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Literature DB >> 33651334

Characterization of Tendon-Derived Stem Cells and Rescue Tendon Injury.

Abstract

The natural healing ability of tendon is limited, and it cannot restore the native structure and function of tendon injuries. Tendon-derived stem cells (TDSCs) are a new type of pluripotent stem cells with multi-directional differentiation potential and are expected to become a promising cell-seed for the treatment of tendon injuries in the future. In this review, we outline the latest advances in the culture and identification of TDSCs. In addition, the influencing factors on the differentiation of TDSCs are discussed. Moreover, we aim to discuss recent studies to enhance TDSCs treatment of injured tendons. Finally, we identify the limitations of the current understanding of TDSCs biology, the main challenges of using their use, and potential therapeutic strategies to inform cell-based tendon repair.

Entities: Chemical

Keywords: Differentiation; Markers; Proliferation; Tendon injury; Tendon-derived stem cells

Mesh：

Year: 2021 PMID： 33651334 DOI： 10.1007/s12015-021-10143-9

Source DB: PubMed Journal: Stem Cell Rev Rep ISSN： 2629-3277 Impact factor: 5.739

115 in total

Review 1. Rescue plan for Achilles: Therapeutics steering the fate and functions of stem cells in tendon wound healing.

Authors: Magdalena Schneider; Peter Angele; Tero A H Järvinen; Denitsa Docheva
Journal: Adv Drug Deliv Rev Date: 2017-12-24 Impact factor: 15.470

2. Three-dimensional self-assembling nanofiber matrix rejuvenates aged/degenerative human tendon stem/progenitor cells.

Authors: Heyong Yin; Franziska Strunz; Zexing Yan; Jiaju Lu; Christoph Brochhausen; Stefanie Kiderlen; Hauke Clausen-Schaumann; Xiumei Wang; Manuela E Gomes; Volker Alt; Denitsa Docheva
Journal: Biomaterials Date: 2020-01-21 Impact factor: 12.479

3. The effect of tendon stem/progenitor cell (TSC) sheet on the early tendon healing in a rat Achilles tendon injury model.

Authors: Issei Komatsu; James H-C Wang; Kiyotaka Iwasaki; Tatsuya Shimizu; Teruo Okano
Journal: Acta Biomater Date: 2016-06-18 Impact factor: 8.947

4. Aspirin promotes tenogenic differentiation of tendon stem cells and facilitates tendinopathy healing through regulating the GDF7/Smad1/5 signaling pathway.

Authors: Yunjiao Wang; Gang He; Hong Tang; Youxing Shi; Min Zhu; Xia Kang; Xuting Bian; Jingtong Lyu; Mei Zhou; Mingyu Yang; Miduo Mu; Wan Chen; Binghua Zhou; Chengsong Yuan; Jiqiang Zhang; Kanglai Tang
Journal: J Cell Physiol Date: 2019-10-21 Impact factor: 6.384

Review 5. Tendon stem progenitor cells: Understanding the biology to inform therapeutic strategies for tendon repair.

Authors: Bhavita Walia; Alice H Huang
Journal: J Orthop Res Date: 2018-10-18 Impact factor: 3.494

6. Preferential tendon stem cell response to growth factor supplementation.

Authors: Carolyn Holladay; Sunny-Akogwu Abbah; Colm O'Dowd; Abhay Pandit; Dimitrios I Zeugolis
Journal: J Tissue Eng Regen Med Date: 2014-01-29 Impact factor: 3.963

Review 7. Biologics for tendon repair.

Authors: Denitsa Docheva; Sebastian A Müller; Martin Majewski; Christopher H Evans
Journal: Adv Drug Deliv Rev Date: 2014-11-21 Impact factor: 15.470

Review 8. Tendon Vasculature in Health and Disease.

Authors: Herbert Tempfer; Andreas Traweger
Journal: Front Physiol Date: 2015-11-18 Impact factor: 4.566

Review 9. Boosting tendon repair: interplay of cells, growth factors and scaffold-free and gel-based carriers.

Authors: Zexing Yan; Heyong Yin; Michael Nerlich; Christian G Pfeifer; Denitsa Docheva
Journal: J Exp Orthop Date: 2018-01-05

10. Aged Tendon Stem/Progenitor Cells Are Less Competent to Form 3D Tendon Organoids Due to Cell Autonomous and Matrix Production Deficits.

Authors: Zexing Yan; Heyong Yin; Christoph Brochhausen; Christian G Pfeifer; Volker Alt; Denitsa Docheva
Journal: Front Bioeng Biotechnol Date: 2020-05-05

3 in total