| Literature DB >> 336592 |
T Nakanishi, F Tomita, A Furuya.
Abstract
The antibacterial activity of a new nucleoside antibiotic, 2'-amino-2'-deoxyguanosine (2AG), is reversed by guanosine and other purine nucleosides. 2AG is apparently taken up by E. coli by a mechanism different from that of guanosine; guanosine inhibits this uptake non-competitively. Insensitive E. coli strains and the resistant mutant obtained from the sensitive strain also took up 2AG.Entities:
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Year: 1977 PMID： 336592 DOI： 10.7164/antibiotics.30.736
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649