Literature DB >> 3366239

VLDL apoprotein secretion and apo-B mRNA level in primary culture of cholesterol-loaded rabbit hepatocytes.

V A Kosykh1, A P Surguchov, E A Podres, D K Novikov, A B Sudarickov, V S Repin, V N Smirnov.   

Abstract

Incubation of cultured rabbit hepatocytes with beta very low density lipoproteins (beta-VLDL) induces a dose-dependent increase in cell cholesterol (CH) content and VLDL apoprotein (apo) B and E secretion without change in apo-B mRNA level. These data suggest that beta-VLDL may exert a stimulatory effect on hepatic apo-B production at the co-translational and/or posttranslational level.

Entities:  

Mesh:

Substances:

Year:  1988        PMID: 3366239     DOI: 10.1016/0014-5793(88)80395-8

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  1 in total

1.  A genetic model for control of hypertriglyceridemia and apolipoprotein B levels in the Johns Hopkins colony of St. Thomas Hospital rabbits.

Authors:  T H Beaty; V L Prenger; D G Virgil; B Lewis; P O Kwiterovich; P S Bachorik
Journal:  Genetics       Date:  1992-12       Impact factor: 4.562

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.