Literature DB >> 33661320

Vaginoplasty: modified McIndoe using xenograft and a tailored 3D-printer mold.

Lucila I Pavan1,2, Geronimo A Bourguignon3,4, Enrique P Ubertazzi3,4.   

Abstract

INTRODUCTION AND HYPOTHESIS: Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is the congenital absence of the vagina with variable uterine development. Different methods have been reported for vaginoplasty treatment. The preferred vaginal approach to treating this condition is usually McIndoe vaginoplasty supported by regular dilatation of the neovagina. We present a case video of a McIndoe modified vaginoplasty technique with a heterologous graft using a covering customized 3D-printed mold, its postoperative follow-up and postoperative complications.
METHODS: Video presentation of a McIndoe modified vaginoplasty technique using porcine intestinal submucosa performed in a 18-year-old woman diagnosed with MRKH syndrome. Different sizes of a polylactic acid mold were manufactured with 3D printers. After dissection of the recto-vesical space, a mold tailored in terms of length and width was chosen for this patient.
RESULTS: After 13 days of follow-up, the patient presented graft infection and subsequent total graft detachment. However, the patient continued to use the vaginal dilator permanently. After 7 months, 8 cm vaginal length with 90% epithelialization and satisfactory sexual intercourse were achieved.
CONCLUSION: Functional, histological and anatomical results were reached despite the graft detachment. New technologies such as 3D printing facilitate the development of techniques using tailored molds.
© 2021. The International Urogynecological Association.

Entities:  

Keywords:  Modified McIndoe; Neovagina; Polylactic acid mold; Rokitansky; Tailored mold; Vaginal agenesis; Vaginoplasty; Xenograft

Year:  2021        PMID: 33661320     DOI: 10.1007/s00192-021-04689-y

Source DB:  PubMed          Journal:  Int Urogynecol J        ISSN: 0937-3462            Impact factor:   2.894


  1 in total

1.  Prevalence and patient characteristics of Mayer-Rokitansky-Küster-Hauser syndrome: a nationwide registry-based study.

Authors:  Morten Herlin; Anne-Mette Bay Bjørn; Maria Rasmussen; Birgitta Trolle; Michael Bjørn Petersen
Journal:  Hum Reprod       Date:  2016-09-08       Impact factor: 6.918

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.