Clément Medrinal1,2,3,4, Guillaume Prieur5,6,7,8, Tristan Bonnevie5,6,9, Francis-Edouard Gravier5,6,9, Denys Mayard10, Emmanuelle Desmalles10, Pauline Smondack9, Bouchra Lamia5,6,11,12, Yann Combret7,8, Guillaume Fossat10. 1. Normandie Univ, UNIROUEN, EA3830-GRHV, 76 000, Rouen, France. medrinal.clement.mk@gmail.com. 2. Institute for Research and Innovation in Biomedicine (IRIB), 76 000, Rouen, France. medrinal.clement.mk@gmail.com. 3. Intensive Care Unit Department, Groupe Hospitalier du Havre, Avenue Pierre Mendes France, 76290, Montivilliers, France. medrinal.clement.mk@gmail.com. 4. IFMK Saint Michel, 75015, Paris, France. medrinal.clement.mk@gmail.com. 5. Normandie Univ, UNIROUEN, EA3830-GRHV, 76 000, Rouen, France. 6. Institute for Research and Innovation in Biomedicine (IRIB), 76 000, Rouen, France. 7. Intensive Care Unit Department, Groupe Hospitalier du Havre, Avenue Pierre Mendes France, 76290, Montivilliers, France. 8. Research and Clinical Experimentation Institute (IREC), Pulmonology, ORL and Dermatology, Louvain Catholic University, 1200, Brussels, Belgium. 9. ADIR Association, Bois-Guillaume, France. 10. Service de Médecine Intensive Réanimation, Centre Hospitalier Régional d'Orléans, Orléans, France. 11. Pulmonology Department, Groupe Hospitalier du Havre, Avenue Pierre Mendes France, 76290, Montivilliers, France. 12. Pulmonology, Respiratory Department, Rouen University Hospital, Rouen, France.
Abstract
BACKGROUND: Few studies have evaluated muscle strength in COVID-19 ICU survivors. We aimed to report the incidence of limb and respiratory muscle weakness in COVID-19 ICU survivors. METHOD: We performed a cross sectional study in two ICU tertiary Hospital Settings. COVID-19 ICU survivors were screened and respiratory and limb muscle strength were measured at the time of extubation. An ICU mobility scale was performed at ICU discharge and walking capacity was self-evaluated by patients 30 days after weaning from mechanical ventilation. RESULTS: Twenty-three patients were included. Sixteen (69%) had limb muscle weakness and 6 (26%) had overlap limb and respiratory muscle weakness. Amount of physiotherapy was not associated with muscle strength. 44% of patients with limb weakness were unable to walk 100 m 30 days after weaning. CONCLUSION: The large majority of COVID-19 ICU survivors developed ICU acquired limb muscle weakness. 44% of patients with limb weakness still had severely limited function one-month post weaning.
BACKGROUND: Few studies have evaluated muscle strength in COVID-19 ICU survivors. We aimed to report the incidence of limb and respiratory muscle weakness in COVID-19 ICU survivors. METHOD: We performed a cross sectional study in two ICU tertiary Hospital Settings. COVID-19 ICU survivors were screened and respiratory and limb muscle strength were measured at the time of extubation. An ICU mobility scale was performed at ICU discharge and walking capacity was self-evaluated by patients 30 days after weaning from mechanical ventilation. RESULTS: Twenty-three patients were included. Sixteen (69%) had limb muscle weakness and 6 (26%) had overlap limb and respiratory muscle weakness. Amount of physiotherapy was not associated with muscle strength. 44% of patients with limb weakness were unable to walk 100 m 30 days after weaning. CONCLUSION: The large majority of COVID-19 ICU survivors developed ICU acquired limb muscle weakness. 44% of patients with limb weakness still had severely limited function one-month post weaning.
Entities:
Keywords:
COVID-19; Intensive care unit; Mechanical ventilation; Muscle weakness; Physiotherapy
Authors: Peter Thomas; Claire Baldwin; Lisa Beach; Bernie Bissett; Ianthe Boden; Sherene Magana Cruz; Rik Gosselink; Catherine L Granger; Carol Hodgson; Anne E Holland; Alice Ym Jones; Michelle E Kho; Lisa van der Lee; Rachael Moses; George Ntoumenopoulos; Selina M Parry; Shane Patman Journal: J Physiother Date: 2021-12-23 Impact factor: 7.000
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