2 infection, hospitalisation, and death in residents and staff of long-term care facilities in England (VIVALDI): a prospective cohort study.

Authors:  Madhumita Shrotri; Maria Krutikov; Hadjer Nacer-Laidi; Borscha Azmi; Tom Palmer; Rebecca Giddings; Christopher Fuller; Aidan Irwin-Singer; Verity Baynton; Gokhan Tut; Paul Moss; Andrew Hayward; Andrew Copas; Laura Shallcross
Journal:  Lancet Healthy Longev       Date:  2022-07-04

3.  Infodemiological study on the impact of the COVID-19 pandemic on increased headache incidences at the world level.

Authors:  Cristiana Tudor; Robert Sova
Journal:  Sci Rep       Date:  2022-06-17       Impact factor: 4.996

4.  COVID-19 - exploring the implications of long-term condition type and extent of multimorbidity on years of life lost: a modelling study.

Authors:  Peter Hanlon; Fergus Chadwick; Anoop Shah; Rachael Wood; Jon Minton; Gerry McCartney; Colin Fischbacher; Frances S Mair; Dirk Husmeier; Jason Matthiopoulos; David A McAllister
Journal:  Wellcome Open Res       Date:  2021-03-01

5.  Care-home outbreaks of COVID-19 in Scotland March to May 2020: National linked data cohort analysis.

Authors:  Jennifer Kirsty Burton; Megan McMinn; James E Vaughan; Jacques Fleuriot; Bruce Guthrie
Journal:  Age Ageing       Date:  2021-09-11       Impact factor: 10.668

6.  Previous SARS-CoV-2 Infection, Age, and Frailty Are Associated With 6-Month Vaccine-Induced Anti-Spike Antibody Titer in Nursing Home Residents.

Authors:  Adam H Dyer; Claire Noonan; Matt McElheron; Isabella Batten; Conor Reddy; Emma Connolly; Rachel Pierpoint; Caroline Murray; Ann Leonard; Catriona Higgins; Phyllis Reilly; Gerard Boran; Thomas Phelan; William McCormack; Desmond O'Neill; Aoife Fallon; Gareth Brady; Cliona O'Farrelly; Nollaig M Bourke; Sean P Kennelly
Journal:  J Am Med Dir Assoc       Date:  2022-01-11       Impact factor: 7.802

7.  Mortality among Care Home Residents in England during the first and second waves of the COVID-19 pandemic: an observational study of 4.3 million adults over the age of 65.

Authors:  Anna Schultze; Emily Nightingale; David Evans; William Hulme; Alicia Rosello; Chris Bates; Jonathan Cockburn; Brian MacKenna; Helen J Curtis; Caroline E Morton; Richard Croker; Seb Bacon; Helen I McDonald; Christopher T Rentsch; Krishnan Bhaskaran; Rohini Mathur; Laurie A Tomlinson; Elizabeth J Williamson; Harriet Forbes; John Tazare; Daniel Grint; Alex J Walker; Peter Inglesby; Nicholas J DeVito; Amir Mehrkar; George Hickman; Simon Davy; Tom Ward; Louis Fisher; Amelia Ca Green; Kevin Wing; Angel Ys Wong; Robert McManus; John Parry; Frank Hester; Sam Harper; Stephen Jw Evans; Ian J Douglas; Liam Smeeth; Rosalind M Eggo; Ben Goldacre; David A Leon
Journal:  Lancet Reg Health Eur       Date:  2022-01-10

8.  Factors associated with excess all-cause mortality in the first wave of the COVID-19 pandemic in the UK: A time series analysis using the Clinical Practice Research Datalink.

Authors:  Helen Strongman; Helena Carreira; Bianca L De Stavola; Krishnan Bhaskaran; David A Leon
Journal:  PLoS Med       Date:  2022-01-06       Impact factor: 11.069

9.  Hospital admissions from care homes in England during the COVID-19 pandemic: a retrospective, cross-sectional analysis using linked administrative data.

Authors:  Fiona Grimm; Karen Hodgson; Richard Brine; Sarah R Deeny
Journal:  Int J Popul Data Sci       Date:  2021-07-08

10.  COVID-19 excess mortality among long-term care residents in Ontario, Canada.

Authors:  Noori Akhtar-Danesh; Andrea Baumann; Mary Crea-Arsenio; Valentina Antonipillai
Journal:  PLoS One       Date:  2022-01-20       Impact factor: 3.240

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.