Mamy Mbelu1, Donatien Kayembe1, Luc Mokassa2, Jean-Jacques Malemba3. 1. Service de Biologie Clinique, Cliniques Universitaires de Kinshasa, Kinshasa, République démocratique du Congo. 2. Service d´Orthopédie, Cliniques Universitaires de Kinshasa, Kinshasa, République démocratique du Congo. 3. Service de Rhumatologie, Cliniques Universitaires de Kinshasa, Kinshasa, République démocratique du Congo.
Abstract
INTRODUCTION: the purpose of this study was to describe the profile of serum lipases in patients with bone fractures and to investigate the associated factors. METHODS: we conducted a cross-sectional study at the Kokolo Military General Hospital in Camp Kokolo (KMGHICK) from July to October 2013. All patients admitted with bone fractures who had agreed to take part in the study were included. The control group included voluntary blood donors. The parameters of interest were demographic characteristics, serum lipase, lipidogram, the site and the number of fractures. RESULTS: eighty-three patients were included in the study, they were all male subjects. Mean age of patients was 35.8±12.8 years; 78.3% of fractures were due to gunshot-related trauma. Femur was the most common seat of fractures (30%), followed by forearm (20%) and ulna (15%). Mean serum lipase concentration was 43.6 ± 2.9 IU/L (normal value: ≤38IU/L) in patients with fractures compared with 30.3 ± 2.3 IU/L in the control group (p<0.0001). CONCLUSION: a significantly higher rate of hyperlipasemia was found in patients with bone fractures compared with the control group. Hyperlipasemia was not associated with clinicobiological fatty embolism syndrome. Copyright: Mamy Mbelu et al.
INTRODUCTION: the purpose of this study was to describe the profile of serum lipases in patients with bone fractures and to investigate the associated factors. METHODS: we conducted a cross-sectional study at the Kokolo Military General Hospital in Camp Kokolo (KMGHICK) from July to October 2013. All patients admitted with bone fractures who had agreed to take part in the study were included. The control group included voluntary blood donors. The parameters of interest were demographic characteristics, serum lipase, lipidogram, the site and the number of fractures. RESULTS: eighty-three patients were included in the study, they were all male subjects. Mean age of patients was 35.8±12.8 years; 78.3% of fractures were due to gunshot-related trauma. Femur was the most common seat of fractures (30%), followed by forearm (20%) and ulna (15%). Mean serum lipase concentration was 43.6 ± 2.9 IU/L (normal value: ≤38IU/L) in patients with fractures compared with 30.3 ± 2.3 IU/L in the control group (p<0.0001). CONCLUSION: a significantly higher rate of hyperlipasemia was found in patients with bone fractures compared with the control group. Hyperlipasemia was not associated with clinicobiological fatty embolism syndrome. Copyright: Mamy Mbelu et al.
Authors: I A Naess; S C Christiansen; P Romundstad; S C Cannegieter; F R Rosendaal; J Hammerstrøm Journal: J Thromb Haemost Date: 2007-04 Impact factor: 5.824