Literature DB >> 33655088

LUCIA: An open source device for disinfection of N95 masks using UV-C radiation.

Marcel Bentancor1, Sebastián Fernández2, Federico Viera3, Sarita Etcheverry3, Carolina Poradosú3, Pablo D'Angelo3, Hernán Montemuiño3, Santiago Mirazo4, Álvaro Irigoyen5, Analía Sanabria6, Horacio Failache7.   

Abstract

Faced with a global pandemic such as the one triggered by the SARS-CoV-2 virus, the medical supply chain has been highly demanded. An item in which this manifested itself more clearly, are the N95 masks, designed to be disposable items, in many cases they have had to be reused. In these emergency conditions, it was necessary to apply an effective and safe method that can be used locally. Here a device for disinfection by ultraviolet C light was developed that allows irradiating N95 masks with a known and reproducible dose. Thus being able to apply a safe and effective disinfection method according to existing information. The use of a common model of UV-C lamps and the simple construction of the device allows it to be built at low cost and with widely available materials. The effectiveness of the device was demonstrated against an enveloped RNA virus, characteristics shared with the virus that causes COVID19, being capable of reducing the viral load by 4 orders of magnitude.
© 2021 The Authors.

Entities:  

Keywords:  COVID19; Pandemic; SARS-CoV-2; Virucide

Year:  2021        PMID: 33655088      PMCID: PMC7906873          DOI: 10.1016/j.ohx.2021.e00181

Source DB:  PubMed          Journal:  HardwareX        ISSN: 2468-0672


  24 in total

1.  A method to determine the available UV-C dose for the decontamination of filtering facepiece respirators.

Authors:  E M Fisher; R E Shaffer
Journal:  J Appl Microbiol       Date:  2010-11-04       Impact factor: 3.772

2.  The effects of ultraviolet radiation on antibiotic-resistant bacteria in vitro.

Authors:  T A Conner-Kerr; P K Sullivan; J Gaillard; M E Franklin; R M Jones
Journal:  Ostomy Wound Manage       Date:  1998-10       Impact factor: 2.629

3.  UV inactivation of pathogenic and indicator microorganisms.

Authors:  J C Chang; S F Ossoff; D C Lobe; M H Dorfman; C M Dumais; R G Qualls; J D Johnson
Journal:  Appl Environ Microbiol       Date:  1985-06       Impact factor: 4.792

4.  Effects of Ultraviolet Germicidal Irradiation (UVGI) on N95 Respirator Filtration Performance and Structural Integrity.

Authors:  William G Lindsley; Stephen B Martin; Robert E Thewlis; Khachatur Sarkisian; Julian O Nwoko; Kenneth R Mead; John D Noti
Journal:  J Occup Environ Hyg       Date:  2015       Impact factor: 2.155

5.  Effectiveness of Ultraviolet-C Light and a High-Level Disinfection Cabinet for Decontamination of N95 Respirators.

Authors:  Jennifer L Cadnum; Daniel F Li; Sarah N Redmond; Amrita R John; Basya Pearlmutter; Curtis J Donskey
Journal:  Pathog Immun       Date:  2020-04-20

6.  Ultraviolet germicidal irradiation of influenza-contaminated N95 filtering facepiece respirators.

Authors:  Devin Mills; Delbert A Harnish; Caryn Lawrence; Megan Sandoval-Powers; Brian K Heimbuch
Journal:  Am J Infect Control       Date:  2018-04-17       Impact factor: 2.918

Review 7.  Evidence for decontamination of single-use filtering facepiece respirators.

Authors:  A Polkinghorne; J Branley
Journal:  J Hosp Infect       Date:  2020-05-27       Impact factor: 3.926

8.  The effect of ultraviolet C radiation against different N95 respirators inoculated with SARS-CoV-2.

Authors:  David M Ozog; Jonathan Z Sexton; Shanthi Narla; Carla D Pretto-Kernahan; Carmen Mirabelli; Henry W Lim; Iltefat H Hamzavi; Robert J Tibbetts; Qing-Sheng Mi
Journal:  Int J Infect Dis       Date:  2020-09-03       Impact factor: 3.623

9.  Preparing for an Influenza Pandemic: Hospital Acceptance Study of Filtering Facepiece Respirator Decontamination Using Ultraviolet Germicidal Irradiation.

Authors:  Christopher Nemeth; Dawn Laufersweiler; Emily Polander; Christianna Orvis; Del Harnish; Sherwin E Morgan; Michael O'Connor; Saul Hymes; Sharon Nachman; Brian Heimbuch
Journal:  J Patient Saf       Date:  2020-06       Impact factor: 2.243

Review 10.  Decontamination of N95 respirators against SARS-CoV-2: A scoping review.

Authors:  Rafael Sarkis-Onofre; Rafaela do Carmo Borges; Giulia Demarco; Lara Dotto; Falk Schwendicke; Flávio Fernando Demarco
Journal:  J Dent       Date:  2020-11-13       Impact factor: 4.379

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  1 in total

1.  Ultraviolet-C Irradiation, Heat, and Storage as Potential Methods of Inactivating SARS-CoV-2 and Bacterial Pathogens on Filtering Facepiece Respirators.

Authors:  Rhodri Harfoot; Deborah B Y Yung; William A Anderson; Cervantée E K Wild; Nicolene Coetzee; Leonor C Hernández; Blair Lawley; Daniel Pletzer; José G B Derraik; Yvonne C Anderson; Miguel E Quiñones-Mateu
Journal:  Pathogens       Date:  2022-01-10
  1 in total

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