Literature DB >> 33654726

Bone-in-culture Array to Model Bone Metastasis in ex vivo Condition.

Hai Wang1,2, Xiang H-F Zhang1,2,3,4.   

Abstract

Bone is the most frequently affected organ by metastases of breast cancer and prostate cancer. Our knowledge on bone metastasis is extremely limited due to the lack of potent and efficient experimental models. We developed the "Bone-In-Culture Array (BICA)" platform to model the bone colonization of cancer cells in ex vivo cultures. The use of the BICA platform will facilitate in-depth mechanistic studies and high-throughput screening of drugs for bone metastasis.
Copyright © 2020 The Authors; exclusive licensee Bio-protocol LLC.

Entities:  

Keywords:  Bone metastases; Bone-in-culture array; Breast cancer; Metastasis modeling; Prostate cancer; ex vivo

Year:  2020        PMID： 33654726      PMCID： PMC7842296          DOI： 10.21769/BioProtoc.3495

Source DB:  PubMed          Journal:  Bio Protoc        ISSN： 2331-8325


  10 in total

Review 1.  In vitro microenvironments to study breast cancer bone colonisation.

Authors:  Anna V Taubenberger
Journal:  Adv Drug Deliv Rev       Date:  2014-10-23       Impact factor: 15.470

2.  The Osteogenic Niche Is a Calcium Reservoir of Bone Micrometastases and Confers Unexpected Therapeutic Vulnerability.

Authors:  Hai Wang; Lin Tian; Jun Liu; Amit Goldstein; Igor Bado; Weijie Zhang; Benjamin R Arenkiel; Zonghai Li; Meng Yang; Shiyu Du; Hong Zhao; David R Rowley; Stephen T C Wong; Zbigniew Gugala; Xiang H-F Zhang
Journal:  Cancer Cell       Date:  2018-11-12       Impact factor: 31.743

3.  In vitro and in vivo model systems used in prostate cancer research.

Authors:  David Cunningham; Zongbing You
Journal:  J Biol Methods       Date:  2015

Review 4.  Animal Models of Bone Metastasis.

Authors:  J K Simmons; B E Hildreth; W Supsavhad; S M Elshafae; B B Hassan; W P Dirksen; R E Toribio; T J Rosol
Journal:  Vet Pathol       Date:  2015-05-28       Impact factor: 2.221

5.  Intra-iliac Artery Injection for Efficient and Selective Modeling of Microscopic Bone Metastasis.

Authors:  Cuijuan Yu; Hai Wang; Aaron Muscarella; Amit Goldstein; Huan-Chang Zeng; Yangjin Bae; Brendan H I Lee; Xiang H-F Zhang
Journal:  J Vis Exp       Date:  2016-09-26       Impact factor: 1.355

Review 6.  Breast cancer metastasis: markers and models.

Authors:  Britta Weigelt; Johannes L Peterse; Laura J van 't Veer
Journal:  Nat Rev Cancer       Date:  2005-08       Impact factor: 60.716

Review 7.  Rat models of bone metastases.

Authors:  Stéphane Blouin; Michel Félix Baslé; Daniel Chappard
Journal:  Clin Exp Metastasis       Date:  2006-05-03       Impact factor: 5.150

8.  The osteogenic niche promotes early-stage bone colonization of disseminated breast cancer cells.

Authors:  Hai Wang; Cuijuan Yu; Xia Gao; Thomas Welte; Aaron M Muscarella; Lin Tian; Hong Zhao; Zhen Zhao; Shiyu Du; Jianning Tao; Brendan Lee; Thomas F Westbrook; Stephen T C Wong; Xin Jin; Jeffrey M Rosen; C Kent Osborne; Xiang H-F Zhang
Journal:  Cancer Cell       Date:  2015-01-15       Impact factor: 31.743

9.  Bone-in-culture array as a platform to model early-stage bone metastases and discover anti-metastasis therapies.

Authors:  Hai Wang; Lin Tian; Amit Goldstein; Jun Liu; Hin-Ching Lo; Kuanwei Sheng; Thomas Welte; Stephen T C Wong; Zbigniew Gugala; Fabio Stossi; Chenghang Zong; Zonghai Li; Michael A Mancini; Xiang H-F Zhang
Journal:  Nat Commun       Date:  2017-04-21       Impact factor: 14.919

10.  A reliable murine model of bone metastasis by injecting cancer cells through caudal arteries.

Authors:  Takahiro Kuchimaru; Naoya Kataoka; Kenji Nakagawa; Tatsuhiro Isozaki; Hitomi Miyabara; Misa Minegishi; Tetsuya Kadonosono; Shinae Kizaka-Kondoh
Journal:  Nat Commun       Date:  2018-07-30       Impact factor: 14.919
  10 in total

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