A Calin1, J Elswood. 1. Royal National Hospital for Rheumatic Diseases, Upper Borough Walls, Bath, UK.
Abstract
UNLABELLED: One hundred and thirty-five patients with juvenile-onset ankylosing spondylitis (JAS: less than 16 years at onset, mean 12.8 years) were compared to 135 adult-onset spondylitics (AAS: greater than 21 years at onset, mean 26.1 years), controlled for disease duration (24.5 and 23.5 years, respectively), to assess the outcome of juvenile-onset disease. Review was by postal questionnaire and health-assessment measures. The sex distribution was similar: 73% and 74% males, respectively. All parameters showed comparable outcome with the exception of the numbers in full-time employment (JAS 74%, AAS 56%; p less than 0.01) and total hip replacements (JAS 17%, AAS 4%; p less than 0.01). IN CONCLUSION: (a) the premature hip is particularly at risk in ankylosing spondylitis; (b) there are few differences between the outcome of JAS and AAS; (c) overall, JAS patients do well in adulthood.
UNLABELLED: One hundred and thirty-five patients with juvenile-onset ankylosing spondylitis (JAS: less than 16 years at onset, mean 12.8 years) were compared to 135 adult-onset spondylitics (AAS: greater than 21 years at onset, mean 26.1 years), controlled for disease duration (24.5 and 23.5 years, respectively), to assess the outcome of juvenile-onset disease. Review was by postal questionnaire and health-assessment measures. The sex distribution was similar: 73% and 74% males, respectively. All parameters showed comparable outcome with the exception of the numbers in full-time employment (JAS 74%, AAS 56%; p less than 0.01) and total hip replacements (JAS 17%, AAS 4%; p less than 0.01). IN CONCLUSION: (a) the premature hip is particularly at risk in ankylosing spondylitis; (b) there are few differences between the outcome of JAS and AAS; (c) overall, JASpatients do well in adulthood.
Authors: Filipa Oliveira Ramos; Ana Rodrigues; Fernando Magalhaes Martins; Ana Teresa Melo; Francisca Aguiar; Luisa Brites; Soraia Azevedo; Ana Catarina Duarte; Carolina Furtado; Ana Filipa Mourão; Graça Sequeira; Inês Cunha; Ricardo Figueira; Jose Antonio Melo Gomes; Maria Jose Santos; Joao Eurico Fonseca Journal: RMD Open Date: 2021-11