Literature DB >> 33657389

Passing on PCOS: new insights into its epigenetic transmission.

David H Abbott1, Daniel A Dumesic2.   

Abstract

Polycystic ovary syndrome (PCOS) is a prevalent reproductive-metabolic disorder with poorly understood etiology. Mimouni et al. (2021) demonstrate global genomic DNA hypomethylation in women with PCOS and their daughters, and in F3 generation PCOS-like mice, together with substantial normalization of PCOS-like mice by methyl donor dietary supplementation.
Copyright © 2021 Elsevier Inc. All rights reserved.

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Year:  2021        PMID: 33657389      PMCID: PMC9133658          DOI: 10.1016/j.cmet.2021.02.008

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   31.373


  8 in total

1.  Circulating antimüllerian hormone and steroid hormone levels remain high in pregnant women with polycystic ovary syndrome at term.

Authors:  Terhi T Piltonen; Paolo Giacobini; Åsa Edvinsson; Steinar Hustad; Susanne Lager; Laure Morin-Papunen; Juha S Tapanainen; Inger Sundström-Poromaa; Riikka K Arffman
Journal:  Fertil Steril       Date:  2019-01-07       Impact factor: 7.329

Review 2.  Animal Models to Understand the Etiology and Pathophysiology of Polycystic Ovary Syndrome.

Authors:  Elisabet Stener-Victorin; Vasantha Padmanabhan; Kirsty A Walters; Rebecca E Campbell; Anna Benrick; Paolo Giacobini; Daniel A Dumesic; David H Abbott
Journal:  Endocr Rev       Date:  2020-07-01       Impact factor: 19.871

3.  Metabolic response to folate supplementation in overweight women with polycystic ovary syndrome: a randomized double-blind placebo-controlled clinical trial.

Authors:  Zatollah Asemi; Maryam Karamali; Ahmad Esmaillzadeh
Journal:  Mol Nutr Food Res       Date:  2014-05-15       Impact factor: 5.914

4.  The effects of folate supplementation on inflammatory factors and biomarkers of oxidative stress in overweight and obese women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled clinical trial.

Authors:  Fereshteh Bahmani; Maryam Karamali; Hossein Shakeri; Zatollah Asemi
Journal:  Clin Endocrinol (Oxf)       Date:  2014-04-15       Impact factor: 3.478

5.  The impact of a standardized micronutrient supplementation on PCOS-typical parameters: a randomized controlled trial.

Authors:  Marlene Hager; Kazem Nouri; Martin Imhof; Christian Egarter; Johannes Ott
Journal:  Arch Gynecol Obstet       Date:  2019-05-17       Impact factor: 2.344

6.  Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process.

Authors:  Nour El Houda Mimouni; Isabel Paiva; Anne-Laure Barbotin; Fatima Ezzahra Timzoura; Damien Plassard; Stephanie Le Gras; Gaetan Ternier; Pascal Pigny; Sophie Catteau-Jonard; Virginie Simon; Vincent Prevot; Anne-Laurence Boutillier; Paolo Giacobini
Journal:  Cell Metab       Date:  2021-02-03       Impact factor: 27.287

7.  Prenatal androgen exposure and transgenerational susceptibility to polycystic ovary syndrome.

Authors:  Sanjiv Risal; Yu Pei; Haojiang Lu; Maria Manti; Romina Fornes; Han-Pin Pui; Zhiyi Zhao; Julie Massart; Claes Ohlsson; Eva Lindgren; Nicolas Crisosto; Manuel Maliqueo; Barbara Echiburú; Amanda Ladrón de Guevara; Teresa Sir-Petermann; Henrik Larsson; Mina A Rosenqvist; Carolyn E Cesta; Anna Benrick; Qiaolin Deng; Elisabet Stener-Victorin
Journal:  Nat Med       Date:  2019-12-02       Impact factor: 53.440

8.  Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood.

Authors:  Brooke Tata; Nour El Houda Mimouni; Anne-Laure Barbotin; Samuel A Malone; Anne Loyens; Pascal Pigny; Didier Dewailly; Sophie Catteau-Jonard; Inger Sundström-Poromaa; Terhi T Piltonen; Federica Dal Bello; Claudio Medana; Vincent Prevot; Jerome Clasadonte; Paolo Giacobini
Journal:  Nat Med       Date:  2018-05-14       Impact factor: 53.440

  8 in total
  5 in total

1.  The Association Between Genetically Predicted Systemic Inflammatory Regulators and Polycystic Ovary Syndrome: A Mendelian Randomization Study.

Authors:  Hanxiao Chen; Yaoyao Zhang; Shangwei Li; Yuanzhi Tao; Rui Gao; Wenming Xu; Yihong Yang; Kemin Cheng; Yan Wang; Lang Qin
Journal:  Front Endocrinol (Lausanne)       Date:  2021-09-27       Impact factor: 5.555

2.  Transcriptional and DNA Methylation Signatures of Subcutaneous Adipose Tissue and Adipose-Derived Stem Cells in PCOS Women.

Authors:  Adeline Divoux; Edina Erdos; Katie Whytock; Timothy F Osborne; Steven R Smith
Journal:  Cells       Date:  2022-03-01       Impact factor: 6.600

3.  The PNA mouse may be the best animal model of polycystic ovary syndrome.

Authors:  Jingyi Ren; Guangqing Tan; Xinyi Ren; Weiyu Lu; Qiling Peng; Jing Tang; Yingxiong Wang; Biao Xie; Meijiao Wang
Journal:  Front Endocrinol (Lausanne)       Date:  2022-08-08       Impact factor: 6.055

4.  Effects of Bu Shen Hua Zhuo formula on the LPS/TLR4 pathway and gut microbiota in rats with letrozole-induced polycystic ovary syndrome.

Authors:  Yang Wang; Hui Xiao; Yanxia Liu; Qing Tong; Yanyan Yu; Bing Qi; Xiaoling Bu; Tianyuan Pan; Yu Xing
Journal:  Front Endocrinol (Lausanne)       Date:  2022-08-09       Impact factor: 6.055

5.  The complex metabolic interactions of liver tissue and hepatic exosome in PCOS mice at young and middle age.

Authors:  ShanHu Gao; Fei Long; Zheng Jiang; Jun Shi; DongXue Ma; Yang Yang; Jin Bai; Ting-Li Han
Journal:  Front Physiol       Date:  2022-09-20       Impact factor: 4.755

  5 in total

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