Literature DB >> 33654718

Protocol for Measuring Free (Low-stress) Exploration in Rats.

Wojciech Pisula1, Klaudia Modlinska1.   

Abstract

Research on exploratory behavior plays a key part in behavioral science. Studying exploratory behavior of laboratory rodents may provide important data about many developmental and neurobiological processes occurring in animal ontogenesis. The proposed protocol for measuring the free (low-stress) exploration behavior in rats is straightforward, requires minimal resources and very little animal training. It can therefore be broadly applied to studying animal cognition, animal behavior in general, the aging processes, and several animal models of various phenomena.
Copyright © 2020 The Authors; exclusive licensee Bio-protocol LLC.

Entities:  

Keywords:  Exploratory activity; Free exploration paradigm; Habituation; Laboratory rodents; Response to novelty

Year:  2020        PMID: 33654718      PMCID: PMC7842670          DOI: 10.21769/BioProtoc.3485

Source DB:  PubMed          Journal:  Bio Protoc        ISSN: 2331-8325


  5 in total

1.  Molar characteristics of exploratory and investigatory behavior in the rat (Rattus norvegicus).

Authors:  M J Renner; C P Seltzer
Journal:  J Comp Psychol       Date:  1991-12       Impact factor: 2.231

2.  The Roman high- and low-avoidance rats respond differently to novelty in a familiarized environment.

Authors:  Wojciech Pisula
Journal:  Behav Processes       Date:  2003-06-30       Impact factor: 1.777

3.  Sex differences in investigatory and grooming behaviors of laboratory rats (Rattus norvegicus) following exposure to novelty.

Authors:  D H Thor; R J Harrison; S R Schneider; W J Carr
Journal:  J Comp Psychol       Date:  1988-06       Impact factor: 2.231

4.  Effect of environmental stressors on time course, variability and form of self-grooming in the rat: handling, social contact, defeat, novelty, restraint and fur moistening.

Authors:  A M van Erp; M R Kruk; W Meelis; D C Willekens-Bramer
Journal:  Behav Brain Res       Date:  1994-11-16       Impact factor: 3.332

5.  Behavioural Response to the Environmental Changes of Various Types in Lister-Hooded Male Rats.

Authors:  Wojciech Pisula; Klaudia Modlinska; Anna Chrzanowska
Journal:  Sci Rep       Date:  2019-05-08       Impact factor: 4.379

  5 in total
  3 in total

1.  Response to novelty induced by change in size and complexity of familiar objects in Lister-Hooded rats, a follow-up of 2019 study.

Authors:  Wojciech Pisula; Klaudia Modlinska; Anna Chrzanowska; Katarzyna Goncikowska
Journal:  Sci Rep       Date:  2021-05-13       Impact factor: 4.379

2.  Can the Hole-Board Test Predict a Rat's Exploratory Behavior in a Free-Exploration Test?

Authors:  Wojciech Pisula; Klaudia Modlinska; Katarzyna Goncikowska; Anna Chrzanowska
Journal:  Animals (Basel)       Date:  2021-04-09       Impact factor: 2.752

Review 3.  Roadbumps at the Crossroads of Integrating Behavioral and In Vitro Approaches for Neurotoxicity Assessment.

Authors:  G Jean Harry; Sandra McBride; Shannah K Witchey; Sakina Mhaouty-Kodja; Alain Trembleau; Matthew Bridge; Anna Bencsik
Journal:  Front Toxicol       Date:  2022-02-25
  3 in total

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